Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Naifeng Qian"'
Autor:
Dale Frank, Robert J. Vosatka, Colum P. Walsh, Naifeng Qian, Diem Dao, Benjamin Tycko, Denise S. O'Keefe
Publikováno v:
Human Molecular Genetics. 7:597-608
Human chromosome 11p15.5 and distal mouse chromosome 7 include a megabase-scale chromosomal domain with multiple genes subject to parental imprinting. Here we describe mouse and human versions of a novel imprinted gene, IMPT1 , which lies between IPL
Autor:
Long Zhao, Qing Wang, Benjamin Tycko, Denise S. O'Keefe, Mark T. Keating, Naifeng Qian, Dale Frank, Colum P. Walsh, Diem Dao, Luwa Yuan
Publikováno v:
Human Molecular Genetics. 6:2021-2029
We searched for novel imprinted genes in a region of human chromosome 11p15.5, which contains several known imprinted genes. Here we describe the cloning and characterization of the IPL ( I mprinted in P lacenta and L iver) gene, which shows tissue-s
Publikováno v:
Human molecular genetics. 5(12)
There is increasing evidence for chromosomal domains containing multiple imprinted genes and for domain-wide disruption of imprinting in certain diseases. In a majority of Wilms' tumors (WTs) there is an abnormal bipaternal pattern of expression at t
Publikováno v:
The Journal of allergy and clinical immunology. 98(3)
Three known allergens of yellow jacket (Vespula vulgaris) venom are antigen 5, hyaluronidase, and phospholipase. Yellow jacket antigen 5 has been previously cloned and expressed in bacteria; it contains 204 amino acid residues, and it has 69% and 60%
Autor:
Ildiko M. Kovach, Palmer Taylor, Yuan Ping Pang, Naifeng Qian, Zoran Radić, Daniel M. Quinn, Ashima Saxena, Daniel C. Vellom, Alan P. Kozikowski, Bhupendra P. Doctor
Publikováno v:
Protein science : a publication of the Protein Society. 3(10)
Huperzine A, a potential agent for therapy in Alzheimer's disease and for prophylaxis of organophosphate toxicity, has recently been characterized as a reversible inhibitor of cholinesterases. To examine the specificity of this novel compound in more
Publikováno v:
FEBS letters. 349(1)
The channels connecting the active site of acetylcholinesterase (AChE) to the protein exterior were mapped by computational techniques in order to find potential exit routes for charged reaction products. 3.9% of the total volume of the AChE monomer
Autor:
Naifeng Qian, Ildiko M. Kovach
Publikováno v:
FEBS Letters. (2):263-266
Molecular modeling (GEMM 7.3) and molecular mechanics calculations (YETI V 5.3) using the X-ray coordinates for acetylcholinesterase (AChE) from Torpedo californica indicate electrostatic stabilization by the active site. Glu-199, of the developing p