The effects of antimicrobials and lipopolysaccharide on acute immune responsivity in pubertal male and female CD1 mice

Autor: Pasquale Esposito, Madeleine M. Kearns, Kevin B. Smith, Rajini Chandrasegaram, Anthony K. Kadamani, Michelle Gandelman, Jacky Liang, Naghmeh Nikpoor, Thomas A. Tompkins, Nafissa Ismail

Publikováno v: Comprehensive Psychoneuroendocrinology, Vol 11, Iss , Pp 100147- (2022)

Exposure to stress during critical periods of development—such as puberty—is associated with long-term disruptions in brain function and neuro-immune responsivity. However, the mechanisms underlying the effect of stress on the pubertal neuro-immu

Externí odkaz: https://doaj.org/article/145d7540bf924338bce97d59f15f689d

In Vitro Probiotic Modulation of the Intestinal Microbiota and 2′Fucosyllactose Consumption in Fecal Cultures from Infants at Two Months of Age

Autor: Alicja M. Nogacka, Silvia Arboleya, Naghmeh Nikpoor, Jeremie Auger, Nuria Salazar, Isabel Cuesta, Jorge R. Alvarez-Buylla, Laura Mantecón, Gonzalo Solís, Miguel Gueimonde, Thomas A. Tompkins, Clara G. de los Reyes-Gavilán

Publikováno v: Microorganisms, Vol 10, Iss 2, p 318 (2022)

2′-fucosyllactose (2′FL) is one of the most abundant oligosaccharides in human milk, with benefits on neonatal health. Previous results point to the inability of the fecal microbiota from some infants to ferment 2′FL. We evaluated a probiotic f

Externí odkaz: https://doaj.org/article/ae557c24385b46d688f5314c8d456c41

Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy

Autor: Chunlong Mu, Naghmeh Nikpoor, Thomas A. Tompkins, Jong M. Rho, Morris H. Scantlebury, Jane Shearer

Publikováno v: EBioMedicine. 76

Infantile spasms syndrome (IS) is a type of epilepsy affecting 1.6 to 4.5 per 10,000 children in the first year of life, often with severe lifelong neurodevelopmental consequences. Only two first-line pharmacological treatments currently exist for IS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937cd5845f8fef008473eec1125702c7
https://pubmed.ncbi.nlm.nih.gov/35148983

Complete Genome Sequence of Phascolarctobacterium faecium G 104, Isolated from the Stools of a Healthy Lean Donor

Autor: Aitor Gonzaga, Naghmeh Nikpoor, Yolanda Sanz, Thomas A. Tompkins, Sadjia Rachek, Eva M. Gómez del Pulgar

Publikováno v: Digital.CSIC: Repositorio Institucional del CSIC
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Phascolarctobacterium faecium is a strict anaerobe belonging to the Firmicutes phylum that is found abundantly in the human gastrointestinal tract. Here, we report the complete genome sequence of P. faecium G 104, a strain isolated from a fresh stool

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0375f91259a5a012f4732e367533a533

Abstract 48: A newly identified rare variant (chr11:47227430) with possible functional activity is associated with fasting insulin at the chromosome 11p11.2-NR1H3 locus in the Cohorts for Heart and Aging Research in Genetic Epidemiology Targeted Sequencing Study (CHARGE-TSS)

Autor: Jerome I. Rotter, Shuai Wang, Belinda K. Cornes, Marco Dauriz, Josée Dupuis, Alanna C. Morrison, Siscovick David, Jennifer A. Brody, Naghmeh Nikpoor, Robert Sladek, James B. Meigs, Eric Boerwinkle, Bruce M. Psaty

Publikováno v: Circulation. 129

Aim: Common variation at the polygenic 11p11.2 locus has been associated with fasting glucose (FG) and insulin (FI) in genome-wide association studies. Further insights into the genetic pathways involved in glucose homeostasis and type 2 diabetes pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b817b986e38a9f884fda64def084063
https://doi.org/10.1161/circ.129.suppl_1.48