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pro vyhledávání: '"Nagothy Preethy"'
Autor:
Sourav Pal, Vinay Kumar, Biswajit Kundu, Debomita Bhattacharya, Nagothy Preethy, Mamindla Prashanth Reddy, Arindam Talukdar
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 291-310 (2019)
Camptothecin (CPT), a natural product and its synthetic derivatives exert potent anticancer activity by selectively targeting DNA Topoisomerase I (Top1) enzyme. CPT and its clinically approved derivatives are used as Top1 poisons for cancer therapy s
Externí odkaz:
https://doaj.org/article/0515aabdf6dc43bdbd8b6a93b16597cd
Autor:
Vinay Kumar, Biswajit Kundu, Arindam Talukdar, Mamindla Prashanth Reddy, Nagothy Preethy, Debomita Bhattacharya, Sourav Pal
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 291-310 (2019)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Camptothecin (CPT), a natural product and its synthetic derivatives exert potent anticancer activity by selectively targeting DNA Topoisomerase I (Top1) enzyme. CPT and its clinically approved derivatives are used as Top1 poisons for cancer therapy s
Autor:
Sunny Goon, Barnali Paul, Dipyaman Ganguly, Oindrila Rahaman, Nagothy Preethy, Dipika Sarkar, Arindam Talukdar, Swarnali Roy, Sourav Pal, Purbita Bandopadhyay
Publikováno v:
European Journal of Medicinal Chemistry. 210:112978
Aberrant activation of the endosomal Toll-like receptor 7 (TLR7) has been implicated in myriad autoimmune diseases and is an established therapeutic target in such conditions. Development of diverse TLR7 antagonists is mainly accomplished through ran