Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Naglaa Mohamed Ahmed"'
Autor:
Sahar A. Ali, Samir Mohamed Awad, Ahmed Mohammed Said, Shahenda Mahgoub, Heba Taha, Naglaa Mohamed Ahmed
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 847-863 (2020)
Oxidative stress is one of the main causes of significant severe diseases. The discovery of new potent antioxidants with high efficiency and low toxicity is a great demand in the field of medicinal chemistry. Herein, we report the design, synthesis m
Externí odkaz:
https://doaj.org/article/77ea4f1e407d4572a3f773abe54807fd
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1110-1120 (2019)
New anticancer agents are highly needed to overcome cancer cell resistance. A novel series of pyrimidine pyrazoline-anthracene derivatives (PPADs) (4a-t) were designed and synthesised. The anti-liver cancer activity of all compounds was screened in v
Externí odkaz:
https://doaj.org/article/ffe162c5d3204b3d9093d96c576d0394
Publikováno v:
World Journal of Advanced Research and Reviews. 15:272-296
Pyrimidines represent an important class of heterocycles containing two nitrogen atoms at position 1 and 3 of the six membered ring show wide range of biological activities. Numerous methods for the synthesis of pyrimidine and their diverse reactions
Publikováno v:
Journal of Pharmaceutical Research International. :49-67
Aim: As part of ongoing studies in developing new anti-inflammatory agents, 2-thioxo-1,2,3,4-tetrahydropyrimidine derivative 1 was synthesized by direct Biginelli condensation and used for the synthesis of novel series of pyrimidin-2-thione derivativ
Autor:
Ahmed M. Said, Naglaa Mohamed Ahmed, Shahenda Mahgoub, Sahar A. Ali, Samir M. Awad, Heba Taha
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 847-863 (2020)
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 847-863 (2020)
Oxidative stress is one of the main causes of significant severe diseases. The discovery of new potent antioxidants with high efficiency and low toxicity is a great demand in the field of medicinal chemistry. Herein, we report the design, synthesis m
Publikováno v:
Molecules
Volume 26
Issue 7
Molecules, Vol 26, Iss 1838, p 1838 (2021)
Volume 26
Issue 7
Molecules, Vol 26, Iss 1838, p 1838 (2021)
Scaffolds hybridization is a well-known drug design strategy for antitumor agents. Herein, series of novel indolyl-pyrimidine hybrids were synthesized and evaluated in vitro and in vivo for their antitumor activity. The in vitro antiproliferative act
Autor:
Mosad Sayed, Naglaa Mohamed Ahmed
Publikováno v:
Journal of Advanced Pharmacy Research. 1:75-88
A literature survey revealed that the thiouracil derivatives and their condensed heterocycles have occupied a marked position as synthon for various biologically active compounds. They have a wide range of therapeutic uses that include anti-cancer, a
Publikováno v:
Alexandria Science Exchange Journal. 35:486-515
Publikováno v:
European Journal of Medicinal Chemistry. 69:591-600
A series of 6-aryl-5-cyano thiouracil derivatives ( 2a-c to 11a-c ) was synthesized from 6-aryl-4-hydrazino-2-thioxo-1,2-dihydropyrimidine-5-carbonitriles ( 1a-c ). The products were characterized by analytical and spectral data (IR, 1 H NMR, 13 C NM
Publikováno v:
Acta pharmaceutica (Zagreb, Croatia). 61(2)
Synthesis and antimicrobial evaluation of some 6-aryl-5-cyano-2-thiouracil derivativesA series of 6-aryl-5-cyano-2-thiouracil derivatives (1a-d) was synthesized by the reaction of ethyl cyanoacetate with thiourea and aldehydes. These products were us