Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Nahla E. EL-Ashmawy"'
Publikováno v:
Clinical Phytoscience, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Background Acute myocardial infarction (AMI) is the most serious manifestation of coronary artery disease. The initial ischemia in AMI causes biochemical and metabolic alterations in cardiomyocytes. Objectives The present study aimed to inve
Externí odkaz:
https://doaj.org/article/1c8fff6594da46f3bab3cc1cfb2c8b42
Inhibition of PKC/MEK pathway suppresses β1-integrin and mitigates breast cancer cells proliferation
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1530-1537 (2021)
Prostaglandin E2 (PGE2) and β1-integrin have been correlated with breast cancer, where both could enhance progression and metastasis. Protein kinase C (PKC) and MEK have played a vital role in breast cancer development. Our study was conducted to el
Externí odkaz:
https://doaj.org/article/7c3256892a1d40958bd05a990190bbf0
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 23:3763-3770
The study aimed to investigate the anticancer effect of E-prostanoid receptor 1 (EP1) antagonist, SC19220, alone or in combination with the COX-2 inhibitor Celecoxob(CXB)® in mice bearing solid Ehrlich carcinoma (SEC).The tumors were induced in 40 f
Publikováno v:
Research Journal of Pharmacy and Technology. :3808-3813
Breast cancer is one of the most prevalence cancer that hits women around the world and the second cause of death among different cancer types. Breast cancer is heterogeneous and combines various subtypes and classes that makes the diagnosis and trea
Publikováno v:
Current Drug Safety. 17:250-258
Background: Anemia is one of the most common complications of Chronic Kidney Disease (CKD). The vast majority of Egyptian CKD patients are interchangeably treated with Darbepoetin Alfa (DPA) and Epoetin Alfa (EPA) to achieve and maintain target hemog
Publikováno v:
Biochemical and Biophysical Research Communications. 610:133-139
Liver x receptor α (LXRα) is a ligand-activated transcription factor belonging to the nuclear receptor superfamily. Oxysterols (endogenous oxidized cholesterol derivatives) are the most potent endogenous LXRα-agonist. LXRα has a direct impact on
Publikováno v:
International Immunopharmacology. 119:110148
Publikováno v:
Cell Biochemistry and Function. 39:350-356
Incidence and mortality rates of cancer continue to increase greatly despite the improved diagnostic and therapeutic methods. Based on GLOBOCAN estimates, the numbers of new cancer cases reported in 2018 were ~18.1 million, while the numbers of cance
Publikováno v:
Clinical and Experimental Medicine. 20:545-555
Gastrointestinal (GIT) cancers represent the third common cancers worldwide, characterized by rapid progression and higher mortality rate. Matrix metalloproteinases (MMPs) play an important role in cancer metastases. The present study was conducted t
Publikováno v:
Current drug safety.
Background: Lactoferrin (LF) is a member of the transferrin family, which is known for its immunomodulatory properties. LF has been widely used as an anticancer medication in various cancers including breast cancer. Aims: The current study aimed to e