Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nai-dy Wang"'
Publikováno v:
Cell and Tissue Research. 330:427-435
The CCAAT/enhancer-binding protein alpha (C/EBP alpha) is essential for maintaining the differentiated state of hepatocytes in vivo. C/EBP alpha activates albumin transcription and coordinates the expression of multiple ornithine cycle enzymes involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f76710930304d11bda4b7bbc4f557c
https://doi.org/10.1007/s00441-007-0505-4
https://doi.org/10.1007/s00441-007-0505-4
Autor:
Nai-dy Wang, Shing Chuan Hooi, Esther Wong, Sathivel Ponniah, Ee Hong Tan, Mirtha Laban, Aileen Wee
Publikováno v:
Cancer Research. 65:10330-10337
Hypoxia-inducible factor 1 (HIF-1) is the central mediator of cellular responses to low oxygen and has recently become an important therapeutic target for solid tumor therapy. Inhibition of HIF-1 is expected to result in the attenuation of hypoxia-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d3f2325b8a28f1ac6d1ea99077fa0d
https://doi.org/10.1158/0008-5472.can-04-4486
https://doi.org/10.1158/0008-5472.can-04-4486
Autor:
Gretchen J. Darlington, Milton J. Finegold, Nai-dy Wang, Dongcheul Kang, Humberto E. Soriano, M J Hicks, W Harrison
Publikováno v:
Hepatology. 27:392-401
The CCAAT/enhancer binding protein alpha (C/EBP alpha) binds to specific promoter sequences and directs transcription of many genes expressed in the liver. Overexpression of C/EBP alpha in established cell lines inhibits cell proliferation. Primary h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06b24091176c340b8c6f00fc05a79358
https://doi.org/10.1002/hep.510270212
https://doi.org/10.1002/hep.510270212
Autor:
Dong-Er Zhang, Nai-dy Wang, Daniel G. Tenen, Gretchen J. Darlington, Christopher J. Hetherington, Pu Zhang
Publikováno v:
Proceedings of the National Academy of Sciences. 94:569-574
Transcription factors are master regulatory switches of differentiation, including the development of specific hematopoietic lineages from stem cells. Here we show that mice with targeted disruption of the CCAAT enhancer binding protein α gene (C/EB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e663b712ce2ed1336621597c3a4068ff
https://doi.org/10.1073/pnas.94.2.569
https://doi.org/10.1073/pnas.94.2.569
Autor:
L. Ranee Taylor, Allan Bradley, Milton J. Finegold, Margaret Wilde, Nai-dy Wang, Ching N. Ou, Sandy V. Abdelsayed, Deborah R. Wilson, Gretchen J. Darlington
Publikováno v:
Science. 269:1108-1112
Mice homozygous for the targeted deletion of the c/ebp alpha gene, which expresses the CCAAT/enhancer-binding protein alpha (C/EBP alpha), did not store hepatic glycogen and died from hypoglycemia within 8 hours after birth. In these mutant mice, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46813360d3a1c3410a84d8d29ee8c026
https://doi.org/10.1126/science.7652557
https://doi.org/10.1126/science.7652557
Publikováno v:
Genomics. 14:891-896
Using the human/hamster cell line UCTP2A-3, we have generated and isolated three hybrids, each containing a novel human chromosome 3p break. All chromosome 3 materials distal to the breaks were lost. Two of the breakpoints were produced using aphidic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8d0fc116a77b7ccd113d442d2090a6
https://doi.org/10.1016/s0888-7543(05)80110-7
https://doi.org/10.1016/s0888-7543(05)80110-7
Autor:
Franco Recchia, Patricia Green, Nai dy Wang, David Ginzinger, Wanguo Liu, Scott E. Smith, David I. Smith, Kathy Carolyn, William Golembieski, Harry A. Drabkin
Publikováno v:
Genomics. 11:179-187
A total of 5700 human chromosome 3-specific cosmid clones was isolated from a series of cosmid libraries constructed from somatic cell hybrids whose only human component was an entire chromosome 3 or a chromosome 3 containing an interstitial deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78110a786cab6fd23f946557294fdb38
https://doi.org/10.1016/0888-7543(91)90116-v
https://doi.org/10.1016/0888-7543(91)90116-v
Publikováno v:
Biotechnology letters. 29(2)
FAM-labeled oligo dT (FAMdT) was utilized as a means to gauge efficient transfection of small nucleic acids into mouse embryonic stem cell (mESC) colonies. Using colonies grown overnight, transfection was restricted largely to the periphery of the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab6d8413d265933ed40e171abf053e2
https://pubmed.ncbi.nlm.nih.gov/17091374
https://pubmed.ncbi.nlm.nih.gov/17091374
Autor:
M. Negri, Nai Dy Wang, David I. Smith, Peggy McKie-Bell, Iúri Drumond Louro, Martin J. Smith, Jochen Schütte, Maria Rosa Bani, Miriam Wagner, Songrong Ren, Bertram Opalka, Rudolph A. Herbst, J. Michael Ruppert, Walter Bardenheuer, William E. Grizzle, David T. Redden, Barry Zochodne, Jeffrey M. Trent, Yaacov Ben-David
Publikováno v:
Oncogene. 19(11)
Gene amplification is frequently present in human tumors, although specific target genes relevant to many amplified loci remain unidentified. An expression cloning assay enabled identification of a candidate oncogene derived from human chromosome 3p1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0f3bd79d65f4640243320edb7a23c4
https://pubmed.ncbi.nlm.nih.gov/10723133
https://pubmed.ncbi.nlm.nih.gov/10723133
Publikováno v:
Genomics. 17(2)
The constitutive 3p14.2 fragile site is the most highly inducible fragile site in the human genome. This locus may predispose chromosome 3 to specific losses due to the deletions and translocations that have been associated with several malignancies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2157c9d457a7645336f7a1884818dfb
https://pubmed.ncbi.nlm.nih.gov/8406484
https://pubmed.ncbi.nlm.nih.gov/8406484