Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nahed El Kassar"'
Autor:
John F. McDyer, Mahzad Azimpouran, Valerie L. Durkalski-Mauldin, Robert G. Clevenger, Sharon D. Yeatts, Xutao Deng, William Barsan, Robert Silbergleit, Nahed El Kassar, Iulia Popescu, Dimiter Dimitrov, Wei Li, Emily J. Lyons, Sophia C. Lieber, Mars Stone, Frederick K. Korley, Clifton W. Callaway, Larry J. Dumont, Philip J. Norris, for the SIREN-C3PO Investigators
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
Multiple randomized, controlled clinical trials have yielded discordant results regarding the efficacy of convalescent plasma in outpatients, with some showing an approximately 2-fold reduction in risk and others showing no effect. We quantified bind
Externí odkaz:
https://doaj.org/article/7c19e4b03dd34452bc1b28ddfdf94cec
Autor:
Anton Ilich, Terry B. Gernsheimer, Darrell J. Triulzi, Heather Herren, Siobhan P. Brown, Lori A. Holle, Andrew T. Lucas, Bas de Laat, Nahed El Kassar, Alisa S. Wolberg, Susanne May, Nigel S. Key
Publikováno v:
Blood Advances. 7:900-908
The American Trial Using Tranexamic Acid (TXA) in Thrombocytopenia (A-TREAT, NCT02578901) demonstrated no superiority of TXA over placebo in preventing World Health Organization (WHO) grade 2 or higher bleeding in patients with severe thrombocytopeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3669d5a1a25c3b0a7c8fa22ef2096e9f
https://doi.org/10.1182/bloodadvances.2022008255
https://doi.org/10.1182/bloodadvances.2022008255
Autor:
Terry B. Gernsheimer, Siobhan P. Brown, Darrell J. Triulzi, Nigel S. Key, Nahed El Kassar, Heather Herren, Jacqueline N. Poston, Michael Boyiadzis, Brandi N. Reeves, Subodh Selukar, Monica B. Pagano, Scott Emerson, Susanne May
Publikováno v:
Blood. 140:1254-1262
Evidence of the effectiveness of prophylactic use of tranexamic acid (TXA) in thrombocytopenia is lacking. To determine whether TXA safely reduces bleeding incidence in patients undergoing treatment for hematologic malignancies, a randomized, double-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88ccd07cd2db1bc30ad944f7d6c73c1
https://doi.org/10.1182/blood.2022016308
https://doi.org/10.1182/blood.2022016308
Autor:
Joshua N. Goldstein, Andrew P. Cap, Alfonso Iorio, Nahed El Kassar, Roger J. Lewis, Andrei L. Kindzelski, Alan N. Barkun, Stephan A. Mayer, Philip C. Spinella, Jerrold H. Levy, Nigel S. Key, Dennis M. Jensen, Simon J. Stanworth, Marie E. Steiner, Terry Gernsheimer, Christopher S. Almond, John B. Holcomb, Ernest E. Moore
Publikováno v:
J Trauma Acute Care Surg
High-quality evidence guiding optimal transfusion and other supportive therapies to reduce bleeding is needed to improve outcomes for patients with either severe bleeding or hemostatic disorders that are associated with poor outcomes. Alongside chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6db23d97b77f98e697af97918ab67c0
https://doi.org/10.1097/ta.0000000000003300
https://doi.org/10.1097/ta.0000000000003300
Autor:
Robert F. Tamburro, Kenneth R. Cooke, Stella M. Davies, Samuel Goldfarb, James S. Hagood, Ashok Srinivasan, Marie E. Steiner, Dennis Stokes, Nancy DiFronzo, Nahed El-Kassar, Nonniekaye Shelburne, Aruna Natarajan, Neil Aggarwal, Michael Boeckh, Guang-Shing Cheng, Alpana Waghmare, Joshua Hill, Larissa Broglie, Jason Chien, Shane Cross, Jennifer McArthur, Christine N. Duncan, Leslie Lehmann, Christina Ullrich, Brian Fisher, Gerhard Hildebrandt, Robert R. Jenq, Kris M. Mahadeo, Sonata Jodele, James Kiley, Valerie Maholmes, Bethany Moore, Gregory Yanik, Lawrence Nogee, Sophie Paczesny, Courtney Rowan, Kirk R. Schultz, Kirsten Williams, Jason Woods, Matt S. Zinter
Publikováno v:
Ann Am Thorac Soc
Approximately 2,500 pediatric hematopoietic cell transplants (HCTs), most of which are allogeneic, are performed annually in the United States for life-threatening malignant and nonmalignant conditions. Although HCT is undertaken with curative intent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff1244b1a31e5a1f8b4e5bf86c0d6bd
https://doi.org/10.1513/annalsats.202001-006ot
https://doi.org/10.1513/annalsats.202001-006ot
Autor:
Sharon D. Yeatts, Robert Silbergleit, David G. Beiser, Jennifer M. Hah, Frederick K. Korley, Valerie Stevenson, William G. Barsan, Robertson D. Davenport, Christopher W. Jones, Ezekiel Lowell, Larry J. Dumont, Darrell J. Triulzi, Colin F. Greineder, Nahed El Kassar, Clifton W. Callaway, Joshua C. Reynolds, Aaron Burnett, Nathan L. Haas, Bory Kea, Kabir Yadav, Valerie Durkalski-Mauldin, Siddartha Jaiswal, Carol Van Huysen, John F. McDyer, Lydia D. Foster, Kevin A. Schulman, Alesia Kaplan, James V. Quinn
Publikováno v:
The New England Journal of Medicine
New England Journal of Medicine, vol 385, iss 21
New England Journal of Medicine, vol 385, iss 21
Background Early administration of convalescent plasma obtained from blood donors who have recovered from coronavirus disease 2019 (Covid-19) may prevent disease progression in acutely ill, high-risk patients with Covid-19. Methods In this randomized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da638931abc61aa040de19a6e2fb8b0
http://europepmc.org/articles/PMC8385553
http://europepmc.org/articles/PMC8385553
Autor:
Allan Doctor, Philip C. Spinella, Anne F. Eder, Pablo Cure, Stella T. Chou, Shimian Zou, Simon J. Stanworth, Myron A. Waclawiw, Marie E. Steiner, Naomi L.C. Luban, Martha Sola-Visner, Nahed El Kassar, Catherine Levy, William J. Savage, Jeanne E. Hendrickson, Alan E. Mast, Traci Heath Mondoro, Cassandra D. Josephson, Simone A. Glynn, Melania M. Bembea
Publikováno v:
Transfusion. 57:1568-1581
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d8c9f3f491e9b77287060e7268911ca
https://doi.org/10.1111/trf.14100
https://doi.org/10.1111/trf.14100
Autor:
Nahed El Kassar, Terry Gernsheimer, Darrell J. Triulzi, Susanne May, Siobhan P. Brown, Nigel S. Key, Heather Herren
Publikováno v:
Blood. 136:1-2
Background: Despite optimal prophylactic platelet (plt) transfusion therapy for severe thrombocytopenia in patients undergoing treatment for hematologic malignancy, WHO Grade 2 or greater bleeding continues to occur at rates of 43% to 70%. Although a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43d02b7d63811e3f34b202522193aa74
https://doi.org/10.1182/blood-2020-138920
https://doi.org/10.1182/blood-2020-138920
Autor:
Linda M. Griffith, Kirk R. Schultz, Stefanie Sarantopoulos, Robert Q. Le, Krishna V. Komanduri, Juan Gea-Banacloche, Paul A. Carpenter, John R. Wingard, Bipin N. Savani, Nahed El Kassar, Sophie Paczesny, Jo Anne H. Young
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 23(6)
Immune reconstitution after hematopoietic stem cell transplantation (HCT) beyond 1 year is not completely understood. Many transplant recipients who are free of graft-versus-host disease (GVHD) and not receiving any immunosuppression more than 1 year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7284ad9bd610ff007150b3c3c55dd6c4
https://pubmed.ncbi.nlm.nih.gov/27751936
https://pubmed.ncbi.nlm.nih.gov/27751936
Autor:
Ronald E. Gress, Francis A. Flomerfelt, Veena Kapoor, Lee A. Hugar, Philip J. Lucas, Kevin S. Chua, Nahed El-Kassar, Baishakhi Choudhury
Publikováno v:
International Immunology. 24:661-671
IL-7 signaling is required for thymocyte development and its loss has a severe deleterious effect on thymus function. Thymocyte–stromal cell interactions and other mechanisms tightly regulate IL-7 expression. We show that disruption of that regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3c60415c1976720b244f3cbb8ba0e9
https://doi.org/10.1093/intimm/dxs067
https://doi.org/10.1093/intimm/dxs067