Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Naig, Gueguen"'
Autor:
Alison Robert, David Crottès, Jérôme Bourgeais, Naig Gueguen, Arnaud Chevrollier, Jean-François Dumas, Stéphane Servais, Isabelle Domingo, Stéphanie Chadet, Julien Sobilo, Olivier Hérault, Thierry Lecomte, Christophe Vandier, William Raoul, Maxime Guéguinou
Publikováno v:
PLoS Biology, Vol 22, Iss 10, p e3002854 (2024)
The mitochondrial Ca2+ uniporter (MCU) plays crucial role in intramitochondrial Ca2+ uptake, allowing Ca2+-dependent activation of oxidative metabolism. In recent decades, the role of MCU pore-forming proteins has been highlighted in cancer. However,
Externí odkaz:
https://doaj.org/article/d921cf1a11eb48efbb81622c970372c0
Autor:
Marta Zawadzka, Magdalena Krygier, Małgorzata Pawłowicz, Matheus Vernet Machado Bressan Wilke, Karolina Rutkowska, Naig Gueguen, Valerie Desquiret‐Dumas, Eric W. Klee, Lisa A. Schimmenti, Jarosław Sławek, Vincent Procaccio, Rafał Płoski, Maria Mazurkiewicz‐Bełdzińska
Publikováno v:
Clinical geneticsREFERENCES. 102(5)
Leigh syndrome (LS) is a progressive neurodegenerative disease, characterized by extensive clinical, biochemical, and genetic heterogeneity. Recently, biallelic variants in DNAJC30 gene, encoding a protein crucial for the repair of mitochondrial comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c52a86782d6a00a7bcd5f77cd2d340e
https://pubmed.ncbi.nlm.nih.gov/35861300
https://pubmed.ncbi.nlm.nih.gov/35861300
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(10)
Understanding temperature production and regulation in endotherm organisms becomes a crucial challenge facing the increased frequency and intensity of heat strokes related to global warming. Mitochondria, located at the crossroad of metabolism, respi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3dbf73dec82f4fa8e02426bb0f044a
https://pubmed.ncbi.nlm.nih.gov/36125552
https://pubmed.ncbi.nlm.nih.gov/36125552
Autor:
Mythily Ganapathi, Gaelle Friocourt, Naig Gueguen, Marisa W. Friederich, Gerald Le Gac, Volkan Okur, Nadège Loaëc, Thomas Ludwig, Chandran Ka, Kurenai Tanji, Pascale Marcorelles, Evangelos Theodorou, Angela Lignelli‐Dipple, Cécile Voisset, Melissa A. Walker, Lauren C. Briere, Amélie Bourhis, Marc Blondel, Charles LeDuc, Jacob Hagen, Cathleen Cooper, Colleen Muraresku, Claude Ferec, Armelle Garenne, Servane Lelez‐Soquet, Cassandra A. Rogers, Yufeng Shen, Dana K. Strode, Peyman Bizargity, Alejandro Iglesias, Amy Goldstein, Frances A. High, Undiagnosed Diseases Network, David A. Sweetser, Rebecca Ganetzky, Johan L. K. Van Hove, Vincent Procaccio, Cedric Le Marechal, Wendy K. Chung
Publikováno v:
Journal of inherited metabolic disease. 45(5)
Mitochondrial complex V plays an important role in oxidative phosphorylation by catalyzing the generation of ATP. Most complex V subunits are nuclear encoded and not yet associated with recognized Mendelian disorders. Using exome sequencing, we ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49cf2c2f3e1aad721af9beecf96b54e
https://pubmed.ncbi.nlm.nih.gov/35621276
https://pubmed.ncbi.nlm.nih.gov/35621276
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance
Autor:
Jade Aurrière, David Goudenege, Simone A. Baechler, Shar-Yin N. Huang, Naig Gueguen, Valerie Desquiret-Dumas, Floris Chabrun, Rodolphe Perrot, Arnaud Chevrollier, Majida Charif, Olivier R Baris, Yves Pommier, Guy Lenaers, Salim Khiati
Publikováno v:
Mitochondrion
Cancer/Testis Antigens (CTAs) represent a group of proteins whose expression under physiological conditions is restricted to testis but activated in many human cancers. Also, it was observed that co-expression of multiple CTAs worsens the patient pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4445dd0759229db7bb393ef2f5aad4df
https://europepmc.org/articles/PMC9057655/
https://europepmc.org/articles/PMC9057655/
Autor:
Michael Zech, Robert Kopajtich, Katja Steinbrücker, Céline Bris, Naig Gueguen, René G. Feichtinger, Melanie T. Achleitner, Neslihan Duzkale, Maximilien Périvier, Johannes Koch, Harald Engelhardt, Peter Freisinger, Matias Wagner, Theresa Brunet, Riccardo Berutti, Dmitrii Smirnov, Tharsini Navaratnarajah, Richard J.T. Rodenburg, Lynn S Pais, Christina Austin‐Tse, Melanie O'Leary, Sylvia Boesch, Robert Jech, Somayeh Bakhtiari, Sheng Chih Jin, Friederike Wilbert, Michael C Kruer, Saskia B. Wortmann, Matthias Eckenweiler, Johannes A. Mayr, Felix Distelmaier, Robert Steinfeld, Juliane Winkelmann, Holger Prokisch
Publikováno v:
Annals of Neurology, 91, 225-237
Ann Neurol
Annals of Neurology, 91, 2, pp. 225-237
Ann Neurol
Annals of Neurology, 91, 2, pp. 225-237
Contains fulltext : 248231.pdf (Publisher’s version ) (Open Access) OBJECTIVE: ATP synthase (ATPase) is responsible for the majority of ATP production. Nevertheless, disease phenotypes associated with mutations in ATPase subunits are extremely rare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf58a23e912f8d39b851e9a8f62fa265
https://doi.org/10.1002/ana.26293
https://doi.org/10.1002/ana.26293
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2276
Until recently restricted to hereditary mitochondrial diseases, mitochondrial dysfunction is now recognized as a key player and strategic factor in the pathophysiological of many human diseases, ranging from the metabolism, vascular, cardiac, and neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9270f742f7b398f38fd9a06b93528096
https://pubmed.ncbi.nlm.nih.gov/34060029
https://pubmed.ncbi.nlm.nih.gov/34060029
Autor:
Delphine Mirebeau-Prunier, Soazig Le Pennec, Caroline Jacques, Jean-Fred Fontaine, Naig Gueguen, Nathalie Boutet-Bouzamondo, Audrey Donnart, Yves Malthièry, Frédérique Savagner
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58683 (2013)
Metabolic modifications of tumor cells are hallmarks of cancer. They exhibit an altered metabolism that allows them to sustain higher proliferation rates in hostile environment outside the cell. In thyroid tumors, the expression of the estrogen-relat
Externí odkaz:
https://doaj.org/article/53a2b26cfc1a405c842e10c235e3de98
Autor:
Celine, Bris, Tiphaine, Rouaud, Valerie, Desquiret-Dumas, Naig, Gueguen, David, Goudenege, Magalie, Barth, Dominique, Bonneau, Patrizia, Amati-Bonneau, Guy, Lenaers, Pascal, Reynier, Anne-Sophie, Lebre, Vincent, Procaccio
Publikováno v:
Neurology: Genetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5978eceba35e18c59d9aa2d38645da0
https://pubmed.ncbi.nlm.nih.gov/29264396
https://pubmed.ncbi.nlm.nih.gov/29264396
Autor:
Maira Moreno, Garcia, Rosa-Maria, Guéant-Rodriguez, Shabnam, Pooya, Patrick, Brachet, Jean-Marc, Alberto, Elise, Jeannesson, Fathia, Maskali, Naig, Gueguen, Pierre-Yves, Marie, Patrick, Lacolley, Markus, Herrmann, Yves, Juillière, Yves, Malthiery, Jean-Louis, Guéant
Publikováno v:
The Journal of pathology. 225(3)
Cardiomyopathies occur by mechanisms that involve inherited and acquired metabolic disorders. Both folate and vitamin B12 deficiencies are associated with left ventricular dysfunction, but mechanisms that underlie these associations are not known. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::615abc60f1c76b4b41034e20d3706228
https://pubmed.ncbi.nlm.nih.gov/21735445
https://pubmed.ncbi.nlm.nih.gov/21735445