Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Nahum Puebla-Osorio"'
Autor:
Yun Hu, Alexey Revenko, Hampartsoum Barsoumian, Genevieve Bertolet, Natalie Wall Fowlkes, Hadi Maazi, Morgan Maureen Green, Kewen He, Duygu Sezen, Tiffany A. Voss, Claudia S Kettlun Leyton, Fatemeh Masrorpour, Zahid Rafiq, Nahum Puebla-Osorio, Carola Leuschner, Robert MacLeod, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background The combination of radiotherapy and immunotherapy (immunoradiotherapy) has been increasingly used for treating a wide range of cancers. However, some tumors are resistant to immunoradiotherapy. We have previously shown that MER pr
Externí odkaz:
https://doaj.org/article/bfe32f32799d4d64804e7e64eb090fe4
Autor:
James Welsh, Vittorio Cristini, Mark Wasley, Joylise Mitchell, Nahum Puebla-Osorio, Ailing Huang, Sara Nizzero, Gitika Srivastava, Thomas Riad, Papa Diogop Ndiaye, Mariam Gachechiladze, Philipp Oertle, Tobias Appenzeller, Marko Loparic, Marija Plodinec
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/68c3759873d84ba0a9b2e01d1e691d6a
Autor:
Hampartsoum B. Barsoumian, Jerry Hsu, Selene Nanez, Yun Hu, Ethan Y. Hsu, Thomas S. Riad, Nahum Puebla-Osorio, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Immuno, Vol 3, Iss 1, Pp 74-85 (2023)
Since the momentous discovery of X-rays, high-dose radiotherapy (H-XRT) has been a cornerstone for combating cancer. The high-energy electromagnetic waves induce direct damage to tumor-cells’ DNA, thereby halting cell growth and proliferation, and
Externí odkaz:
https://doaj.org/article/d82617074f4e4d829e76cb19dd1dd2bf
Autor:
Yun Hu, Sébastien Paris, Narayan Sahoo, Genevieve Bertolet, Qi Wang, Qianxia Wang, Hampartsoum B. Barsoumian, Jordan Da Silva, Ailing Huang, Denaha J. Doss, David P. Pollock, Ethan Hsu, Nanez Selene, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Shonik Ganjoo, Carola Leuschner, Jordan T. Pietz, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
The combination of radiation therapy (RT) and immunotherapy has emerged as a promising treatment option in oncology. Historically, x-ray radiation (XRT) has been the most commonly used form of RT. However, proton beam therapy (PBT) is gaining recogni
Externí odkaz:
https://doaj.org/article/9723583757f443f79537c57a412f592b
Autor:
Yun Hu, Sébastien Paris, Genevieve Bertolet, Hampartsoum B. Barsoumian, Kewen He, Duygu Sezen, Dawei Chen, Mark Wasley, Jordan DA SILVA, Joylise A. Mitchell, Tiffany A. Voss, Fatemeh Masrorpour, Claudia Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background While improvements in immunoradiotherapy have significantly improved outcomes for cancer patients, this treatment approach has nevertheless proven ineffective at controlling the majority of malignancies. One of the mechanisms of r
Externí odkaz:
https://doaj.org/article/a090d791bef0465c93bf5eb25e2451f7
Autor:
Andrew P. Jallouk, Sushanth Gouni, Jason Westin, Lei Feng, Haleigh Mistry, Raphael E. Steiner, Jinsu James, Mansoor Noorani, Sandra Horowitz, Nahum Puebla-Osorio, Luis E. Fayad, Swaminathan P. Iyer, Misha Hawkins, Christopher R. Flowers, Sairah Ahmed, Loretta J. Nastoupil, Partow Kebriaei, Elizabeth J. Shpall, Sattva S. Neelapu, Yago Nieto, Paolo Strati
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/e594de9ca2264723b1d6eb36952f069d
Autor:
Yun Hu, Sébastien Paris, Genevieve Bertolet, Hampartsoum B. Barsoumian, Qi Wang, Jordan Da Silva, Nalini B. Patel, Nguyen Nguyen, Denaha J. Doss, Ailing Huang, Ethan Hsu, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Carola Leuschner, Jordan T. Pietz, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The efficacy of immunoradiotherapy consisting of radiation therapy and immune checkpoint blockade relies on effectively promoting the systemic antitumor immune response’s activation while simultaneously reducing local factors favoring immune suppre
Externí odkaz:
https://doaj.org/article/b52124ce446c4e9989debf373cb9acaf
Autor:
Shonik Ganjoo, Nahum Puebla-Osorio, Selene Nanez, Ethan Hsu, Tiffany Voss, Hampartsoum Barsoumian, Lisa K. Duong, James W. Welsh, Maria Angelica Cortez
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The TGF-β superfamily is a group of secreted polypeptides with key roles in exerting and regulating a variety of physiologic effects, especially those related to cell signaling, growth, development, and differentiation. Although its central member,
Externí odkaz:
https://doaj.org/article/e91a14b21de541268f5347ee74c134da
Autor:
Duygu Sezen, Hampartsoum B. Barsoumian, Kewen He, Yun Hu, Qi Wang, Chike O. Abana, Nahum Puebla-Osorio, Ethan Y. Hsu, Mark Wasley, Fatemeh Masrorpour, Jing Wang, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Radiation therapy (XRT) has a well-established role in cancer treatment. Given the encouraging results on immunostimulatory effects, radiation has been increasingly used with immune-check-point inhibitors in metastatic disease, especially when immuno
Externí odkaz:
https://doaj.org/article/20ba2088e44043fcbe418952fcb64974
Autor:
Kewen He, Hampartsoum B. Barsoumian, Genevieve Bertolet, Vivek Verma, Carola Leuschner, Eugene J. Koay, Ethan B. Ludmir, Ethan Hsu, Esha Pisipati, Tiffany A. Voss, Nahum Puebla-Osorio, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite multiple therapeutic approaches, the presence of liver metastases carries a guarded prognosis, urgently necessitating further clinical and scientific research to develop curative interventions. The liver is an immunoprivileged organ that supp
Externí odkaz:
https://doaj.org/article/e149c14bb5724d3ea8bd7bd9998f2233