Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nai-Yun Sun"'
Autor:
Andrew J. H. Sedlack, Samual J. Hatfield, Suresh Kumar, Yasuhiro Arakawa, Nitin Roper, Nai-Yun Sun, Naris Nilubol, Katja Kiseljak-Vassiliades, Chuong D. Hoang, Emily K. Bergsland, Jonathan M. Hernandez, Yves Pommier, Jaydira del Rivero
Publikováno v:
Cancers, Vol 15, Iss 11, p 2873 (2023)
Adrenocortical cancer is an aggressive endocrine malignancy with an incidence of 0.72 to 1.02 per million people/year, and a very poor prognosis with a five-year survival rate of 22%. As an orphan disease, clinical data are scarce, meaning that drug
Externí odkaz:
https://doaj.org/article/6897a709043c4babbac9aab30d3acb29
Autor:
Nai-Yun Sun, Muh-Hwa Yang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Metabolic reprogramming and epithelial-mesenchymal plasticity are both hallmarks of the adaptation of cancer cells for tumor growth and progression. For metabolic changes, cancer cells alter metabolism by utilizing glucose, lipids, and amino acids to
Externí odkaz:
https://doaj.org/article/1398eef0d0844ba69dfdb04d1472aafc
Autor:
Yu-Yun Shao, Nai-Yun Sun, Yung-Ming Jeng, Yao-Ming Wu, Chiun Hsu, Chih-Hung Hsu, Hey-Chi Hsu, Ann-Lii Cheng, Zhong-Zhe Lin
Publikováno v:
Cells, Vol 10, Iss 7, p 1698 (2021)
Background: The kinesin Eg5, a mitosis-associated protein, is overexpressed in many cancers. Here we explored the clinical significance of Eg5 in hepatocellular carcinoma (HCC). Methods: HCC tissues from surgical resection were collected. Total RNA w
Externí odkaz:
https://doaj.org/article/0d27aa88f52645c785868aaa843813d5
Autor:
Nai-Yun Sun, Yu-Li Chen, Wen-Yih Wu, Han-Wei Lin, Ying-Cheng Chiang, Chi-Fang Chang, Yi-Jou Tai, Heng-Cheng Hsu, Chi-An Chen, Wei-Zen Sun, Wen-Fang Cheng
Publikováno v:
Cancers, Vol 11, Iss 9, p 1400 (2019)
The immuno-inhibitory checkpoint PD-L1, regulated by tumor cells and antigen-presenting cells (APCs), dampened the activation of T cells from the PD-1/PD-L1 axis. PD-L1-expressing APCs rather than tumor cells demonstrated the essential anti-tumor eff
Externí odkaz:
https://doaj.org/article/0364a44c00394a7f9ee1b1086a8f36e1
Autor:
Yu-Li Chen, Han-Wei Lin, Nai-Yun Sun, Jr-Chi Yie, Hsueh-Chih Hung, Chi-An Chen, Wei-Zen Sun, Wen-Fang Cheng
Publikováno v:
Cancers, Vol 11, Iss 5, p 617 (2019)
The life span of dendritic cells (DCs) can become short following induced activation, which is associated with metabolic transition due to the regulation of mechanistic target of rapamycin (mTOR). The purpose of this study was to investigate the pote
Externí odkaz:
https://doaj.org/article/fd2e78f625074687a0c8060375e7a290
Autor:
Nai-Yun Sun, 孫乃云
107
I determined the antitumor effects and possible mechanisms of an antigen-specific DNA vaccine combined with PD-1 or CTLA-4 blockade. Using the HPV16 E6/E7+ syngeneic mouse tumor model, we investigated whether anti-CTLA-4 antibody (Ab) or ant
I determined the antitumor effects and possible mechanisms of an antigen-specific DNA vaccine combined with PD-1 or CTLA-4 blockade. Using the HPV16 E6/E7+ syngeneic mouse tumor model, we investigated whether anti-CTLA-4 antibody (Ab) or ant
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/cnu6u6
Autor:
Chiun Hsu, Zhong Zhe Lin, Ann-Lii Cheng, Hey Chi Hsu, Yung-Ming Jeng, Chih-Hung Hsu, Yu-Yun Shao, Yao-Ming Wu, Nai Yun Sun
Publikováno v:
Cells
Cells; Volume 10; Issue 7; Pages: 1698
Cells, Vol 10, Iss 1698, p 1698 (2021)
Cells; Volume 10; Issue 7; Pages: 1698
Cells, Vol 10, Iss 1698, p 1698 (2021)
Background: The kinesin Eg5, a mitosis-associated protein, is overexpressed in many cancers. Here we explored the clinical significance of Eg5 in hepatocellular carcinoma (HCC). Methods: HCC tissues from surgical resection were collected. Total RNA w
Autor:
Yu-Yun Shao, Nai-Yun Sun, Yung-Ming Jeng, Yao-Ming Wu, Chiun Hsu, Chih-Hung Hsu, Hey-Chi Hsu, Ann-Lii Cheng, Zhong-Zhe Lin
Background: The kinesin Eg5, a mitosis-associated protein, is overexpressed in many cancers. Here we explored the clinical significance of Eg5 in HCC.Methods: HCC tissues from surgical resection were collected. Total RNA was prepared from tumorous an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac2a6e44b016906f59272facb2790f33
https://doi.org/10.21203/rs.3.rs-92166/v1
https://doi.org/10.21203/rs.3.rs-92166/v1
Autor:
Chi-An Chen, Wei-Zen Sun, Wen-Fang Cheng, Nai-Yun Sun, Ying-Cheng Chiang, Ming-Cheng Chang, Yu-Li Chen, Han-Wei Lin
Publikováno v:
Cancer Letters. 425:152-163
As a tumor antigen, mesothelin (MSLN) can be identified in various malignancies. MSLN is potential for antigen-specific cancer vaccines. We generated a novel chimeric DNA vaccine using antigen-specific connective tissue growth factor lined with MSLN
Autor:
Yi-Jou Tai, Chi-An Chen, Nai-Yun Sun, Ying-Cheng Chiang, Wen-Fang Cheng, Heng-Cheng Hsu, Han-Wei Lin, Yu-Li Chen, Wei-Zen Sun, Chi-Fang Chang, Wen-Yih Wu
Publikováno v:
Cancers
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1400 (2019)
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1400 (2019)
The immuno-inhibitory checkpoint PD-L1, regulated by tumor cells and antigen-presenting cells (APCs), dampened the activation of T cells from the PD-1/PD-L1 axis. PD-L1-expressing APCs rather than tumor cells demonstrated the essential anti-tumor eff