Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nagisa Yoshida"'
Autor:
Jake R. Thomas, Anna Appios, Emily F. Calderbank, Nagisa Yoshida, Xiaohui Zhao, Russell S. Hamilton, Ashley Moffett, Andrew Sharkey, Elisa Laurenti, Courtney W. Hanna, Naomi McGovern
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The generation of primitive macrophages remains a poorly understood process in humans. Here, the authors identify placental erythro-myeloid progenitors that give rise to foetal macrophages in the early human placenta and demonstrate that epigenetic s
Externí odkaz:
https://doaj.org/article/370741294d1d45e496cf44e8daffe8d6
Autor:
Artur Yakimovich, Moona Huttunen, Jerzy Samolej, Barbara Clough, Nagisa Yoshida, Serge Mostowy, Eva-Maria Frickel, Jason Mercer
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT The use of deep neural networks (DNNs) for analysis of complex biomedical images shows great promise but is hampered by a lack of large verified data sets for rapid network evolution. Here, we present a novel strategy, termed “mimicry embe
Externí odkaz:
https://doaj.org/article/d26b0508dfde4b1581e6233c5ef9daa5
Autor:
Nagisa Yoshida, Marie-Charlotte Domart, Christopher J. Peddie, Artur Yakimovich, Maria J. Mazon-Moya, Thomas A. Hawkins, Lucy Collinson, Jason Mercer, Eva-Maria Frickel, Serge Mostowy
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Toxoplasma gondii is an obligate intracellular parasite capable of invading any nucleated cell. Three main clonal lineages (type I, II, III) exist and murine models have driven the understanding of general and strain-specific immune mechanisms underl
Externí odkaz:
https://doaj.org/article/1f30f192458a48f0b9a4a5258854e6b5
Autor:
Anna Sanecka, Nagisa Yoshida, Elizabeth Motunrayo Kolawole, Harshil Patel, Brian D. Evavold, Eva-Maria Frickel
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T cell receptor–major histocompatibility complex (TCR–MHC) affinities span a wide range in a polyclonal T cell response, yet it is undefined how affinity shapes long-term properties of CD8 T cells during chronic infection with persistent antigen.
Externí odkaz:
https://doaj.org/article/df6b750c72a44d789dfeb87e59c65db2
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Macrophages provide front line defense against infections. The study of macrophage–microbe interplay is thus crucial for understanding pathogenesis and infection control. Zebrafish (Danio rerio) larvae provide a unique platform to study macrophage
Externí odkaz:
https://doaj.org/article/0b221a206d57488db8f538832d2df944
Autor:
Lee Kim Swee, Zhen Wei Tan, Anna Sanecka, Nagisa Yoshida, Harshil Patel, Gijsbert Grotenbreg, Eva-Maria Frickel, Hidde L. Ploegh
Publikováno v:
Open Biology, Vol 6, Iss 11 (2016)
T-cell identity is established by the expression of a clonotypic T-cell receptor (TCR), generated by somatic rearrangement of TCRα and β genes. The properties of the TCR determine both the degree of self-reactivity and the repertoire of antigens th
Externí odkaz:
https://doaj.org/article/66b62db06e24433da7a409fcf108233e
Autor:
Sophie Curio, Sarah C Edwards, Toshiyasu Suzuki, Jenny McGovern, Chiara Triulzi, Nagisa Yoshida, Gustav Jonsson, Teresa Glauner, Damiano Rami, Robert Wiesheu, Anna Kilbey, Rachel Violet Purcell, Seth B Coffelt, Nadia Guerra
Publikováno v:
Discovery immunology. 1(1)
γδT cells are unconventional T cells particularly abundant in mucosal tissues that play an important role in tissue surveillance, homeostasis, and cancer. γδT cells recognize stressed cells or cancer cells through the NKG2D receptor to kill these
Autor:
Chie Umatani, Nagisa Yoshida, Eri Yamamoto, Yasuhisa Akazome, Yasutaka Mori, Shinji Kanda, Kataaki Okubo, Yoshitaka Oka
Publikováno v:
Endocrinology. 163
Animals properly perform sexual behaviors by using multiple sensory cues. However, neural mechanisms integrating multiple sensory cues and regulating motivation for sexual behaviors remain unclear. Here, we focused on peptidergic neurons, terminal ne
Autor:
Jenny McGovern, Damiano Rami, Rachel V. Purcell, Sarah C. Edwards, Gustav Jonsson, Chiara Triulzi, Sophie Curio, Teresa Glauner, Nadia Guerra, Toshiyasu Suzuki, Seth B. Coffelt, Nagisa Yoshida
{gamma}{delta}T cells are unconventional T cells particularly abundant in mucosal tissues that play an important role in tissue surveillance and homeostasis. {gamma}{delta}T cell activation is mediated by the T cell receptor composed of {gamma} and {
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8770a8a10c42a6752954f4aed4b671d6
https://doi.org/10.1101/2021.08.26.457761
https://doi.org/10.1101/2021.08.26.457761
Autor:
Serge Mostowy, Marie-Charlotte Domart, Eva-Maria Frickel, Nagisa Yoshida, Lucy M. Collinson, Maria J. Mazon-Moya, Jason Mercer, Christopher J. Peddie, Thomas A. Hawkins, Artur Yakimovich
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Disease Models & Mechanisms
Disease Models & Mechanisms
Toxoplasma gondii is an obligate intracellular parasite capable of invading any nucleated cell. Three main clonal lineages (type I, II, III) exist and murine models have driven the understanding of general and strain-specific immune mechanisms underl