Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Naing Naing Mon"'
Autor:
Junichi Matsuo, Naing Naing Mon, Daisuke Douchi, Akihiro Yamamura, Madhura Kulkarni, Dede Liana Heng, Sabirah Chen, Napat Nuttonmanit, Ying Li, Henry Yang, May Yin Lee, Wai Leong Tam, Motomi Osato, Linda Shyue Huey Chuang, Yoshiaki Ito
Publikováno v:
Stem Cells. 40:112-122
Mammary gland homeostasis is maintained by adult tissue stem-progenitor cells residing within the luminal and basal epithelia. Dysregulation of mammary stem cells is a key mechanism for cancer development. However, stem cell characterization is chall
Autor:
Khine Myint, Kazuyoshi Kohu, Jinmiao Chen, Dede Liana Heng, Makoto Adachi, Sachiko Tsukita, Napat Nuttonmanit, Nur Astiana Mawan, Nicole Yee Shin Lee, Ying Li, Shamaine Wei Ting Ho, Junichi Matsuo, Khay Guan Yeoh, Sabirah Chen, Henry Yang, Atsushi Tamura, Wei Peng Yong, Naing Naing Mon, Hong Kai Lee, Jimmy Bok Yan So, Supriya Srivastava, Daisuke Douchi, Akihiro Yamamura, Patrick Tan, Linda Shyue Huey Chuang, Yoshiaki Ito, Ming Teh
Publikováno v:
Gut
ObjectiveTissue stem cells are central regulators of organ homoeostasis. We looked for a protein that is exclusively expressed and functionally involved in stem cell activity in rapidly proliferating isthmus stem cells in the stomach corpus.DesignWe
Publikováno v:
Oncology Letters. Feb2017, Vol. 13 Issue 2, p955-960. 6p.
Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair.
Autor:
Junichi Matsuo, Daisuke Douchi, Khine Myint, Naing Naing Mon, Akihiro Yamamura, Kazuyoshi Kohu, Dede Liana Heng, Sabirah Chen, Mawan, Nur Astiana, Napat Nuttonmanit, Ying Li, Srivastava, Supriya, Shamaine Wei Ting Ho, Yee Shin Lee, Nicole, Hong Kai Lee, Makoto Adachi, Atsushi Tamura, Jinmiao Chen, Yang, Henry, Ming Teh
Publikováno v:
Gut; Oct2021, Vol. 70 Issue 10, p1833-1846, 14p
Publikováno v:
Oncology Letters. 13:955-960
Interleukin-1β (IL-1b) is a pleiotropic cytokine that is important in tumor progression and invasion. Matrix metalloproteinase-9 (MMP-9), which is a secreted matrix-degrading enzyme, is one of the key regulators of tumor invasion and metastasis. The
Autor:
Christian Harteneck, Vedula Sri Ram Krishna, Jean Paul Thiery, Tuan Zea Tan, Benedict Yan, Qingsong Lin, Patrick Tan, Lee Yee Choong, Ssu-Yi Lu, Martin Johansson, Yoon Pin Lim, Naing Naing Mon, Himanshu Singh, Brendan Pang, Chwee Teck Lim, Wen Hsin Lee
Publikováno v:
Scientific Reports
Metastasis is a significant health issue. The standard mode of care is combination of chemotherapy and targeted therapeutics but the 5-year survival rate remains low. New/better drug targets that can improve outcomes of patients with metastatic disea
Autor:
Akihiro Yamamura, Dede L. Heng, Motomi Osato, Naing Naing Mon, Junichi Matsuo, Linda Sh Chuang, Yoshiaki Ito
Publikováno v:
Cancer Research. 78:5110-5110
In breast cancer, 83% of patients were diagnosed as hormone receptor positive, luminal-type, breast cancer (Anderson et al., 2014). Although primary luminal-type breast cancer can be controlled by endocrine therapy, more than 20% of patients have rec
Autor:
Naing Naing Mon, Michinari Hamaguchi, Reiji Kannagi, Pengyu Huang, A.R.M. Ruhul Amin, Md. Helal Uddin Biswas, Takeshi Senga, Hitoki Hasegawa, M. Aminur Rahman
Publikováno v:
Biochemical and Biophysical Research Communications. 348:1145-1149
To search for the signaling critical for the production of tissue inhibitor of metalloproteinase-2 (TIMP-2), we investigated the role of SHP-2 in TIMP-2 production with Concanavalin A (Con A)-treated cells. In wild-type fibroblasts, Con A-treatment d
Autor:
Pengyu Huang, Aye Aye Thant, Takeshi Senga, Naing Naing Mon, Yoko Tanimura, Michinari Hamaguchi, Hitoki Hasegawa
Publikováno v:
Cancer Research. 66:6778-6784
We have previously reported that tumor necrosis factor-α (TNF-α) stimulation of CCKS1, a cell line established from cholangiocarcinoma with i.p. dissemination, dramatically increased matrix metalloproteinase-9 (MMP-9) production and tumor invasion.
Autor:
Takeshi Senga, Naing Naing Mon, Myat Lin Oo, Pengyu Huang, Aye Aye Thant, Arm Ruhul Amin, Michinari Hamaguchi
Publikováno v:
Oncogene. 22:1411-1417
To evaluate the function of cysteine residues of the Src kinase, we constructed a series of Src mutants in which some of cysteines were replaced to alanines. With these mutants, we studied the effect of SH-alkylating agents, N-[p-(2-benzimidazolyl)ph