Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Naghmeh Nikkheslat"'
Autor:
Sarah E. Herniman, Stephen J. Wood, Golam Khandaker, Paola Dazzan, Carmine M. Pariante, Nicholas M. Barnes, Carl R. Krynicki, Naghmeh Nikkheslat, Rachel C. Vincent, Alex Roberts, Annalisa Giordano, Andrew Watson, John Suckling, Thomas R. E. Barnes, Nusrat Husain, Peter B. Jones, Eileen Joyce, Stephen M. Lawrie, Shôn Lewis, Bill Deakin, Rachel Upthegrove, the BeneMin Study Team
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Attempts to delineate an immune subtype of schizophrenia have not yet led to the clear identification of potential treatment targets. An unbiased informatic approach at the level of individual immune cytokines and symptoms may reveal organis
Externí odkaz:
https://doaj.org/article/77b87667f96046caa3e615dd5523de90
Autor:
Luca Sforzini, Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Giulia Lombardo, Maria A. Nettis, Naghmeh Nikkheslat, Courtney Worrell, Zuzanna Zajkowska, Melisa Kose, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium, Carmine M. Pariante
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Compelling evidence demonstrates that some individuals suffering from major depressive disorder (MDD) exhibit increased levels of inflammation. Most studies focus on inflammation-related proteins, such as serum or plasma C-reactive protein (
Externí odkaz:
https://doaj.org/article/87d95fa49cc948a699d846cef59416df
Autor:
Giulia Lombardo, Maria Antonietta Nettis, Caitlin Hastings, Zuzanna Zajkowska, Nicole Mariani, Naghmeh Nikkheslat, Courtney Worrell, Daniela Enache, Anna McLaughlin, Melisa Kose, Anna Bogdanova, Luca Sforzini, Anthony J. Cleare, Allan H. Young, Paola Dazzan, Valeria Mondelli, Carmine M. Pariante
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100561- (2022)
Background: Inflammation is a well-known risk factor for depression. Specifically, patients who do not respond to antidepressant treatment show higher levels of inflammatory biomarkers compared with responders. Thus, several studies have investigated
Externí odkaz:
https://doaj.org/article/e3b28fd5a3d34d8ab59e01f1dd9f3ce9
Autor:
Nicholas J. Ashton, Shorena Janelidze, Ahmad Al Khleifat, Antoine Leuzy, Emma L. van der Ende, Thomas K. Karikari, Andrea L. Benedet, Tharick A. Pascoal, Alberto Lleó, Lucilla Parnetti, Daniela Galimberti, Laura Bonanni, Andrea Pilotto, Alessandro Padovani, Jan Lycke, Lenka Novakova, Markus Axelsson, Latha Velayudhan, Gil D. Rabinovici, Bruce Miller, Carmine Pariante, Naghmeh Nikkheslat, Susan M. Resnick, Madhav Thambisetty, Michael Schöll, Gorka Fernández-Eulate, Francisco J. Gil-Bea, Adolfo López de Munain, Ammar Al-Chalabi, Pedro Rosa-Neto, Andre Strydom, Per Svenningsson, Erik Stomrud, Alexander Santillo, Dag Aarsland, John C. van Swieten, Sebastian Palmqvist, Henrik Zetterberg, Kaj Blennow, Abdul Hye, Oskar Hansson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Cerebrospinal fluid neurofilament light (NfL) is a biomarker for neurodegeneration that can also be assessed in blood. Here the authors show in a validation study the potential for plasma NfL as a biomarker for several neurodegenerative diseases.
Externí odkaz:
https://doaj.org/article/5a53b0a732414b4ca05246e46c25baa3
Autor:
Maria Antonietta Nettis, Andrew J. Lawrence, Tobias Wood, Nicole Mariani, Naghmeh Nikkheslat, Giulia Lombardo, Daniela Enache, Mattia Veronese, Federico E. Turkheimer, Paola Dazzan, Carmine M. Pariante, Valeria Mondelli
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 18, Iss , Pp 100376- (2021)
Inflammatory processes in the Central Nervous System (CNS) have been proposed to mediate the association between peripheral inflammation and the development of psychiatric disorders, but we currently lack sensitive measures of CNS inflammation for hu
Externí odkaz:
https://doaj.org/article/9cdf8c76951b49fd8073de55cfc2ec79
Autor:
Naghmeh Nikkheslat
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 18, Iss , Pp 100383- (2021)
Major depressive disorder (MDD) is a common psychiatric disorder with multifactorial aetiology and complex pathophysiology. Despite availability of various pharmacological and non-pharmacological therapeutic strategies, treatment resistant depression
Externí odkaz:
https://doaj.org/article/2369bc529d63484dbb35b814e26d76e3
Autor:
Valeria Mondelli, Annamaria Cattaneo, Naghmeh Nikkheslat, Laila Souza, Annabel Walsh, Zuzanna Zajkowska, Valentina Zonca, Moira Marizzoni, Helen L. Fisher, Brandon A. Kohrt, Christian Kieling, Paola Di Meglio
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 18, Iss , Pp 100396- (2021)
Extensive research suggests a role for the innate immune system in the pathogenesis of depression, but most of the studies are conducted in adult populations, in high-income countries and mainly focus on the study of inflammatory proteins alone, whic
Externí odkaz:
https://doaj.org/article/1246efb25ee045a0ac736a77cb7ea1f0
Autor:
Sunniva Fenn-Moltu, Bill Deakin, Richard Drake, Oliver D. Howes, Stephen M. Lawrie, Shôn Lewis, Naghmeh Nikkheslat, James T.R. Walters, James H. MacCabe, Valeria Mondelli, Alice Egerton
Publikováno v:
Fenn-Moltu, S, Deakin, B, Drake, R, Howes, O D, Lawrie, S M, Lewis, S, Nikkheslat, N, Walters, J T R, MacCabe, J H, Mondelli, V & Egerton, A 2023, ' The association between peripheral inflammation, brain glutamate and antipsychotic response in Schizophrenia : Data from the STRATA collaboration ', Brain, Behavior, and Immunity, vol. 111, pp. 343-351 . https://doi.org/10.1016/j.bbi.2023.05.005
Fenn-Moltu, S, Deakin, B, Drake, R, Howes, O, Lawrie, S, Lewis, S W, Nikkheslat, N, Walters, J, Maccabe, J, Mondelli, V & Egerton, A 2023, ' The Association between Peripheral Inflammation, Brain Glutamate and Antipsychotic Response in Schizophrenia: data from the STRATA collaboration ', Brain Behavior and Immunity .
Fenn-Moltu, S, Deakin, B, Drake, R, Howes, O, Lawrie, S, Lewis, S W, Nikkheslat, N, Walters, J, Maccabe, J, Mondelli, V & Egerton, A 2023, ' The Association between Peripheral Inflammation, Brain Glutamate and Antipsychotic Response in Schizophrenia: data from the STRATA collaboration ', Brain Behavior and Immunity .
Glutamate and increased inflammation have been separately implicated in the pathophysiology of schizophrenia and the extent of clinical response to antipsychotic treatment. Despite the mechanistic links between pro-inflammatory and glutamatergic path
Autor:
S Osborne, Susan Pawlby, Alessandra Biaggi, Andrea Du Preez, Katie Hazelgrove, Susan Conroy, Vaheshta Sethna, Patricia A. Zunszain, Carmine M. Pariante, Naghmeh Nikkheslat
Publikováno v:
Osborne, S, Biaggi, A, Hazelgrove, K, Preez, A D, Nikkheslat, N, Sethna, V, Zunszain, P A, Conroy, S, Pawlby, S & Pariante, C M 2022, ' Increased maternal inflammation and poorer infant neurobehavioural competencies in women with a history of major depressive disorder from the psychiatry research and motherhood – Depression (PRAM-D) study ', Brain, Behavior, and Immunity, vol. 99, pp. 223-230 . https://doi.org/10.1016/j.bbi.2021.09.020
Introduction Stress in pregnancy is associated with adverse outcomes in offspring, and developmental programming is a potential mechanism. We have previously shown that depression in pregnancy is a valid and clearly defined stress paradigm, and both
Autor:
Neil A. Harrison, Jonathan Cavanagh, Carmine M. Pariante, Giulia Lombardo, Melisa Kose, Naghmeh Nikkheslat, Daniela Enache, Courtney Worrell, Anna McLaughlin, Edward T. Bullmore, Nicole Mariani, Philip J. Cowen, Maria A. Nettis, Zuzanna Zajkowska, Caitlin Hastings, Linda Pointon, Valeria Mondelli
Publikováno v:
BASE-Bielefeld Academic Search Engine
BackgroundDepression and overweight are each associated with abnormal immune system activation. We sought to disentangle the extent to which depressive symptoms and overweight status contributed to increased inflammation and abnormal cortisol levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5305b7a51124929c3944529d3fc480
https://www.repository.cam.ac.uk/handle/1810/318092
https://www.repository.cam.ac.uk/handle/1810/318092