Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nai-Chuan Chang"'
Autor:
Yu-Feng Huang, Yen-Ju Chen, Tan-Chi Fan, Nai-Chuan Chang, Yi-Jie Chen, Mohit K. Midha, Tzu-Han Chen, Hsiao-Hsiang Yang, Yu-Tai Wang, Alice L. Yu, Kuo-Ping Chiu
Publikováno v:
BMC Medical Genomics, Vol 11, Iss S1, Pp 33-41 (2018)
Abstract Background Cell-free circulating DNA (cfDNA) is becoming a useful biopsy for noninvasive diagnosis of diseases. Microbial sequences in plasma cfDNA may provide important information to improve prognosis and treatment. We have developed a str
Externí odkaz:
https://doaj.org/article/9157e916327a4fc2b35e8b4eca06f1a1
Autor:
Tan-Chi Fan, Nai-Chuan Chang, Jyh-Cherng Yu, Hui Ling Yeo, John Yu, Ming-Yi Ho, Alice L. Yu, Wen-Der Lin, Huan-Ming Hsu
Publikováno v:
Cancer Letters. 434:184-195
GFRA1 and RET are overexpressed in estrogen receptor (ER)-positive breast cancers. Binding of GDNF to GFRA1 triggers RET signaling leading to ER phosphorylation and estrogen-independent transcriptional activation of ER-dependent genes. Both GFRA1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7bb605673dc71085d767c77a7b132b
https://doi.org/10.1016/j.canlet.2018.07.026
https://doi.org/10.1016/j.canlet.2018.07.026
Autor:
Jen-Chine Wu, Hui-Ling Yeo, Ruey-Jen Lin, Tai-Yu Lai, Nai-Chuan Chang, Guo-Shiou Liao, Ching-Liang Ho, I-Ju Chen, Alice L. Yu, Andy C Lee
Publikováno v:
Cell Death Discovery, Vol 5, Iss 1, Pp 1-12 (2019)
Cell death discovery, vol 5, iss 1
Cell Death Discovery
Cell death discovery, vol 5, iss 1
Cell Death Discovery
FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7857a1a0901af7a99530e224fc752e3d
https://doi.org/10.1038/s41420-019-0145-y
https://doi.org/10.1038/s41420-019-0145-y
Autor:
Nai-Chuan Chang, Andy C Lee, I-Ju Chen, Hui Ming Yu, John Yu, Te-Wei Lee, Alice L. Yu, Han-Chung Wu, Sheng-Hung Wang, Ya-Jen Chang, Jyh-Cherng Yu
Publikováno v:
Biomaterials. 94:31-44
It is more challenging to design peptide drugs than small molecules through molecular docking and in silico analysis. Here, we developed a structure-based approach with various computational and analytical techniques to optimize cancer-targeting pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43946aeb23e71f2d1334507eca5001f
https://doi.org/10.1016/j.biomaterials.2016.03.050
https://doi.org/10.1016/j.biomaterials.2016.03.050
Autor:
Yu-Feng Huang, Nai-Chuan Chang, Mohit K. Midha, Alice L. Yu, Chen-Yang Shen, Kuo Ping Chiu, King-Jen Chang, Tan-Chi Fan, Yu-Tai Wang, Chien-Jen Chen, Tzu-Han Chen, Hsiao-Hsiang Yang, Wen-Hung Kuo
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2089, p 2089 (2020)
Cancers, vol 12, iss 8
Volume 12
Issue 8
Cancers, Vol 12, Iss 2089, p 2089 (2020)
Cancers, vol 12, iss 8
Early onset breast cancer (EOBC), diagnosed at age ~40 or younger, is associated with a poorer prognosis and higher mortality rate compared to breast cancer diagnosed at age 50 or older. EOBC poses a serious threat to public health and requires in-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e3bb39421cd12246a7b1d706b01bdb
https://doi.org/10.3390/cancers12082089
https://doi.org/10.3390/cancers12082089
Autor:
Nai-Chuan Chang, Margaret Dah-Tsyr Chang, Chein‐Hung Chen, John Yu, Kowa Chen, Eric Sheng‐Wen Chen, Jen-Chine Wu, Jung-Tung Hung, Alice L. Yu, Ming-Yi Ho, Ruey-Jen Lin, Tan-Chi Fan, Wen-Der Lin, Guo-Shiou Liao, Jyh-Cherng Yu, Hui Ling Yeo
Publikováno v:
International Journal of Cancer
ST3Gal1 is a key sialyltransferase which adds α2,3‐linked sialic acid to substrates and generates core 1 O‐glycan structure. Upregulation of ST3Gal1 has been associated with worse prognosis of breast cancer patients. However, the protein substra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf1f532a7078c6708d0431dd43c1161
https://pubmed.ncbi.nlm.nih.gov/30252131
https://pubmed.ncbi.nlm.nih.gov/30252131
Publikováno v:
Cancer Research. 71:1366-1366
We have recently developed practical software programs for optimization of cancer targeting peptides, including combinatorial construction of 3D peptide library (Buildpep), binding pocket analyzer (PscanMS) and high accuracy protein-ligand scoring pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c628e8ba476ee4e1549c69e3583ce97
https://doi.org/10.1158/1538-7445.am2011-1366
https://doi.org/10.1158/1538-7445.am2011-1366