Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Nahed El-Najjar"'
Autor:
Christina Pfab, Anush Abgaryan, Barbara Danzer, Fatme Mourtada, Weaam Ali, André Gessner, Nahed El-Najjar
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Drug-drug interaction (DDI), which can occur at the pharmacokinetics and/or the pharmacodynamics (PD) levels, can increase or decrease the therapeutic or adverse response of a drug itself or a combination of drugs. Cancer patients
Externí odkaz:
https://doaj.org/article/86c5e6b0e2a440068e3bb17de3ab33f3
Publikováno v:
Antibiotics, Vol 11, Iss 2, p 173 (2022)
The current antimicrobial therapy of bacterial infections of the central nervous system (CNS) in adults and pediatric patients is faced with many pitfalls as the drugs have to reach necessary levels in serum and cross the blood-brain barrier. Further
Externí odkaz:
https://doaj.org/article/47071ac4bddb4f9eaedaf4a9d553e08c
Publikováno v:
Antibiotics, Vol 9, Iss 6, p 309 (2020)
Flucloxacillin (FLU), an isoxazolyl penicillin, is widely used for the treatment of different bacterial infections in intensive care units (ICU). Being highly bound to plasma proteins, FLU is prone to drug-drug interactions (DDI) when administered co
Externí odkaz:
https://doaj.org/article/5084f6ceab7f476297a700b6041c8634
Autor:
David Busse, Wilhelm Huisinga, Charlotte Kloft, Christoph Dorn, Jens Markus Borghardt, Alice Pevzner, Hermann Wrigge, Philipp Simon, David Petroff, Nahed El-Najjar
Aims: The most suitable method for predicting the glomerular filtration rate (GFR) in obesity is currently debated. Therefore, multiple GFR/creatinine clearance prediction methods were applied to (morbidly) obese and nonobese patients ranging from mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b687e0c4b9022c4f0c8ccf3d03745b
https://refubium.fu-berlin.de/handle/fub188/33119
https://refubium.fu-berlin.de/handle/fub188/33119
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140683 (2015)
Recent developments in lipid mass spectrometry enable extensive lipid class and species analysis in metabolic disorders such as diabesity and metabolic syndrome. The minor plasma lipid class sphingosylphosphorylcholine (SPC) was identified as a ligan
Externí odkaz:
https://doaj.org/article/49949e78a0fd4f0b8fae743fd340259b
Autor:
Mirko Rossi, Christian Bolz, Joana Revez, Sundus Javed, Nahed El-Najjar, Florian Anderl, Heidi Hyytiäinen, Pia Vuorela, Markus Gerhard, Marja-Liisa Hänninen
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30543 (2012)
The confounding consequences of Helicobacter bilis infection in experimental mice populations are well recognized, but the role of this bacterium in human diseases is less known. Limited data are available on virulence determinants of this species. I
Externí odkaz:
https://doaj.org/article/d80dcfac6e154e20904c001c679e4a2f
Publikováno v:
Drug Testing and Analysis. 10:584-591
A large variation in the levels of different ß-lactams and other antibiotics used in critically ill patients has been documented. The aim of this study is to establish and validate a fast, ultra-performance liquid chromatography-tandem mass spectrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0471c64eae18ffb255f0fdbc816bfbc4
https://doi.org/10.1002/dta.2253
https://doi.org/10.1002/dta.2253
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 157
A simple and precise ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed for the simultaneous analysis of five anti-infective agents used to treat severe infections [three antibiotics (daptomycin, moxifl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0a513bec5424c172236c7fc4298869
https://pubmed.ncbi.nlm.nih.gov/29777985
https://pubmed.ncbi.nlm.nih.gov/29777985
Inflammation induced ER stress affects absorptive intestinal epithelial cells function and integrity
Publikováno v:
International immunopharmacology. 55
Recent studies have linked impairment of intestinal epithelial function in inflammatory bowel disease to the disturbance of endoplasmic reticulum homeostasis (ER) in response to stress. Most studies are on goblet and Paneth cells, which are considere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f0003ef4d4f33e3cbb933088956161
https://pubmed.ncbi.nlm.nih.gov/29324356
https://pubmed.ncbi.nlm.nih.gov/29324356
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
A simple and fast ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the analysis of Fosfomycin in different matrices (human plasma/urine, and aqueous fluid) has been established and validated. Sample cleanup con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daacf8b7c8cfb7970992c168f344f564
https://pubmed.ncbi.nlm.nih.gov/28709014
https://pubmed.ncbi.nlm.nih.gov/28709014