Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Naiara Nieto-Rementeria"'
Autor:
María Dolores Boyano, Jolanta Idkowiak-Baldys, Aintzane Apraiz, Yusuf A. Hannun, Naiara Nieto-Rementeria, Aintzane Asumendi
4-(Hydroxyphenyl)retinamide (4-HPR) is a synthetic retinoid with a strong apoptotic effect towards different cancer cell lines in vitro, and it is currently tested in clinical trials. Increases of reactive oxygen species (ROS) and modulation of endog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39de56ba7317813a6b6574a22ea99d01
https://europepmc.org/articles/PMC3663831/
https://europepmc.org/articles/PMC3663831/
Autor:
Aintzane Asumendi, Aintzane Apraiz, María Dolores Boyano, Naiara Nieto-Rementeria, R. Izu, J. L. Diaz-Perez, Gorka Pérez-Yarza
Publikováno v:
The British journal of dermatology. 160(3)
Summary Background Bexarotene is the first synthetic retinoid X receptor-selective retinoid (rexinoid) approved for the treatment of cutaneous T-cell lymphoma (CTCL). However, little is known about the signalling pathways by which it exerts its antic
Autor:
María-Celia, Morales, Gorka, Pérez-Yarza, Naiara, Nieto-Rementeria, María-Dolores, Boyano, Muhialdin, Jangi, Rafael, Atencia, Aintzane, Asumendi
Publikováno v:
Anticancer research. 25(3B)
We have previously demonstrated that the synthetic retinoid N-(4-hydroxyphenyl) retinamide (4-HPR) induces the overproduction of reactive oxygen species (ROS) in human leukemia cells, which in turn triggers the intrinsic (mitochondrial) apoptotic pat