Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nai-xue Sun"'
Publikováno v:
Journal of Biomedical Research
Objective Retinopathy of prematurity is becoming obvious with the improvement of neonatal ambulance. However there is still not a good treatment. The present study is to observe the effect of 17 beta-estradiol (E2) on oxygen-induced retinopathy (OIR)
Publikováno v:
Acta Pharmacologica Sinica. 30:1625-1633
To investigate the effect of lentivirus-mediated integrin-linked kinase (ILK) RNA interference (RNAi) on human retinal Müller cells transdifferentiation into contractile myofibroblasts.A lentiviral vector expressing ILK-specific shRNA was constructe
Publikováno v:
Acta Pharmacologica Sinica. 30:413-423
The aim of the study was to evaluate the outcome of adenovirus-mediated p27KIP1 (Ad-p27) expression on wound healing after filtration surgery and to investigate the inhibition of cell proliferation induced by Ad-p27. We constructed the adenovirus rec
Publikováno v:
Acta Pharmacologica Sinica. 29:1021-1028
To determine the release characteristics of a 5-fluorouracil-loaded poly (lactic acid) disc (5-FU-PLA-DS) and the effect of sustained drug delivery on the success of glaucoma filtration surgery in rabbit eyes. A method of microspheres accumulated by
Publikováno v:
Journal of Nanjing Medical University. 21:262-267
Objective To investigate the role the lens dimensions played on the pathogenesis of primary angle-closure glaucoma. Methods 38 eyes of 20 patients with primary angle-closure glaucoma(PACG) and 35 eyes of 22 normal individuals without ocular abnormali
Publikováno v:
Investigative ophthalmologyvisual science. 54(1)
PURPOSE To investigate the potential antiproliferative effect of cyclin-dependent kinase inhibitor 1B (CDKN1B) overexpression in a rabbit model of glaucoma filtration surgery (GFS). METHODS The recombinant adenovector expressing exogenous CDKN1B was
Publikováno v:
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 48(5)
To investigate the effects of hydrogen peroxide (H2O2) on the barrier function and expression of tight junction protein in human retinal pigment epithelium (RPE) cells.Experimental study. The human RPE cell line (D407) were cultured and treated with
Publikováno v:
International journal of ophthalmology. 5(5)
To investigate the interfering effect of Y-27632, a ROCK-I selective inhibitor, on the signal transduction pathway of transforming growth factor-β1 (TGF-β1) in ocular Tenon capsule fibroblasts (OTFS) in vitro.After OTFS from passages 4 to 6 in vitr
Publikováno v:
Japanese journal of ophthalmology. 56(4)
Our aim was to explore the effects and mechanism of 17-alpha-estradiol (17α-E2) on oxygen-induced retinopathy (OIR) in a murine model. Newborn mice exposed to hyperoxia underwent subcutaneous injections of different doses of 17α-E2 from postnatal d
Autor:
Yao-Hua Sheng, Ke Yao, Zheng Zhong, Jian Ge, Xing-huai Sun, Jia-Liang Zhao, Yu-Min Li, Xiao-Xin Li, Nai-Xue Sun
Publikováno v:
BMC Ophthalmology
BMC Ophthalmology, Vol 11, Iss 1, p 23 (2011)
BMC Ophthalmology, Vol 11, Iss 1, p 23 (2011)
Background A noninferiority trial was conducted to evaluate the efficacy of a single evening dose of fixed-combination latanoprost 50 μg/mL and timolol 0.5 mg/mL (Xalacom®; LTFC), in Chinese patients with primary open-angle glaucoma (POAG) or ocula