Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nagisa Hasegawa"'
Autor:
Changshan Wang, Motohiko Oshima, Goro Sashida, Takahisa Tomioka, Nagisa Hasegawa, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Yoichiro Kusunoki, Seishi Kyoizumi, Kazue Imai, Kei Nakachi, Atsushi Iwama
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132041 (2015)
Precise understanding of radiation effects is critical to develop new modalities for the prevention and treatment of radiation-induced damage. We previously reported that non-lethal doses of X-ray irradiation induce DNA damage in human hematopoietic
Externí odkaz:
https://doaj.org/article/e4c7b57f27af4e25b1c48c88079e5b37
Autor:
Atsushi Iwama, Chiaki Nakaseko, Yusuke Takeda, Masahiro Takeuchi, Koutaro Yokote, Emi Togasaki, Emiko Sakaida, Shuhei Koide, Tomoya Muto, Shokichi Tsukamoto, Tohru Iseki, Yusuke Isshiki, Naoya Mimura, Shio Sakai, Kwangmin Choi, Chikako Ohwada, Daniel T. Starczynowski, Nagisa Hasegawa, Chika Kawajiri-Manako, Kazumasa Aoyama, Yuhei Nagao, Ryo Shimizu
Publikováno v:
Leukemia Research. 50:85-94
Expression of the tumor suppressor gene NR4A3 is silenced in the blasts of acute myeloid leukemia (AML), irrespective of the karyotype. Although the transcriptional reactivation of NR4A3 is considered to have a broad-spectrum anti-leukemic effect, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88638ffafd95b623bd0f24262bee693c
https://doi.org/10.1016/j.leukres.2016.09.018
https://doi.org/10.1016/j.leukres.2016.09.018
Autor:
Kozaburo Ohashi, Katsuhito Nagai, Michiaki Myotoku, Miki Yamashiro, Nagisa Hasegawa, Satoshi Nishii, Yasutoshi Hatsuda, Masafumi Ogawa, Sachiko Omotani
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 42:31-39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb44dffe0ab22c3fdce697a7983b1506
https://doi.org/10.5649/jjphcs.42.31
https://doi.org/10.5649/jjphcs.42.31
Autor:
Chiaki Nakaseko, Koutaro Yokote, Atsushi Iwama, Goro Sashida, Tomoya Muto, Kazuya Shimoda, Nagisa Hasegawa
Publikováno v:
Leukemia & Lymphoma. 56:520-523
TET2 mutations have been frequently observed in myeloid malignancies including acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), myeloproliferative neoplasm (MPN) and MDS/MPN [1–4]. TET...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b5c8ced5591dfe212eb166c0c644b3
https://doi.org/10.3109/10428194.2014.924120
https://doi.org/10.3109/10428194.2014.924120
Autor:
Masahiro Takeuchi, Tohru Iseki, Shio Sakai, Chiaki Nakaseko, Emi Togasaki, Chikako Ohwada, Atsuko Yamazaki, Emiko Sakaida, Yusuke Takeda, Takeharu Kawaguchi, Ryoh Shimizu, Naomi Shimizu, Satoshi Ota, Koutaro Yokote, Nagisa Hasegawa, Yasumasa Sugita, Yusuke Isshiki, Shokichi Tsukamoto
Publikováno v:
Internal Medicine. 53:1159-1164
Myeloid sarcoma (MS) is an extramedullary myeloid tumor that sometimes presents with antedating systemic leukemia, leading physicians to the misdiagnosis of lymphoma. CD25 is expressed in 13% of patients with acute myeloid leukemia (AML), and its exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71138dffff699eee48f44f9a71f6024f
https://doi.org/10.2169/internalmedicine.53.1137
https://doi.org/10.2169/internalmedicine.53.1137
Autor:
Kenji, Kimura, Masahiro, Takeuchi, Nagisa, Hasegawa, Emi, Togasaki, Ryoh, Shimizu, Chika, Kawajiri, Tomoya, Muto, Shokichi, Tsukamoto, Yusuke, Takeda, Chikako, Ohwada, Emiko, Sakaida, Shio, Sakai, Naoya, Mimura, Satoshi, Ota, Tohru, Iseki, Chiaki, Nakaseko
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 57(6)
A 34-year-old man who had been referred to our hospital was diagnosed with acute promyelocytic leukemia (APL). All-trans retinoic acid (ATRA), oral administration, was initiated. On day 25, he developed fever and respiratory distress with bilateral p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b30ae797bc5af3dc969f4c7f665b8ffd
https://pubmed.ncbi.nlm.nih.gov/27384858
https://pubmed.ncbi.nlm.nih.gov/27384858
Autor:
Atsushi Iwama, Chiaki Nakaseko, Tomoya Muto, Motohiko Oshima, Kazuya Shimoda, Changshan Wang, Kotaro Yokote, Shuhei Koide, Atsunori Saraya, Nagisa Hasegawa, Kiyoko Takane, Atsushi Kaneda, Goro Sashida, Hirotaka Matsui
Publikováno v:
Leukemia. 31(4)
Somatic inactivating mutations in epigenetic regulators are frequently found in combination in myelodysplastic syndrome (MDS). However, the mechanisms by which combinatory mutations in epigenetic regulators promote the development of MDS remain unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddcb0cbbdef68b05f8f755a319a0a5b
https://pubmed.ncbi.nlm.nih.gov/27694924
https://pubmed.ncbi.nlm.nih.gov/27694924
Autor:
Changshan Wang, Atsunori Saraya, Atsushi Iwama, George R. Wendt, Tomoya Muto, Shuhei Koide, Yutaka Suzuki, Motohiko Oshima, Satoru Miyagi, Makiko Mochizuki-Kashio, Nagisa Hasegawa, Kazuya Shimoda, Shogo Yabata
Publikováno v:
Experimental hematology. 44(4)
Fetal liver hematopoietic stem cells (HSCs) seed bone marrow (BM) and undergo reprograming into adult-type HSCs that are largely quiescent and restricted in their self-renewal activity. Here we report that in the absence of the polycomb-group gene Ez
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed00f8d35052ff2cc88c8306cc6701f
https://pubmed.ncbi.nlm.nih.gov/26773568
https://pubmed.ncbi.nlm.nih.gov/26773568
Publikováno v:
ENVIRONMENTAL SYSTEMS RESEARCH. 33:469-475
手入れの行き届かない人工林は, 健全性を失い, 本来もつ多様な機能を十分に発揮できない現況にあり, 適切かつ持続可能な人工林の維持管理が必要不可欠となっている. 本研究では, 広範
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9f471dee5f240d8675edceceb935f9
https://doi.org/10.2208/proer.33.469
https://doi.org/10.2208/proer.33.469
Autor:
Naoya Mimura, Atsushi Iwama, Chika Kawajiri, Emiko Sakaida, Chiaki Nakaseko, Nagisa Hasegawa, Chikako Ohwada, Yusuke Takeda, Ryo Shimizu, Tohru Iseki, Yuhei Nagao, Emi Togasaki, Shuhei Koide, Shio Sakai, Koutaro Yokote, Masahiro Takeuchi, Tomoya Muto
Publikováno v:
Blood. 126:3640-3640
The expression of NR4A3, which is a member of the gene encoding NR4A orphan nuclear receptor subfamily, has been reported to be commonly silenced in blasts of patients with acute myeloid leukemia (AML), irrespective of karyotype. In line with this fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ed0e6da113caef15001cbdc71e1499f
https://doi.org/10.1182/blood.v126.23.3640.3640
https://doi.org/10.1182/blood.v126.23.3640.3640