Discovery and structure activity relationships of 2-pyrazolines derived from chalcones from a pest management perspective

Autor: Abbas Ali, David E. Wedge, Ikhlas A. Khan, Nurhayat Tabanca, Nagihan Beyhan, Ulrich R. Bernier, Bedia Koçyiğit-Kaymakçıoğlu, Stephen O. Duke

Publikováno v: Medicinal Chemistry Research. 24:3632-3644

Synthesis of chalcones and 2-pyrazoline derivatives has been an active field of research due to the established pharmacological effects of these compounds. In this study, a series of chalcone (1a–i), 2-pyrazoline-1-carbothioamides (2a–i), and 2-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fc44ff1c22e5cbf6a527c0f9aaa53d6
https://doi.org/10.1007/s00044-015-1415-8

Şalkonlardan Türetilen Bazı 2 -Pirazolinlerin Sentezi ve Antikonvulsan Aktiviteleri

Autor: Salih GÜMRU, Hale Z. TOKLU, Nagihan BEYHAN, Elçin E. ORUÇ EMRE, Bedia KOÇYİĞİT KAYMAKÇIOĞLU, Feyza ARICIOĞLU

Publikováno v: Volume: 1, Issue: 2 137-8
Anadolu University Journal of Science and Technology C-Life Sciences and Biotechnology
Anadolu University Journal of Science and Technology-C. Life Sciences and Biotechnology, Vol 1, Iss 2, Pp 137-144 (2011)

In the present study, a series of chalcones were prepared by Claisen Schmidt condensation as starting compounds and 2-pyrazoline derivatives have been synthesized by the reaction of chalcones with thiosemicarbazide. Their structures have been confirm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5ab09598d01b699f00a761b901f370f2
https://hdl.handle.net/11421/1528

Antidepressant-like Activity of 2-Pyrazoline Derivatives

Autor: Salih Gümrü, Feyza Aricioglu, Bedia Koçyiğit Kaymakçıoğlu, Nagihan Beyhan

Publikováno v: Volume: 3, Issue: 3 154-158
Clinical and Experimental Health Sciences

Objective: Depression is a common chronic recurrent psychiatric disorder, characterised by clusters of symptoms affecting many different systems. Due to complexity of the pathogenesis and differences in response to treatment, current therapies are in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7927f925556f5a8bd8fdf588c03c92
https://doi.org/10.5455/musbed.20130916091055

Antiproliferative activity of some tautomeric hydrazones derived from chalcones.

Autor: TOK, Fatih¹, BEYHAN, Nagihan¹, ERZURUMLU, Yalçın², İLHAN, Recep², BALLAR, Petek², KOCYIGIT-KAYMAKCIOGLU, Bedia¹ bkaymakcioglu@marmara.edu.tr

Publikováno v: Marmara Pharmaceutical Journal. 2016, Vol. 20 Issue 2, p157-163. 7p.