Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Nai-Kui Liu"'
Autor:
Wenrui Qu, Xiangbing Wu, Wei Wu, Ying Wang, Yan Sun, Lingxiao Deng, Melissa Walker, Chen Chen, Heqiao Dai, Qi Han, Ying Ding, Yongzhi Xia, George Smith, Rui Li, Nai-Kui Liu, Xiao-Ming Xu
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 5, Pp 1467-1482 (2025)
Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties. A the Food and Drug Administration-approved Phase I clinical trial
Externí odkaz:
https://doaj.org/article/668ac4c651f44862aab98702c78b221a
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 836-844 (2025)
Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes followi
Externí odkaz:
https://doaj.org/article/029cdaa92749490fb622269f0d30e083
Autor:
Nai-Kui Liu, Ling-Xiao Deng, Miao Wang, Qing-Bo Lu, Chunyan Wang, Xiangbing Wu, Wei Wu, Ying Wang, Wenrui Qu, Qi Han, Yongzhi Xia, Baylen Ravenscraft, Jin-Lian Li, Si-Wei You, Peter Wipf, Xianlin Han, Xiao-Ming Xu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-16 (2022)
Abstract Alterations in phospholipids have long been associated with spinal cord injury (SCI). However, their specific roles and signaling cascades in mediating cell death and tissue repair remain unclear. Here we investigated whether alterations of
Externí odkaz:
https://doaj.org/article/25441a47b06f41fe8fc1e177c855cf32
Autor:
Wei Wu, Tyler Nguyen, Josue D. Ordaz, Yiping Zhang, Nai-Kui Liu, Xinhua Hu, Yuxiang Liu, Xingjie Ping, Qi Han, Xiangbing Wu, Wenrui Qu, Sujuan Gao, Christopher B. Shields, Xiaoming Jin, Xiao-Ming Xu
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
Understanding the reorganization of neural circuits spared after spinal cord injury in the motor cortex and spinal cord would provide insights for developing therapeutics. Using optogenetic mapping, we demonstrated a transhemispheric recruitment of n
Externí odkaz:
https://doaj.org/article/375a8c55056e4201b03d1ecc855f2f1c
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 186-191 (2021)
Biomaterial bridging provides physical substrates to guide axonal growth across the lesion. To achieve efficient directional guidance, combinatory strategies using permissive matrix, cells and trophic factors are necessary. In the present study, we e
Externí odkaz:
https://doaj.org/article/9a78e670c4404ef48095ebfed57f7e5d
Autor:
Qi Han, Josue D. Ordaz, Nai-Kui Liu, Zoe Richardson, Wei Wu, Yongzhi Xia, Wenrui Qu, Ying Wang, Heqiao Dai, Yi Ping Zhang, Christopher B. Shields, George M. Smith, Xiao-Ming Xu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Neurotrophin-3 (NT-3) plays a key role in the growth, development, and function of the nervous system. Here the authors show that NT-3-induced propriospino-motoneuron circuit reorganization is critical for locomotor recovery in mice following spinal
Externí odkaz:
https://doaj.org/article/82507d8a067d4b81923c7112757684bb
Autor:
Ying Wang, Wei Wu, Xiangbing Wu, Yan Sun, Yi P Zhang, Ling-Xiao Deng, Melissa Jane Walker, Wenrui Qu, Chen Chen, Nai-Kui Liu, Qi Han, Heqiao Dai, Lisa BE Shields, Christopher B Shields, Dale R Sengelaub, Kathryn J Jones, George M Smith, Xiao-Ming Xu
Publikováno v:
eLife, Vol 7 (2018)
Retrogradely-transported neurotrophin signaling plays an important role in regulating neural circuit specificity. Here we investigated whether targeted delivery of neurotrophin-3 (NT-3) to lumbar motoneurons (MNs) caudal to a thoracic (T10) contusive
Externí odkaz:
https://doaj.org/article/8a30e0b29f914c39a805040cd8856858
Autor:
Jian-Guo Hu, Xiao-Fei Wang, Ling-Xiao Deng, Nai-Kui Liu, Xiang Gao, Jinhui Chen, Feng C. Zhou, Xiao-Ming Xu Ph.D
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Oligodendrocyte (OL) replacement can be a promising strategy for spinal cord injury (SCI) repair. However, the poor posttransplantation survival and inhibitory properties to axonal regeneration are two major challenges that limit their use as donor c
Externí odkaz:
https://doaj.org/article/f67e42eaf565420aba3061208ed13436
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 2, Pp 0-0 (2016)
Externí odkaz:
https://doaj.org/article/86dd20979af04432879f1428c254d20c
Autor:
Chandler L Walker, Melissa J Walker, Nai-Kui Liu, Emelie C Risberg, Xiang Gao, Jinhui Chen, Xiao-Ming Xu
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30012 (2012)
Secondary damage following primary spinal cord injury extends pathology beyond the site of initial trauma, and effective management is imperative for maximizing anatomical and functional recovery. Bisperoxovanadium compounds have proven neuroprotecti
Externí odkaz:
https://doaj.org/article/60a8c087a4a247f692a7c3d4b3325539