Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Naihong Yan"'
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1138 (2024)
Diabetic retinopathy (DR) is one of the most severe complications of diabetes mellitus and potentially leads to significant visual impairment and blindness. The complex mechanisms involved in the pathological changes in DR make it challenging to achi
Externí odkaz:
https://doaj.org/article/40d4c8028bc1441fad7083a92023530e
Publikováno v:
Bioactive Materials, Vol 14, Iss , Pp 134-144 (2022)
Choroidal neovascularization (CNV) is a common pathological feature of various eye diseases and an important cause of visual impairment in middle-aged and elderly patients. In previous studies, tetrahedral framework nucleic acids (tFNAs) showed good
Externí odkaz:
https://doaj.org/article/a368671f7e6a4df780442ef28b4c3d4c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Retinitis pigmentosa (RP) is an important cause of irreversible blindness worldwide and lacks effective treatment strategies. Although mutations are the primary cause of RP, research over the past decades has shown that neuroinflammation is an import
Externí odkaz:
https://doaj.org/article/5175dcc4be2b492e9fa32e2aeffa1116
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Although gene mutations and aberrant chromosomes are associated with the pathogenesis and prognosis of uveal melanoma (UM), potential therapeutic targets still need to be explored. We aim to determine the predictive value and potential therapeutic ta
Externí odkaz:
https://doaj.org/article/4a7da9735bd74e60a0bd6ffd47d7d3a9
Autor:
Xiang Ren, Yunxia Gao, Yu Lin, Xiangyu Fu, Lirong Xiao, Xiaoyue Wang, Zhibing Zeng, Li Bao, Naihong Yan, Ming Zhang, Li Tang
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundMicrophthalmos (MCO) is a rare developmental defect characterized by small malformed eyes. Our study aimed to describe the clinical characteristics of posterior microphthalmos syndrome caused by a novel variant in MFRP gene in a Chinese pat
Externí odkaz:
https://doaj.org/article/aef00bfed1864e4b8c216854e33d39c0
Autor:
Yunxia Gao, Xiang Ren, Xiangyu Fu, Yu Lin, Lirong Xiao, Xiaoyue Wang, Naihong Yan, Ming Zhang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Purpose: Congenital cataract (CC) is a common disease resulting in leukocoria and the leading cause of blindness in children worldwide. Approximately 50% of congenital cataract is inherited. Our aim is to identify mutations in a Chinese family with c
Externí odkaz:
https://doaj.org/article/f97911af1d314e67974084921b80ef9e
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Purpose: Choroidal neovascularization (CNV) is the main pathogenic process and a leading cause of severe vision loss in neovascular age-related macular degeneration (AMD). We investigated the antiangiogenic efficacy of dihydroartemisinin (DHA) in an
Externí odkaz:
https://doaj.org/article/fc7eceb39fa54ae18f6aef5269c62c03
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Congenital nystagmus (CN) and congenital cataracts are distinct eye diseases and are usually isolated. Cases with CN and congenital cataracts caused by different genes in one family have been rarely reported. Case presentation A 2
Externí odkaz:
https://doaj.org/article/88990501a0ca49a5856c806873fb848d
Autor:
Lin Cheng, Lucy J Wong, Naihong Yan, Richard C Han, Honghua Yu, Chenying Guo, Khulan Batsuuri, Aniket Zinzuwadia, Ryan Guan, Kin-Sang Cho, Dong Feng Chen
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191853 (2018)
Epigenetic predisposition is thought to critically contribute to adult-onset disorders, such as retinal neurodegeneration. The histone methyltransferase, enhancer of zeste homolog 2 (Ezh2), is transiently expressed in the perinatal retina, particular
Externí odkaz:
https://doaj.org/article/059db07025ac45358eef4b0f6f177cf2
Autor:
Yun Wang, Liheng Guo, Su-Ping Cai, Meizhi Dai, Qiaona Yang, Wenhan Yu, Naihong Yan, Xiaomin Zhou, Jin Fu, Xinwu Guo, Pengfei Han, Jun Wang, Xuyang Liu
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e33673 (2012)
Retinitis pigmentosa (RP) is a heterogeneous group of progressive retinal degenerations characterized by pigmentation and atrophy in the mid-periphery of the retina. Twenty two subjects from a four-generation Chinese family with RP and thin cornea, c
Externí odkaz:
https://doaj.org/article/4ea70354204647438340d3c17d8cd051