Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Naihong, Chen"'
Autor:
Qian Yan, Shasha Liu, Yang Sun, Chen Chen, Yantao Yang, Songwei Yang, Meiyu Lin, Junpeng Long, Yuting Lin, Jinping Liang, Qidi Ai, Naihong Chen
Publikováno v:
Journal of Advanced Research, Vol 63, Iss , Pp 171-186 (2024)
Background: Pulmonary hypertension (PH) represents a progressive condition characterized by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and increased mortality rates. Substantial evidence has elucidated the piv
Externí odkaz:
https://doaj.org/article/c81828d1731e4d10ab61a4571ae62f5e
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 2057-2076 (2024)
Parkinson's disease (PD) is a neurodegeneration disease with α-synuclein accumulated in the substantia nigra pars compacta (SNpc) and most of the dopaminergic neurons are lost in SNpc while patients are diagnosed with PD. Exploring the pathology at
Externí odkaz:
https://doaj.org/article/1dc15eb260194a128499573398bd7bf5
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Depression is highly prevalent globally, however, currently available medications face challenges such as low response rates and short duration of efficacy. Additionally, depression mostly accompany other psychiatric disorders, further progr
Externí odkaz:
https://doaj.org/article/d437068d472a4b5490b51d11b29ce172
Autor:
Huiqin Wang, Yantao Yang, Songwei Yang, Siyu Ren, Juling Feng, Yangbo Liu, Haodong Chen, Naihong Chen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/e6672335357148cfbdd2635ab0d9261b
Autor:
Qian Yan, Shasha Liu, Yang Sun, Chen Chen, Songwei Yang, Meiyu Lin, Junpeng Long, Jiao Yao, Yuting Lin, Fan Yi, Lei Meng, Yong Tan, Qidi Ai, Naihong Chen, Yantao Yang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-35 (2023)
Abstract Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis (AS), and myocardial infarction (MI). Oxidative stress (OS)
Externí odkaz:
https://doaj.org/article/4f01e659c6484f139ac98513cba0c667
Publikováno v:
Brain Research Bulletin, Vol 209, Iss , Pp 110921- (2024)
Tunneling nanotubes (TNTs) have emerged as pivotal structures for intercellular communication, enabling the transfer of cellular components across distant cells. Their involvement in neurological disorders has attracted considerable scientific intere
Externí odkaz:
https://doaj.org/article/9affa8a375bb46bf9ace33b929f6e958
Autor:
Junpeng Long, Yang Sun, Shasha Liu, Songwei Yang, Chen Chen, Zhao Zhang, Shifeng Chu, Yantao Yang, Gang Pei, Meiyu Lin, Qian Yan, Jiao Yao, Yuting Lin, Fan Yi, Lei Meng, Yong Tan, Qidi Ai, Naihong Chen
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Stroke has caused tremendous social stress worldwide, yet despite decades of research and development of new stroke drugs, most have failed and rt-PA (Recombinant tissue plasminogen activator) is still the accepted treatment for ischemic str
Externí odkaz:
https://doaj.org/article/3ddaa99e66d1435ebfb3ab5ca18477d6
Autor:
Haodong Chen, Yangbo Liu, Juling Feng, Hongyun Wang, Yantao Yang, Qidi Ai, Zhao Zhang, Shifeng Chu, Naihong Chen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Anti-oxidant stress is a potential strategy for the treatment of ischemic stroke. Here, we found a novel free radical scavenger termed as CZK, which is derived from alkaloids contained in Clausena lansium. In this study, we first compared cy
Externí odkaz:
https://doaj.org/article/84245c9ffd5540c4a19dd0daa7a73429
Autor:
Yang Sun, Shasha Liu, Chen Chen, Songwei Yang, Gang Pei, Meiyu Lin, Ting Wang, Junpeng Long, Qian Yan, Jiao Yao, Yuting Lin, Fan Yi, Lei Meng, Yong Tan, Qidi Ai, Naihong Chen, Yantao Yang
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Pulmonary hypertension (PH) was a cardiovascular disease with high morbidity and mortality. PH was a chronic disease with complicated pathogenesis and uncontrollable factors. PH was divided into five groups according to its pathogenesis and
Externí odkaz:
https://doaj.org/article/5ed971af45b24002b9b1431b6e1c37d5
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 330 (2024)
Background: Glucuronidation is an essential metabolic pathway for a variety of drugs. IMM-H004 is a novel neuroprotective agent against ischemic stroke, and its glucuronide metabolite IMM-H004G exhibits similar pharmacological activity. Despite posse
Externí odkaz:
https://doaj.org/article/c446e6a70ac44b0ba49d19add20a8186