Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nagina Mangal"'
Publikováno v:
Journal of Cannabis Research, Vol 6, Iss 1, Pp 1-13 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies with a median 5 year-survival rate of 12%. Cannabidiol (CBD) has been found to exhibit antineoplastic potential and may potentiate the anticancer effects
Externí odkaz:
https://doaj.org/article/7b04a5dfcf7b4f6281e4fe12dfe7ded1
Autor:
Patrick V. Lawrence, Krisha Desai, Christopher Wadsworth, Nagina Mangal, Hemant M. Kocher, Nagy Habib, Anguraj Sadanandam, Mikael H. Sodergren
Publikováno v:
Current Oncology, Vol 29, Iss 10, Pp 6754-6763 (2022)
Background: Most patients with pancreatic ductal adenocarcinoma (PDAC) are metastatic at presentation with dismal prognosis warranting improved systemic therapy options. Longitudinal sampling for the assessment of treatment response poses a challenge
Externí odkaz:
https://doaj.org/article/d123e1a762b94871b2cc312440ff6c7f
Autor:
Mikael H. Sodergren, Oliver Salazar, Rishi Banerjee, Daniel Couch, Simon Erridge, Barbara Pacchetti, Nagina Mangal
Publikováno v:
Therapeutic Innovation & Regulatory Science
Background Whilst access to cannabis-based medicinal products (CBMPs) has increased globally subject to relaxation of scheduling laws globally, one of the main barriers to appropriate patient access remains a paucity of high-quality evidence surround
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c444881df4a71d878fd1486f86d1219
http://europepmc.org/articles/PMC8688379
http://europepmc.org/articles/PMC8688379
Autor:
Nagina Mangal, Nagy A. Habib, Mikael H. Sodergren, Anguraj Sadanandam, Simon Erridge, Vikash Reebye
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal studies in support of cannabinoids possessing anticancer properties. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1735bf062e20b9686694b5c23f44e8c7
http://europepmc.org/articles/PMC8310855
http://europepmc.org/articles/PMC8310855
Autor:
Harpreet Wasan, Long R. Jiao, Anguraj Sadanandam, Mikael H. Sodergren, V. P. Balachandran, Nagy A. Habib, Nagina Mangal
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Advances in surgery, peri-operative care and systemic chemotherapy have not significantly improved the prognosis of pancreatic cancer for several decades. Early clinical trials of immunotherapy have yielded disappointing results proposing other means
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507bfdf2b4fbe3bb7f9b42bf4cd787bf
https://doi.org/10.1007/s00432-020-03332-5
https://doi.org/10.1007/s00432-020-03332-5
Publikováno v:
Cannabis Cannabinoid Res
Background: Cachexia is a prevalent condition associated with underlying chronic disease. Wasting of skeletal muscle and adipose tissue loss in cachectic patients is associated with higher rates of disability, reduced quality of life (QoL), and worse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d2f5f0d60807b23c5a1c8a12577fff
https://europepmc.org/articles/PMC8713261/
https://europepmc.org/articles/PMC8713261/
Autor:
Anguraj Sadanandam, Christopher A. Wadsworth, Mikael H. Sodergren, Krisha Desai, Nagina Mangal, Nagy A. Habib, Patrick Varun Lawrence
BackgroundMost patients with pancreatic ductal adenocarcinoma (PDAC) are metastatic at presentation with dismal prognosis warranting improved systemic therapy options. Longitudinal sampling for assessment of treatment response poses a challenge for v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7379c479150aba9289d69dbe0233bcc5
https://doi.org/10.21203/rs.3.rs-668215/v1
https://doi.org/10.21203/rs.3.rs-668215/v1
Autor:
Enas Abu-Shah, Nagina Mangal, Zahir Soonawalla, Lara R. Heij, Rachael Bashford-Rogers, Elke Kurz, Srikanth Reddy, Michael Silva, Alistair Easton, Ashwin Kumar Jainarayanan, Mark R. Middleton, Edward H Arbe-Barnes, Aniko Rendek, David Ahern, Michael L. Dustin, Shivan Sivakumar
Publikováno v:
Cancers, Vol 13, Iss 1776, p 1776 (2021)
Cancers
Volume 13
Issue 8
Cancers
Volume 13
Issue 8
Simple Summary Pancreatic cancer has the worst survival of any human cancer. Checkpoint blockade has not yielded much benefit in pancreatic cancer. We explored immune cell phenotypes with this disease to identify new targets for checkpoint blockade t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603bb41840d2114c2bbad47741fcf224
https://www.mdpi.com/2072-6694/13/8/1776
https://www.mdpi.com/2072-6694/13/8/1776
Autor:
Michael L. Dustin, Elke Kurz, Zahir Soonawalla, Srikanth Reddy, Mark R. Middleton, Alistair Easton, Enas Abu-Shah, Edward H Arbe-Barnes, David Ahern, Aniko Rendek, Michael Silva, Rachael Bashford Rogers, Shivan Sivakumar, Nagina Mangal, Lara R. Heij
Pancreatic cancer has the worst prognosis of any human malignancy and leukocyte infiltration is a major prognostic marker of the disease. As current immunotherapies confer negligible survival benefits, there is a need to better characterise leukocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7009903e8147a42abcc0925921579274
https://doi.org/10.1101/2020.06.20.163071
https://doi.org/10.1101/2020.06.20.163071
Autor:
Enas Abu-Shah, Michael L. Dustin, Shivan Sivakumar, Michael Silva, Nagina Mangal, Zahir Soonawalla, Srikanth Reddy, Aniko Rendek, David Ahern, Mark R. Middleton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b56e7b0b7d8ce76cdbbbe298217cea
https://ora.ox.ac.uk/objects/uuid:28dd6b82-c797-4dbf-85c1-d653f15a7832
https://ora.ox.ac.uk/objects/uuid:28dd6b82-c797-4dbf-85c1-d653f15a7832