Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Naim U. Rashid"'
Autor:
Luke A. Torre-Healy, Ryan R. Kawalerski, Ki Oh, Lucie Chrastecka, Xianlu L. Peng, Andrew J. Aguirre, Naim U. Rashid, Jen Jen Yeh, Richard A. Moffitt
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
pdacR is an open-source R package and web-based platform that enables community exploration of pancreatic ductal adenocarcinoma (PDAC) gene expression datasets. pdacR is used to interrogate the specificities of popular PDAC molecular subtypes.
Externí odkaz:
https://doaj.org/article/f01dcb81e2df4174b75f2a337239323f
Autor:
Steven P. Angus, Timothy J. Stuhlmiller, Gaurav Mehta, Samantha M. Bevill, Daniel R. Goulet, J. Felix Olivares-Quintero, Michael P. East, Maki Tanioka, Jon S. Zawistowski, Darshan Singh, Noah Sciaky, Xin Chen, Xiaping He, Naim U. Rashid, Lynn Chollet-Hinton, Cheng Fan, Matthew G. Soloway, Patricia A. Spears, Stuart Jefferys, Joel S. Parker, Kristalyn K. Gallagher, Andres Forero-Torres, Ian E. Krop, Alastair M. Thompson, Rashmi Murthy, Michael L. Gatza, Charles M. Perou, H. Shelton Earp, Lisa A. Carey, Gary L. Johnson
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Inhibition of the HER2/ERBB2 receptor is a keystone to treating HER2-positive malignancies, particularly breast cancer, but a significant fraction of HER2-positive (HER2+) breast cancers recur or fail to respond. Anti-HER2 monoclonal antibod
Externí odkaz:
https://doaj.org/article/c11b8d70dbc348e48996b9c35fbb436b
Autor:
Katerina D. Fagan-Solis, Dennis A. Simpson, Rashmi J. Kumar, Luciano G. Martelotto, Lisle E. Mose, Naim U. Rashid, Alice Y. Ho, Simon N. Powell, Y. Hannah Wen, Joel S. Parker, Jorge S. Reis-Filho, John H.J. Petrini, Gaorav P. Gupta
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1385-1399.e7 (2020)
Summary: The Mre11-Rad50-Nbs1 complex is a DNA double-strand break sensor that mediates a tumor-suppressive DNA damage response (DDR) in cells undergoing oncogenic stress, yet the mechanisms underlying this effect are poorly understood. Using a genet
Externí odkaz:
https://doaj.org/article/c748e1c4c3444689abb982bb24303a91
Publikováno v:
Biostatistics.
Summary Differential transcript usage (DTU) occurs when the relative expression of multiple transcripts arising from the same gene changes between different conditions. Existing approaches to detect DTU often rely on computational procedures that can
Autor:
Yuliya Pylayeva-Gupta, Dario A.A. Vignali, Benjamin G. Vincent, Autumn J. McRee, Jen Jen Yeh, Naim U. Rashid, David G. DeNardo, William G. Hawkins, Ryan C. Fields, Gaorav P. Gupta, Emily C. Goldman, Kevin Greene, Cameron Harris, Nancy P. Kren, Samuel J. Lee, Daniel Michaud, Bhalchandra Mirlekar
Supplementary Tables 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350bb8dc2469a732d9adbe9922490c43
https://doi.org/10.1158/2326-6066.22543597
https://doi.org/10.1158/2326-6066.22543597
Autor:
Yuliya Pylayeva-Gupta, Dario A.A. Vignali, Benjamin G. Vincent, Autumn J. McRee, Jen Jen Yeh, Naim U. Rashid, David G. DeNardo, William G. Hawkins, Ryan C. Fields, Gaorav P. Gupta, Emily C. Goldman, Kevin Greene, Cameron Harris, Nancy P. Kren, Samuel J. Lee, Daniel Michaud, Bhalchandra Mirlekar
Supplementary Figures 1-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9264c87b1e463083a799ae5ef6cc4d
https://doi.org/10.1158/2326-6066.22543600
https://doi.org/10.1158/2326-6066.22543600
Autor:
Yuliya Pylayeva-Gupta, Dario A.A. Vignali, Benjamin G. Vincent, Autumn J. McRee, Jen Jen Yeh, Naim U. Rashid, David G. DeNardo, William G. Hawkins, Ryan C. Fields, Gaorav P. Gupta, Emily C. Goldman, Kevin Greene, Cameron Harris, Nancy P. Kren, Samuel J. Lee, Daniel Michaud, Bhalchandra Mirlekar
Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignancy characterized by a paucity of tumor-proximal CD8+ T cells and resistance to immunotherapeutic interventions. Cancer-associated mechanisms that elicit CD8+ T-cell exclusion and resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90da6048b085cbe52b7e8284e6243974
https://doi.org/10.1158/2326-6066.c.6550327
https://doi.org/10.1158/2326-6066.c.6550327
Autor:
Gary L. Johnson, Jon S. Zawistowski, Steven P. Angus, Charlene M. Santos, Nathaniel J. Moorman, Andrew Hale, Timothy J. Stuhlmiller, Naim U. Rashid, Adriana S. Beltran, Darshan Singh, Brian T. Golitz, Noah Sciaky, Jose F. Olivares-Quintero, Samantha M. Bevill
File includes drug synergy scores for 1 cell line screened against OTX015
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a25e1d1b980bfd39e3876778cdebb5
https://doi.org/10.1158/1541-7786.22513420.v1
https://doi.org/10.1158/1541-7786.22513420.v1
Autor:
Gary L. Johnson, Jon S. Zawistowski, Steven P. Angus, Charlene M. Santos, Nathaniel J. Moorman, Andrew Hale, Timothy J. Stuhlmiller, Naim U. Rashid, Adriana S. Beltran, Darshan Singh, Brian T. Golitz, Noah Sciaky, Jose F. Olivares-Quintero, Samantha M. Bevill
File contains information on small molecules included in screening library
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e500f09a798f7186892bf9a32f9e558f
https://doi.org/10.1158/1541-7786.22513426.v1
https://doi.org/10.1158/1541-7786.22513426.v1
Autor:
Gary L. Johnson, Jon S. Zawistowski, Steven P. Angus, Charlene M. Santos, Nathaniel J. Moorman, Andrew Hale, Timothy J. Stuhlmiller, Naim U. Rashid, Adriana S. Beltran, Darshan Singh, Brian T. Golitz, Noah Sciaky, Jose F. Olivares-Quintero, Samantha M. Bevill
File includes AlphaScreening values for activity of the screening library against the BET or p300 bromodomains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca58033c88ff333e059b8d6933e936f7
https://doi.org/10.1158/1541-7786.22513414.v1
https://doi.org/10.1158/1541-7786.22513414.v1