Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nahum Smith"'
Autor:
Mariame Diabate, Muhtadi M Islam, Gregory Nagy, Tapahsama Banerjee, Shruti Dhar, Nahum Smith, Aleksandra I Adamovich, Lea M Starita, Jeffrey D Parvin
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010739 (2023)
Single nucleotide variants are the most frequent type of sequence changes detected in the genome and these are frequently variants of uncertain significance (VUS). VUS are changes in DNA for which disease risk association is unknown. Thus, methods th
Externí odkaz:
https://doaj.org/article/5e5fff7cb983421cac075a75fd103b1c
Autor:
Gregory Nagy, Mariame Diabate, Tapahsama Banerjee, Aleksandra I. Adamovich, Nahum Smith, Hyeongseon Jeon, Shruti Dhar, Wenfang Liu, Katherine Burgess, Dongjun Chung, Lea M. Starita, Jeffrey D. Parvin
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/d91b14e5d5a1447cb257877be7e81276
Autor:
Sean C. Murphy, Andrew S. Ishizuka, Zachary P. Billman, Tayla M. Olsen, Annette M. Seilie, Ming Chang, Nahum Smith, Vorada Chuenchob, Sumana Chakravarty, B. Kim Lee Sim, Stefan H. I. Kappe, Stephen L. Hoffman, Robert A. Seder
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-7 (2018)
Abstract Background Plasmodium 18S rRNA is a biomarker used to monitor blood-stage infections in malaria clinical trials. Plasmodium sporozoites also express this biomarker, and there is conflicting evidence about how long sporozoite-derived 18S rRNA
Externí odkaz:
https://doaj.org/article/3c8722635273467ebc922afacc5a82ce
Autor:
Kaitlyn A Barrow, Sarah Heidl, Elisabeth Brandstetter, Deborah A. Nickerson, Rachel E. Geyer, Sanjay Srivatsan, Eric Q. Konnick, Nahum Smith, Mark J. Rieder, Sriram Kosuri, Helen Y. Chu, Lea M. Starita, Misja Ilcisin, Shari Cho, L.M. Rich, Luis Gamboa, Denise J. McCulloch, Jay Shendure, Jeremy Stone, Jordan Opsahl, Ashley E. Kim, Caitlin R Wolf, Christina M. Lockwood, Peter D Han, Melissa Truong, Trevor Bedford, Wei Chen, Evan McDermot, Beth Martin, Sarah L Sohlberg, Brian Pfau, Jase Gehring, Katrina van Raay, Jason S Debley, Weizhi Zhong
Publikováno v:
Clinical Chemistry
Background The urgent need for massively scaled clinical testing for SARS-CoV-2, along with global shortages of critical reagents and supplies, has necessitated development of streamlined laboratory testing protocols. Conventional nucleic acid testin
Autor:
Aleksandra I. Adamovich, Mariame Diabate, Tapahsama Banerjee, Gregory Nagy, Nahum Smith, Kathryn Duncan, Erika Mendoza Mendoza, Gisselle Prida, Michael A. Freitas, Lea M. Starita, Jeffrey D. Parvin
Publikováno v:
Am J Hum Genet
Pathogenic variants in BRCA1 are associated with a greatly increased risk of hereditary breast and ovarian cancer (HBOC). With the increased availability and affordability of genetic testing, many individuals have been identified with BRCA1 variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc3f59f9524c541d9bf6b547e6cf703
https://europepmc.org/articles/PMC9069074/
https://europepmc.org/articles/PMC9069074/
Autor:
Rachel E. Geyer, Sanjay Srivatsan, Sarah L Sohlberg, Kaitlyn A Barrow, Luis Gamboa, Elisabeth Brandstetter, Jordan Opsahl, Deborah A. Nickerson, Brian Pfau, Seattle Flu Study Investigators, Nahum Smith, Sarah Heidl, Helen Y. Chu, Mark J. Rieder, L.M. Rich, Jason S Debley, Peter D Han, Eric Q. Konnick, Weizhi Zhong, Beth Martin, Sriram Kosuri, Wei Chen, Lea M. Starita, Misja Ilcisin, Shari Cho, Christina M. Lockwood, Jay Shendure, Melissa Truong, Ashley E. Kim, Trevor Bedford, Caitlin R Wolf, Evan McDermot, Denise J. McCulloch, Jeremy Stone, Jase Gehring, Katrina van Raay
Structured AbstractBackgroundThe urgent need for massively scaled clinical testing for SARS-CoV-2, along with global shortages of critical reagents and supplies, has necessitated development of streamlined laboratory testing protocols. Conventional n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dfb95e5ad7b58e0818055e9f224638a
https://doi.org/10.1101/2020.04.22.056283
https://doi.org/10.1101/2020.04.22.056283
Autor:
Nahum Smith, Ronald J. Hause, Eric Q. Konnick, Colin C. Pritchard, Stephen J. Salipante, Adam Waalkes, Kelsi Penewit, Jennifer A. Hempelmann
Publikováno v:
Clinical Chemistry. 64:950-958
BACKGROUND Microsatellite instability (MSI) is an emerging actionable phenotype in oncology that informs tumor response to immune checkpoint pathway immunotherapy. However, there remains a need for MSI diagnostics that are low cost, highly accurate,
Autor:
Michael Aidoo, Sean C. Murphy, Nahum Smith, Annette M. Seilie, Camelia Herman, Venkatachalam Udhayakumar, Mateusz M. Plucinski, Naomi W. Lucchi, Dragan Ljolje, Eric Rogier, Kurtis R. Cruz, Eric S. Halsey, Sophie Jones, Rafael Dimbu, Filomeno Fortes
Background Detection of Plasmodium antigens provides evidence of malaria infection status and is the basis for most malaria diagnosis. Methods We developed a sensitive bead-based multiplex assay for laboratory use, which simultaneously detects pan-Pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905532b0dca6381799a39e31fb051a42
https://europepmc.org/articles/PMC6325347/
https://europepmc.org/articles/PMC6325347/
Autor:
Sean C. Murphy, Pedro Rafael Dimbu, Nahum Smith, Kurtis R. Cruz, Eric S. Halsey, Mateusz M. Plucinski, Filomeno Fortes, Annette M. Seilie, Eric Rogier, Michael Aidoo
Publikováno v:
Am J Trop Med Hyg
Low-density malaria infections are a source of human morbidity in endemic settings and potentially contribute to ongoing malaria transmission. Conventional rapid diagnostic tests (RDTs) were designed to detect clinically relevant parasite and antigen