Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Naihui, Chu"'
Deciphering the possible role of MmpL7 efflux pump in SQ109 resistance in Mycobacterium tuberculosis
Autor:
Wei Jing, Fuzhen Zhang, Yuanyuan Shang, Wenhui Shi, Cong Yao, Xuxia Zhang, Naihui Chu, Jie Lu, Jinfeng Yuan
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-8 (2024)
Abstract Background SQ109 is a promising candidate drug for the treatment of patients with drug-resistant tuberculosis (DR-TB). The purpose of this study was to investigate the activity of SQ109 against clinical isolates of Mycobacterium tuberculosis
Externí odkaz:
https://doaj.org/article/3e985dad22e4420a86f80f32171e487f
Autor:
Xiaojing Yan, Guoli Yang, Yunfei Wang, Yuqing Wang, Jie Cheng, Peisong Xu, Xiaoli Qiu, Lei Su, Lina Liu, Ruixue Geng, Yingxia You, Hui Liu, Naihui Chu, Li Ma, Wenjuan Nie
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Purpose In this prospective study, the diagnosis accuracy of nanopore sequencing-based Mycobacterium tuberculosis (MTB) detection was determined through examining bronchoalveolar lavage fluid (BALF) samples from pulmonary tuberculosis (PTB)
Externí odkaz:
https://doaj.org/article/35985f4fa51f46dba434288d2bdc96d1
Publikováno v:
BMC Medical Imaging, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Objective To evaluate the consistency between doctors and artificial intelligence (AI) software in analysing and diagnosing pulmonary nodules, and assess whether the characteristics of pulmonary nodules derived from the two methods are consi
Externí odkaz:
https://doaj.org/article/83bd63557e674415a5ed951b504fbf25
Autor:
Yuanyuan Shang, Suting Chen, Wenhui Shi, Wenjuan Nie, Wei Jing, Fengmin Huo, Yi Xue, Lingling Dong, Guanglu Jiang, Hairong Huang, Naihui Chu
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 33, Iss , Pp 294-300 (2023)
ABSTRACT: Objectives: Bedaquiline (BDQ) is a potent drug for treating drug-resistant tuberculosis (TB). Here, we analysed the resistance profiles of BDQ in CFZ-resistant clinical isolates and investigated the clinical risk factors of BDQ and CFZ cros
Externí odkaz:
https://doaj.org/article/fff216554ba346d1a1e4b90236c4c109
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background To determine the diagnostic accuracy of a nanopore sequencing assay of PCR products from a M. tuberculosis complex-specific region for testing of bronchoalveolar lavage fluid (BALF) samples or sputum samples from suspected pulmona
Externí odkaz:
https://doaj.org/article/18b864c4cdf64aaa9df493bbd8d1e0fc
Autor:
Yaoyao Kong, Zhi Geng, Guanglu Jiang, Junnan Jia, Fen Wang, Xiaoyi Jiang, Yuzhen Gu, Zhenyan Qi, Naihui Chu, Hairong Huang, Xia Yu
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21216- (2023)
Objective: The resistance of Mycobacterium tuberculosis (Mtb) to currently available fluoroquinolones (FQs), namely ofloxacin (OFX), levofloxacin (LFX), and moxifloxacin (MFX), renders the treatment of TB infections less successful. In this study, we
Externí odkaz:
https://doaj.org/article/6daf832b8c874df2b1a837348f9eb55a
Autor:
Lu Xia, Miao Xu, Feng Li, Tao Li, Heng Yang, Weihua Wang, Qi Wu, Youlun Li, Xiaohong Chen, Qinfang Ou, Naihui Chu, Hongqiu Pan, Qunyi Deng, Xiaodong Mei, Douglas B Lowrie, Xuhui Liu, Guozhi Wang, Shuihua Lu
Publikováno v:
International Journal of Infectious Diseases, Vol 126, Iss , Pp 98-103 (2023)
Objectives: To verify the diagnostic utility of recombinant fusion protein ESAT6-CPF10 (EC), a novel skin test reagent to detect Mycobacterium tuberculosis infection. Methods: A multi-centered, double-blind, randomized controlled trial was conducted
Externí odkaz:
https://doaj.org/article/0eb3217a95ed425787af5c403e134113
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
ObjectiveThis study aimed to investigate sudapyridine (WX-081) antibacterial activity against Mycobacterium abscessus in vitro and its effect on in vivo bacterial growth and host survival using a zebrafish model of M. abscessus infection.MethodsWX-08
Externí odkaz:
https://doaj.org/article/6f388f9575384b0ea39459bbbd11b529
Antibacterial activity of the novel oxazolidinone contezolid (MRX-I) against Mycobacterium abscessus
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
ObjectiveTo evaluate contezolid (MRX-I) antibacterial activity against Mycobacterium abscessus in vitro and in vivo and to assess whether MRX-I treatment can prolong survival of infected zebrafish.MethodsMRX-I inhibitory activity against M. abscessus
Externí odkaz:
https://doaj.org/article/1803f8a66f374b0bba68dac2bdd2eaa2
Publikováno v:
Frontiers in Public Health, Vol 10 (2023)
PurposeThe present study aimed to explore the risk factors for tuberculous meningitis (TBM) among patients with tuberculosis (TB).MethodsThis retrospective study was conducted on patients with TB who were hospitalized in Beijing Chest Hospital betwee
Externí odkaz:
https://doaj.org/article/fd8be173843343b8a139341aeeaf6724