Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Naima Zahir"'
Autor:
Evi Schmid, Nguyen Thi Xuan, Naima Zahir, Antonella Russo, Wenting Yang, Dietmar Kuhl, Caterina Faggio, Ekaterina Shumilina, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 3, Pp 943-954 (2014)
Background/Aims: Dendritic cells (DCs), antigen-presenting cells linking innate and adaptive immunity, are required for initiation of specific T cell-driven immune responses. Phosphoinositide-3-kinase (PI3K) suppresses proinflammatory cytokine produc
Externí odkaz:
https://doaj.org/article/7e36daa979814668a0586d2e85ae96a2
Autor:
Jinyi Zhang1,2,3,4,5, Naima Zahir1,2,3,4,5, Qiuhong Jiang1,2,3,4,5, Helen Miliotis1,2,3,4,5, Stephanie Heyraud1,2,3,4,5, Xianwang Meng1,2,3,4,5, Baoxia Dong1,2,3,4,5, Gang Xie1,2,3,4,5, Frank Qiu1,2,3,4,5, Zhenyue Hao6, McCulloch, Christopher A.7, Keystone, Edward C.1, Peterson, Alan C.8, Siminovitch, Katherine A.1,2,3,4,5 ksimin@mshri.on.ca
Publikováno v:
Nature Genetics. Sep2011, Vol. 43 Issue 9, p902-907. 6p. 2 Black and White Photographs, 4 Graphs.
Autor:
Stephanie Heyraud, Helen MiliotisH. Miliotis, Xianwang Meng, Katherine A. Siminovitch, Alan C. Peterson, Baoxia Dong, Naima Zahir, Qiuhong Jiang, Gang Xie, Zhenyue Hao, Jinyi Zhang, Edward C. Keystone, Frank Qiu, Christopher A. McCulloch
Publikováno v:
Nature Genetics. 43:902-907
A variant of the PTPN22-encoded Lyp phosphatase (Lyp620W) confers risk for autoimmune disease, but the mechanisms underlying this association remain unclear. We show here that mice expressing the Lyp variant homolog Pep619W manifest thymic and spleni
Autor:
Stefan Kramer, Corinna Geiger, Reinhard Kandolf, Susanne Aberle, Naima Zahir, Adrian Lupescu, C-Thomas Bock, Philipp A. Lang, Sebastian Wesselborg, Michael Föller, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry. 23:211-220
Infection with parvovirus B19 (B19) may induce apoptosis resulting in anemia, acute fulminant liver failure, placental insufficiency and myocarditis. Apoptosis has been attributed to proapoptotic acti
Autor:
Roman Rösemann, Naima Zahir, Daniela Gunst, Ingo B. Autenrieth, Hermann Wagner, Klaus Ruckdeschel, Stefan Borgmann, Irena Soldanova, Michael Kracht, Stella E. Autenrieth
Publikováno v:
Cellular Microbiology. 9:425-437
Yersinia enterocolitica (Ye) targets mouse dendritic cells (DCs) and inhibits their ability to trigger T cell activation. Here we have investigated whether Ye might interfere with antigen presentation in DCs. Infection of DCs with the Ye wild-type st
Autor:
Malgorzata Sobiesiak, Tilo Biedermann, Ekaterina Shumilina, Susanne Kaesler, Adrian Lupescu, Florian Lang, Dietmar Kuhl, Martin Schaller, Florian Wölbing, Irina M. Zemtsova, Rebecca S. Lam, Nicole Matzner, Naima Zahir
Publikováno v:
ResearcherID
The PI3K pathway plays a pivotal role in the stimulation of mast cells. PI3K-dependent kinases include the serum- and glucocorticoid-inducible kinase 1 (SGK1). The present study explored the role of SGK1 in mast cell function. Mast cells were isolate
Autor:
Adrian, Lupescu, Corinna, Geiger, Naima, Zahir, Susanne, Aberle, Philipp A, Lang, Stefan, Kramer, Sebastian, Wesselborg, Reinhard, Kandolf, Michael, Foller, Florian, Lang, C-Thomas, Bock
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 23(1-3)
Infection with parvovirus B19 (B19) may induce apoptosis resulting in anemia, acute fulminant liver failure, placental insufficiency and myocarditis. Apoptosis has been attributed to proapoptotic activity of the non-structural viral protein NS1, whic
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 20(6)
The phosphoinositide 3 (PI3) kinase plays a pivotal role in the regulation of dendritic cells (DCs), antigen-presenting cells that are able to initiate primary immune responses and to establish immunological memory. PI3 kinase is an endogenous suppre
Autor:
Naima Zahir, Burghart Jilge, Julia-Stefanie Frick, Jörg Reimann, Erwin Bohn, Oliver Bechtold, Ingo B. Autenrieth
Publikováno v:
Inflammatory bowel diseases. 12(9)
Background: Specific pathogen-free (SPF), but not germfree (GF), interleukin (IL)-2-deficient (IL-2 -/- ) mice develop inflammatory bowel disease (IBD) at 10 to 15 weeks of age. Gnotobiotic IL-2 -/- mice monocolonized with E. coli mpk develop IBD at
Autor:
Manfred B. Lutz, Frauke Kahl, Ingo B. Autenrieth, Jörg Reimann, Carsten J. Kirschning, Martina Müller, Julia S. Frick, Erwin Bohn, Oliver Bechtold, Burghard Jilge, Naima Zahir
Publikováno v:
European journal of immunology. 36(6)
We investigated whether commensal bacteria modulate activation and maturation of bone marrow-derived DC and their ability to prime CD4(+) T cells. We used Escherichia coli mpk, which induces colitis in gnotobiotic IL-2-deficient (IL-2(-/-)) mice, and