Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nagwa Ben-Ghazzi"'
Autor:
Constanze Seidel, Sergio D. Moreno-Velásquez, Nagwa Ben-Ghazzi, Sara Gago, Nick D. Read, Paul Bowyer
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Aspergillus fumigatus is the most important mould pathogen in immunosuppressed patients. Suboptimal clearance of inhaled spores results in the colonisation of the lung airways by invasive hyphae. The first point of contact between A. fumigatus and th
Externí odkaz:
https://doaj.org/article/e41cfbb164564450800c51cb5374903c
Autor:
Sara Gago, Nicola L. D. Overton, Nagwa Ben-Ghazzi, Lilyann Novak-Frazer, Nick D. Read, David W. Denning, Paul Bowyer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Aspergillus fumigatus regularly colonises the lungs but in the context of respiratory disease can be associated with increased pathology. Here the authors show mutations in ZNF77 result in altered bronchial epithelial characteristics and enhanced fun
Externí odkaz:
https://doaj.org/article/61d2471016bd4353b85a81e3a4a5f756
Autor:
Nagwa Ben-Ghazzi, Sergio Moreno-Velásquez, Constanze Seidel, Darren Thomson, David W. Denning, Nick D. Read, Paul Bowyer, Sara Gago
Publikováno v:
Journal of Fungi, Vol 7, Iss 6, p 454 (2021)
The precise characterization of the mechanisms modulating Aspergillus fumigatus survival within airway epithelial cells has been impaired by the lack of live-cell imaging technologies and user-friendly quantification approaches. Here we described the
Externí odkaz:
https://doaj.org/article/e6d5ce42797b4c71b4b549f3ff8fa475
Publikováno v:
Annals of parasitology. 68(1)
Antifungal resistance represents a major clinical challenge to clinicians responsible for treating invasive fungal infections due to the limited arsenal of systemically available antifungal agents. Currently, fungal invasive infections are related to
Autor:
Sergio Moreno-Velásquez, Constanze Seidel, Paul Bowyer, Sara Gago, Nick D. Read, Nagwa Ben-Ghazzi, David W. Denning, Darren D. Thomson
Publikováno v:
Journal of Fungi
Volume 7
Issue 6
Journal of Fungi, Vol 7, Iss 454, p 454 (2021)
Ben Ghazzi, N, Moreno Velásquez, S, Seidel, C, Thomson, D, Denning, D W, Read, N, Bowyer, P & Gago, S 2021, ' Characterisation of Aspergillus fumigatus Endocytic Trafficking within Airway Epithelial Cells Using High-Resolution Automated Quantitative Confocal Microscopy ', Journal of Fungi . https://doi.org/10.3390/jof7060454
Volume 7
Issue 6
Journal of Fungi, Vol 7, Iss 454, p 454 (2021)
Ben Ghazzi, N, Moreno Velásquez, S, Seidel, C, Thomson, D, Denning, D W, Read, N, Bowyer, P & Gago, S 2021, ' Characterisation of Aspergillus fumigatus Endocytic Trafficking within Airway Epithelial Cells Using High-Resolution Automated Quantitative Confocal Microscopy ', Journal of Fungi . https://doi.org/10.3390/jof7060454
The precise characterization of the mechanisms modulating Aspergillus fumigatus survival within airway epithelial cells has been impaired by the lack of live-cell imaging technologies and user-friendly quantification approaches. Here we described the
Autor:
Paul Bowyer, Constanze Seidel, Sara Gago, Nick D. Read, Nagwa Ben-Ghazzi, Sergio D. Moreno-Velásquez
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Seidel, C, Moreno Velásquez, S S, Ben Ghazzi, N, Gago, S, Bowyer, P & Read, N 2020, ' Phagolysosomal survival enables non-lytic hyphal escape and ramification through lung epithelium during Aspergillus fumigatus infection ', Frontiers in Microbiology, vol. 11, 1955, pp. 1-13 . https://doi.org/10.3389/fmicb.2020.01955
Seidel, C, Moreno Velásquez, S S, Ben Ghazzi, N, Gago, S, Bowyer, P & Read, N 2020, ' Phagolysosomal survival enables non-lytic hyphal escape and ramification through lung epithelium during Aspergillus fumigatus infection ', Frontiers in Microbiology, vol. 11, 1955, pp. 1-13 . https://doi.org/10.3389/fmicb.2020.01955
Aspergillus fumigatus is the most important mould pathogen in immunosuppressed patients. Suboptimal clearance of inhaled spores results in the colonisation of the lung airways by invasive hyphae. The first point of contact between A. fumigatus and th
Autor:
Andrea Trabocchi, Silvia Carbonell, Antonio Guarna, Duccio Cavalieri, Irene Stefanini, Marta Gut, Paul Bowyer, Damariz Rivero, Ivo Gut, Misha Kapushesky, Nagwa Ben Ghazzi, Lisa Rizzetto, Simon Heath
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Stefanini, I, Rizzetto, L, Rivero, D, Carbonell, S, Gut, M, Heath, S, Gut, I G, Trabocchi, A, Guarna, A, Ben Ghazzi, N, Bowyer, P, Kapushesky, M & Cavalieri, D 2018, ' Deciphering the mechanism of action of 089, a compound impairing the fungal cell cycle ', Scientific Reports, vol. 8, no. 1, 5964 . https://doi.org/10.1038/s41598-018-24341-y
Recercat. Dipósit de la Recerca de Catalunya
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Scientific Reports
Stefanini, I, Rizzetto, L, Rivero, D, Carbonell, S, Gut, M, Heath, S, Gut, I G, Trabocchi, A, Guarna, A, Ben Ghazzi, N, Bowyer, P, Kapushesky, M & Cavalieri, D 2018, ' Deciphering the mechanism of action of 089, a compound impairing the fungal cell cycle ', Scientific Reports, vol. 8, no. 1, 5964 . https://doi.org/10.1038/s41598-018-24341-y
Recercat. Dipósit de la Recerca de Catalunya
instname
Fungal infections represent an increasingly relevant clinical problem, primarily because of the increased survival of severely immune-compromised patients. Despite the availability of active and selective drugs and of well-established prophylaxis, cl
Autor:
Nagwa Ben-Ghazzi, David W. Denning, Nick D. Read, Paul Bowyer, Nicola L. D. Overton, Sara Gago, Lilyann Novak-Frazer
Publikováno v:
Gago, S, Overton, N, Ben Ghazzi, N, Novak Frazer, L, Read, N, Denning, D W & Bowyer, P 2018, ' Lung colonization by Aspergillus fumigatus is controlled by ZNF77 ', Nature Communications, vol. 9, 3835 . https://doi.org/10.1038/s41467-018-06148-7
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Aspergillus fumigatus is a critical pathogen of humans. Exposure to A. fumigatus conidia occurs frequently but is normally cleared from the respiratory airways. In contrast, individuals with respiratory diseases are often highly colonized by fungi. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6148779268178ef2bebafe7d887b4d2
https://doi.org/10.1038/s41467-018-06148-7
https://doi.org/10.1038/s41467-018-06148-7