Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Naim-Akhtar Khan"'
Dietary linoleic acid supplementation protects against obesity-induced microglial reactivity in mice
Autor:
Lucas Jantzen, Stéphanie Dumontoy, Bahrie Ramadan, Christophe Houdayer, Emmanuel Haffen, Aziz Hichami, Naim Akhtar Khan, Vincent Van Waes, Lidia Cabeza
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract We investigated whether linoleic acid (LA) supplementation could modulate emotional behavior and microglia-related neuroinflammation. For that, male mice of C57BL/6J genetic background fed either a high-fat diet (HFD) or a standard diet (STD
Externí odkaz:
https://doaj.org/article/54ac488b685b47a08c5189d00609cd23
Autor:
Amira Sayed Khan, Aziz Hichami, Babar Murtaza, Marie-Laure Louillat-Habermeyer, Christophe Ramseyer, Maryam Azadi, Semen Yesylevskyy, Floriane Mangin, Frederic Lirussi, Julia Leemput, Jean-Francois Merlin, Antonin Schmitt, Muhtadi Suliman, Jérôme Bayardon, Saeed Semnanian, Sylvain Jugé, Naim Akhtar Khan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 633-663 (2023)
Background & Aims: The spontaneous preference for dietary lipids is principally regulated by 2 lingual fat taste receptors, CD36 and GPR120. Obese animals and most of human subjects exhibit low orosensory perception of dietary fat because of malfunct
Externí odkaz:
https://doaj.org/article/faac987bf7904e528f779ff44b123109
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Obesity and related metabolic disorders are associated with genetic and epigenetic alterations. In this study, we have examined the association between polymorphisms and hypermethylation of the CD36 gene promoter with obesity in S
Externí odkaz:
https://doaj.org/article/74d52f76330a4dd580d60b36b4f644ec
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/abb89a56588d46a6a68e49cbaaa926f9
Autor:
Abdelhafid Nani, Meriem Belarbi, Babar Murtaza, Chahid Benammar, Taha Merghoub, Mickaël Rialland, Naim Akhtar Khan, Aziz Hichami
Publikováno v:
Journal of Functional Foods, Vol 54, Iss , Pp 422-432 (2019)
Osteosarcoma is the most common bone tumor with a high prevalence among children and adolescents. Polyphenols are widely investigated for their chemopreventive and chemotherapeutic proprieties. In the present study, we explored the pro-apoptotic effe
Externí odkaz:
https://doaj.org/article/8cac7800a5f84aa89a6e085c1d9c7ba9
Autor:
Hasnae Benkirane, Jaafar Heikel, Fatima Zahra Laamiri, Amina Bouziani, Houria Lahmam, Ayoub Al-Jawaldeh, Noureddine El Haloui, Khalid Ennibi, Naim Akhtar-Khan, El Mostafa El Fahime, Majdouline Obtel, Amina Barkat, Hassan Aguenaou
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
BackgroundThe epidemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19), presents a significant and urgent threat to global health. This alarming viral infection, declared as pandemic by the
Externí odkaz:
https://doaj.org/article/cb418de31a9c4042ac98036e1ece7954
Autor:
Lorène J. Lebrun, Kaatje Lenaerts, Dorien Kiers, Jean-Paul Pais de Barros, Naig Le Guern, Jiri Plesnik, Charles Thomas, Thibaut Bourgeois, Cornelis H.C. Dejong, Matthijs Kox, Inca H.R. Hundscheid, Naim Akhtar Khan, Stéphane Mandard, Valérie Deckert, Peter Pickkers, Daniel J. Drucker, Laurent Lagrost, Jacques Grober
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1160-1168 (2017)
Summary: Glucagon-like peptide 1 (GLP-1) is a hormone released from enteroendocrine L cells. Although first described as a glucoregulatory incretin hormone, GLP-1 also suppresses inflammation and promotes mucosal integrity. Here, we demonstrate that
Externí odkaz:
https://doaj.org/article/54c442ddf2554e8d93b3af382d5f41cd
Autor:
Fatima Zahra Ghanemi, Meriem Belarbi, Aurélie Fluckiger, Abdelhafid Nani, Adélie Dumont, Charlotte De Rosny, Ikram Aboura, Amira Sayed Khan, Babar Murtaza, Chahid Benammar, Boucif Farid Lahfa, Danish Patoli, Dominique Delmas, Cédric Rébé, Lionel Apétoh, Naim Akhtar Khan, François Ghringhelli, Mickael Rialland, Aziz Hichami
Publikováno v:
Journal of Functional Foods, Vol 33, Iss , Pp 112-121 (2017)
Chemoprevention of Colorectal cancer (CRC) is the major concern for improving public health. We investigated the protective effects of carob, Ceratonia siliqua L., leaf polyphenols (CLP) against CRC. Phenolic content analysis showed that CLP is enric
Externí odkaz:
https://doaj.org/article/ea2fdcc0f1df4d1b8f1c1dcb248d0ded
Publikováno v:
Molecules, Vol 26, Iss 4, p 985 (2021)
Nutrition transition can be defined as shifts in food habits, and it is characterized by high-fat (chiefly saturated animal fat), hypercaloric and salty food consumption at the expense of dietary fibers, minerals and vitamins. Western dietary pattern
Externí odkaz:
https://doaj.org/article/08572ce4eedf405895c72781d435d61c
Autor:
Déborah Ancel, Arnaud Bernard, Selvakumar Subramaniam, Akira Hirasawa, Gozoh Tsujimoto, Toshihiro Hashimoto, Patricia Passilly-Degrace, Naim-Akhtar Khan, Philippe Besnard
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 369-378 (2015)
Implication of the long-chain fatty acid (LCFA) receptor GPR120, also termed free fatty acid receptor 4, in the taste-guided preference for lipids is a matter of debate. To further unravel the role of GPR120 in the “taste of fat”, the present stu
Externí odkaz:
https://doaj.org/article/f9e5afadd8594f378d8fa1602c04c395