Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Naguib Muhsen"'
Autor:
Caroline Derne, GangaRaju Golla, Eric Legangneux, Shibadas Biswal, Uday Kiran Veldandi, Naguib Muhsen
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 52:996-1004
OBJECTIVE To evaluate the effects of siponimod (BAF312) on the pharmacokinetics (PK) and pharmacodynamics (PD) of a monophasic oral contraceptive (OC). MATERIALS AND METHODS This was a phase 1, single-center, open-label, multipledose, single-sequence
Publikováno v:
International journal of clinical pharmacology and therapeutics. 53(9)
Objective Selexipag is a novel, oral, selective prostacyclin (PGI2) receptor agonist in clinical development for the treatment of pulmonary arterial hypertension. Film-coated tablets with strength between 200 and 1,600 μg were used. Bioequivalence b