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pro vyhledávání: '"Nagraj K. Bokinkere"'
Autor:
Stephen M. Roberts, John W. Munson, Nigel G. J. Richards, Nagraj K. Bokinkere, Jennifer L. Brown, Florence M. Ndikum-Moffor
Publikováno v:
Chemical Research in Toxicology. 11:185-192
Cocaine is capable of producing hepatic necrosis in laboratory animals and humans. Studies in mice indicate that N-oxidative metabolism of cocaine is required for hepatotoxicity and have suggested that toxicity may result from the adduction of protei