Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Naijia Huang"'
Autor:
David T. White, Naijia Huang, Jeffrey S. Tan, Kenneth J. Ruterbories, Jason Liu, Derek Brocksmith, Lee J. Burns, Alain Stricker-Krongrad, Nathan Yumibe, Nita J. Patel, Guy Bouchard
Publikováno v:
International Journal of Pharmacokinetics. 2:81-91
Aim: Oral and intravenous pharmacokinetic (PK) studies were conducted in four different minipig strains: Sinclair, Yucatan, Hanford and Göttingen after administration of metformin or R,S-verapamil (R,S-VER). Results: The results indicated that the P
Autor:
Robert D Dally, Yu-Hua Hui, Haitao Hu, Palaniappan Kulanthaivel, Naijia Huang, Ping Yi, William J. Ehlhardt
1. Nuclear magnetic resonance (NMR), a non-selective and inherently quantitative method, has not been widely used as a quantitative tool for characterizing the disposition of lead molecules prior to clinical development. As a test case, we have chose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e380f43d749f9a44fedf7d479033f9d
Autor:
James S. Bean, Raymond F. Kauffman, Jaipal Singh, Ashraf Saeed, Robert J. Barr, Chahrzad Montrose-Rafizadeh, William R. Bensch, Deepa Rungta, John J. Osborne, Daniel Ray Mayhugh, Naijia Huang, Dale E. Maise, Nathan Yumibe, Xiaodong Wang, Richard Craig Thompson, Samuel J. Dominianni, Debra Luffer-Atlas, Nathan Bryan Mantlo, Richard W. Zink, Yanping Xu
Publikováno v:
Journal of medicinal chemistry. 46(24)
A new series of hPPARalpha agonists containing a 2,4-dihydro-3H-1,2,4-triazol-3-one (triazolone) core is described leading to the discovery of 5 (LY518674), a highly potent and selective PPARalpha agonist.
Autor:
Naijia Huang, Catherine Sekerke, Y. Y. Shum, Gary A. Walter, Lloyd R. Whitfield, Ann Black, Tsun Chang
Publikováno v:
Therapeutic drug monitoring. 20(1)
An HMG-CoA reductase inhibition assay was developed and validated for quantitation of atorvastatin in human, dog, rat, and mouse plasma. Atorvastatin was isolated from plasma by protein precipitation. Rat-liver microsomes were used to provide the red