Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway

Autor: Lihua Cui, Caixia Li, Ye Shang, Dihua Li, Yuzhen Zhuo, Lei Yang, Naiqiang Cui, Yuhong Li, Shukun Zhang

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Pancreatic fibrosis is a pathological characteristic of chronic pancreatitis (CP) and pancreatic cancer. Chaihu Guizhi Ganjiang Decoction (CGGD) is a traditional Chinese medicine, which is widely used in the clinical treatment of digestive diseases.

Externí odkaz: https://doaj.org/article/75f0140d6e5e484f820694815bc90e3f

Diagnosis and treatment of exocrine pancreatic insufficiency in chronic pancreatitis: An international expert survey and case vignette study

Autor: Florence E.M. de Rijk, Charlotte L. van Veldhuisen, Marc G. Besselink, Jeanin E. van Hooft, Hjalmar C. van Santvoort, Erwin J.M. van Geenen, Peter Hegyi, J-Matthias Löhr, Juan E. Dominguez-Munoz, Pieter Jan F. de Jonge, Marco J. Bruno, Robert C. Verdonk, Massimo Falconi, Wen-Bin Zou, Trond Engjom, Chee Y. Ooi, Robert Sutton, Luca Frulloni, John Neoptolemos, Charles Wilcox, Vujasinovic Miroslav, Guru Trikudanathan, Zhuan Liao, Truls Hauge, Joachim Mössner, Chantal Hoge, Paul Fockens, Sven Mieog, Gabriele Capurso, Yunfeng Cui, Enrique de Madaria, Marius Distler, Ali Aghdassi, David C. Whitcomb, Kylie Russell, Georg Beyer, Lumír Kunovsky, Wilhelmus Kwanten, Andrea Kazemi Nava, Kevin Conlon, A.K. Siriwardena, Salvatore Paiella, Felipe Alconchel, Marco Vito Marino, Vincent E. de Meijer, Carlos Domingo, Jorg Kleeff, Aarti Lakshmanan, Michael Jen Lie Chu, Stefan Bouwense, Pueya Rashid Nashidengo, Perivoliotis Konstantinos, Edoardo Maria Muttillo, Garzali Ibrahim Umar, Maria Jesus Castro Santiago, Victor Lopez-Lopez, Francesco Torri, Moritz Schmelzle, Povilas Ignatavicius, Dennis Wicherts, Antonio Gomes, Nikolaos A. Machairas, Panagiotis I. Dorovinis, Alejandro Serrablo, Kjetil Soreide, Mohammad Rahbari, Michael Jen Jie Chu, Margarita Ptasnuka, Marius Petrulionis, Colin Byron Noel, Ernest Castro, Marcello Di Martino, Alfonso Recordare, Stefan Stättner, Fabio Ausania, Vera Hartman, Geert Roeyen, Viacheslav Egorov, Tomas Vanagas, Mohamed Ebrahim, Elena Arabadzhieva, Giuseppe Malleo, Liang Li, David Adams, Grzegorz Oracz, Reddy D. Nageshwar, Alexander Waldthaler, Atsushi Masamune, Asbjorn Mohr Drewes, Antonio Amodio, Temel Tirkes, Anshu Srivastava, Gregory J. Beilman, Zoltan Berger, Bjorn Lindkvist, Giulia Martina Cavestro, Cheryl Gariepy, Laszlo Czakó, Milena Di Leo, Vishal Sharma, Sundeep Lakhtakia, Surinder Singh Rana, Sinaed N. Duggan, Chang-Il Kwon, Anna Evans Phillips, Christopher E. Forsmark, Ferga C. Gleeson, Glen A. Lehman, William Greenhalf, Guido Costamagna, Christopher M. Halloran, Helmut Friess, Henrik Hojgaard Rasmussen, Tsukasa Ikeura, Ingfrid S. Haldorsen, Takao Itoi, Jacob R. Izbicki, John Windsor, Jakob Lykke Poulsen, Jens Brondum Frokjaer, Jose Larino-Noia, Dan Wang, Julio Iglesias Garcia, Evangelos Kalaitzakis, Kararzyna Wertheim-Tysarowska, Kensuke Kubota, Jessica Larusch, Markus M. Lerch, Liang-Hao Hu, Mert Erkan, Jorg D. Machicado, Marianna Arvanitakis, Markus W. Buchler, Marlon F. Levy, Melvin B. Heyman, Camilla Nojgaard, Mouen A. Khashab, Myriam Delhaye, Takeshi Ogura, Kazuichi Okazaki, Paula Ghaneh, Peter A. Banks, Pankaj Gupta, Georgios I. Papachristou, Patrick Michl, Philippe Levy, Aldis Pukitis, Raffaele Pezzilli, Ryan D. Baron, Stephen T. Amann, Sarah Jane Schwarzenberg, Shuiji Isaji, Soren Schou Olesen, Srdan Novovic, Steven J. Hughes, Steven L. Werlin, Tanja Gonska, Timothy B. Gardner, Mark D. Topazian, Frank Ulrich Weiss, Venakata S. Akshintala, Veronique D. Morinville, Vinciane Rebours, Aron Vincze, Vikesh K. Singh, Naiqiang Cui, Hong Zhang, Zhao-shen Li

Publikováno v: Pancreatology, 22(4), 457-465. ELSEVIER
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Pancreatology, 22(4), 457-465. ELSEVIER SCIENCE BV
Pancreatology, 22(4), 457-465. S. Karger AG
Pancreatology, 22, 457-465
Pancreatology, 22(4), 457-465. Elsevier
de Rijk, F E M, van Veldhuisen, C L, Besselink, M G, van Hooft, J E, van Santvoort, H C, van Geenen, E J M, Hegyi, P, Löhr, J M, Dominguez-Munoz, J E, de Jonge, P J F, Bruno, M J, Verdonk, R C, Novovic, S & for the Dutch Pancreatitis Study Group 2022, ' Diagnosis and treatment of exocrine pancreatic insufficiency in chronic pancreatitis : An international expert survey and case vignette study ', Pancreatology, vol. 22, no. 4, pp. 457-465 . https://doi.org/10.1016/j.pan.2022.03.013
Pancreatology, 22, 4, pp. 457-465
Dutch Pancreatitis Study Group 2022, ' Diagnosis and treatment of exocrine pancreatic insufficiency in chronic pancreatitis : An international expert survey and case vignette study ', Pancreatology, vol. 22, no. 4, pp. 457-465 . https://doi.org/10.1016/j.pan.2022.03.013

IntroductionDespite evidence-based guidelines, exocrine pancreatic insufficiency is frequently underdiagnosed and undertreated in patients with chronic pancreatitis. Therefore, the aim of this study is to provide insight into the current opinion and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9a10e78250b2d09088ca915d3865a2
https://hdl.handle.net/2066/252145

Saikosaponin D Attenuates Pancreatic Injury Through Suppressing the Apoptosis of Acinar Cell via Modulation of the MAPK Signaling Pathway

Autor: Yuzhen Zhuo, Caixia Li, Naiqiang Cui, Jialin Cui, Lei Yang, Lihua Cui, Shukun Zhang, Lan-Qiu Zhang

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology

Chronic pancreatitis (CP) is a progressive fibro-inflammatory syndrome. The damage of acinar cells is the main cause of inflammation and the activation of pancreatic stellate cells (PSCs), which can thereby possibly further aggravate the apoptosis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccce2e5b267053d7ba11ebd3a342522
https://www.frontiersin.org/articles/10.3389/fphar.2021.735079/full

Ginkgo biloba extract EGb 761–induced upregulation of LincRNA-p21 inhibits colorectal cancer metastasis by associating with EZH2

Autor: Tingting Liu, Naiqiang Cui, Zhongqiu Chai, Gang Wang, Junzhong Zhang, Bing Zhou

Publikováno v: Oncotarget

// Tingting Liu 1, 2 , Junzhong Zhang 2 , Zhongqiu Chai 3 , Gang Wang 4 , Naiqiang Cui 1 and Bing Zhou 1 1 Department of Integrated Chinese and Western Medicine Surgery, Tianjin University of Traditional Chinese Medicine, Tianjin, China 2 Department

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5628684e75380b20c36a4dd21647ee19
http://europepmc.org/articles/PMC5710951

FTY720 inhibits the activation of pancreatic stellate cells by promoting apoptosis and suppressing autophagy via the AMPK/mTOR pathway

Autor: Naiqiang Cui, Ge Gao, Caixia Li, Shukun Zhang, Yuzhen Zhuo, Lihua Cui, Lei Yang

Publikováno v: Life sciences. 217

Aims Pancreatic stellate cells (PSCs) play a critical role in the development of pancreatic fibrosis. Any agents that can affect PSC activation could become potential candidates for treating pancreatic fibrosis. FTY720 can attenuate chronic pancreati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233eae14a63580bfc83d7af483de4317
https://pubmed.ncbi.nlm.nih.gov/30550889