Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Nai Ki Mak"'
Autor:
Yuehong Shen, Yuling Chen, Yuntao Lin, Yicun Li, Pengfei Liu, Biru Zhang, Yufan Wang, King-Chi Chan, Nai-Ki Mak, Michael Kahn, Robert Z. Qi, Hongyu Yang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-11 (2023)
Abstract In oral squamous cell carcinoma (OSCC), a highly aggressive and frequently lethal malignancy, the role and action mechanism of the microtubule regulatory protein CDK5RAP2 have not been fully understood. Here, we show that CDK5RAP2 is highly
Externí odkaz:
https://doaj.org/article/22f3678e7deb4de69dfd33dd0e53ae80
Autor:
Ho-Fai Chau, Yue Wu, Wan-Yiu Fok, Waygen Thor, William Chi-Shing Cho, Ping’an Ma, Jun Lin, Nai-Ki Mak, Jean-Claude G. Bünzli, Lijun Jiang, Nicholas J. Long, Hong Lok Lung, Ka-Leung Wong
Publikováno v:
JACS Au, Vol 1, Iss 7, Pp 1034-1043 (2021)
Externí odkaz:
https://doaj.org/article/eb98c4f5f2994b63bd3fdb0401a0dedb
Publikováno v:
ADMET and DMPK, Vol 7, Iss 1, Pp 22-43 (2019)
Oseltamivir phosphate (OP, Tamiflu®) is a widely used prodrug for the treatment of influenza viral infections. Orally administered OP is rapidly hydrolyzed by the carboxylesterases in animals to oseltamivir carboxylate (OC), a potent influenza virus
Externí odkaz:
https://doaj.org/article/38e0609ec57d47138c5c2c97df1c3b11
Autor:
Yue Liu, Ka Sin Lui, Zuodong Ye, Tsz Yan Fung, Luo Chen, Ping Yiu Sit, Chin Yu Leung, Nai Ki Mak, Ka-Leung Wong, Hong Lok Lung, Yoshimasa Tanaka, Allen Ka Loon Cheung
Publikováno v:
Theranostics. 13:458-471
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d76f7b26c363f2b1ac52abfa178584e
https://doi.org/10.7150/thno.78395
https://doi.org/10.7150/thno.78395
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Nasopharyngeal carcinoma (NPC) is consistently associated with Epstein-Barr virus (EBV) infection in regions in which it is endemic, including Southern China and Southeast Asia. The high mortality rates of NPC patients with advanced and recurrent dis
Externí odkaz:
https://doaj.org/article/abe559c8c29f415c818dc9d53fff1cec
Autor:
Wan-Yiu Fok, Jun Lin, Nicholas J. Long, Nai Ki Mak, Yue Wu, Waygen Thor, Lijun Jiang, Ping'an Ma, Ho-Fai Chau, Hong Lok Lung, Ka-Leung Wong, William C. Cho, Jean-Claude G. Bünzli
Publikováno v:
JACS Au
JACS Au, Vol 1, Iss 7, Pp 1034-1043 (2021)
JACS Au, Vol 1, Iss 7, Pp 1034-1043 (2021)
A lanthanide-based peptide-directed bioprobe LnP19 (Ln = Eu or Yb) is designed as an impressive example of a small molecule-based dual-functional probe for the EBV oncoprotein LMP1. The peptide P19 (Pra-KAhx-K-LDLALK-FWLY-K-IVMSDKW-K-RrRK) is designe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0014832c3871814badaf59c60b1854dd
https://doi.org/10.1021/jacsau.1c00187
https://doi.org/10.1021/jacsau.1c00187
Autor:
Luo Chen, Yiu Chun Chiang, Lai Sheung Chan, Wai Yin Chau, Maria Li Lung, Michael Kahn, Kwok Wai Lo, Nai Ki Mak, Hong Lok Lung
Publikováno v:
Cancers; Volume 14; Issue 13; Pages: 3125
Nasopharyngeal carcinoma (NPC) is an Epstein–Barr virus (EBV)-associated malignancy ranking as the 23rd most common cancer globally, while its incidence rate ranked the 9th in southeast Asia. Tumor metastasis is the dominant cause for treatment fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee302a70ed73efcb13a5116da133e87
https://pubmed.ncbi.nlm.nih.gov/35804897
https://pubmed.ncbi.nlm.nih.gov/35804897
Autor:
Wai Yin Chau, Chung Hung Fong, On Ying Man, Wai Ho Shuen, Maria Li Lung, Nai Ki Mak, Hong Lok Lung, Rebecca Kan, Sai Wah Tsao
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
We and others have previously shown that the canonical nuclear factor kappa-B (NF-κB) pathway is essential to nasopharyngeal carcinoma (NPC) tumor development and angiogenesis, suggesting that the NF-κB pathway, including its upstream modulators an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d29315513449c4add3fa64b080a8d7
http://link.springer.com/article/10.1038/s41598-019-48590-7
http://link.springer.com/article/10.1038/s41598-019-48590-7
Publikováno v:
ADMET and DMPK
Volume 7
Issue 1
ADMET and DMPK, Vol 7, Iss 1, Pp 22-43 (2019)
Volume 7
Issue 1
ADMET and DMPK, Vol 7, Iss 1, Pp 22-43 (2019)
Oseltamivir phosphate (OP, Tamiflu®) is a widely used prodrug for the treatment of influenza viral infections. Orally administered OP is rapidly hydrolyzed by the carboxylesterases in animals to oseltamivir carboxylate (OC), a potent influenza virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68162f60b4d0ad85f84161b4e259c2a
https://doi.org/10.5599/admet.628
https://doi.org/10.5599/admet.628
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82294 (2013)
Angiogenesis is a key step for tumour growth and metastasis, and anti-angiogenesis has been proposed as an important strategy for cancer therapy. Tryptanthrin is a weakly basic alkaloid isolated from the dried roots of medicinal indigo plants and has
Externí odkaz:
https://doaj.org/article/753d21d9816045bfa38318a20440da14