Zobrazeno 1 - 2
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pro vyhledávání: '"Naiju Zhu"'
Autor:
Cheryl Klein-Stevens, Naiju Zhu, Leyte L. Winfield, Stacey A. Lomenzo, Theresa Kopajtic, Mark L. Trudell, Jonathan L. Katz, Lifen Xu, Sari Izenwasser
Publikováno v:
Journal of Medicinal Chemistry. 45:1203-1210
A series of eight 2-substituted 3-tolyltropane derivatives were synthesized, and the in vitro and in vivo biological activities as dopamine uptake inhibitors were determined. From the in vitro structure-activity data, it is apparent that a tolyl grou
Publikováno v:
Organic letters. 1(9)
[formula: see text] The syntheses of both exo and endo stereoisomers of 7-methyl-7-azabicyclo[2.2.1]heptan-2-ol were achieved in straightforward fashion. Alternatively, the intramolecular cyclization of syn-4-N-methylaminocyclohexane 1,2-epoxide was