Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Nagheme Thomas"'
Autor:
John A Ligon, Paul Castillo, Christina Von Roemeling, Natalie Silver, Frances Weidert, Adam Grippin, Jonathan Chardon-Robles, Eugene Hwang, Hector Mendez-Gomez, Study Staff, Elias Sayour, Sadeem Qdaisat, Dingpeng Zhang, James McGuiness, Nagheme Thomas, Anna Devries, Aida Karachi, Jianping Huang, Maryam Rahman, Elizabeth Ogando-Rivas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ff4cba9d8a244bf78c4d8b10af09b189
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223555 (2019)
Cyclin-dependent kinases 4 and 6 (CDK4/6) play critical roles in the G1 to S checkpoint of the cell cycle and have been shown to be overactive in several human cancers. Small-molecule inhibitors of CDK4/6 have demonstrated significant efficacy agains
Externí odkaz:
https://doaj.org/article/bb379871aa83476fa48e95751d477af1
Autor:
Karen Scott, Sophia Eikenberry, Aline Oliveira, Nagheme Thomas, Dominique Johnson, Caitlin Baumer-Harrison, Andrew Bryant, Annette de Kloet, Eric Krause
Publikováno v:
Physiology. 38
The worldwide prevalence of hypertension continues to rise, shortening lifespan and contributing to the risk of cardiovascular disease and stroke. Although there are numerous contributing risk factors, social adversity is believed to be one that may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1057e2e4762682ed581b2ea3eae9f0c
https://doi.org/10.1152/physiol.2023.38.s1.5733701
https://doi.org/10.1152/physiol.2023.38.s1.5733701
EXTH-92. TARGETING PRIMARY CENTRAL NERVOUS SYSTEM B CELL LYMPHOMA IGH CLONOTYPES USING NOVEL RNA-NPS
Autor:
Elizabeth Ogando-Rivas, Christina Von Roemeling, Paul Castillo, Ruixuan Liu, Hector Mendez-Gomez, Nagheme Thomas, Frances Weidert, Jonathan Chardon-Robles, Sadeem Qdaisat, Matthew Cascio, John Ligon, Jianping Huang, Duane Mitchell, Elias Sayour
Publikováno v:
Neuro-Oncology. 24:vii230-vii231
BACKGROUND Recurrent PCNSBLs represent a therapeutic challenge. Up to 60% of PCNSBL patients relapse to later face survival rates as low as 22%. Unfortunately, tumor heterogeneity and off-target effects have limited the success of immunotherapy again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb72d78fb82f4ecf4dd7d9fa24fa89e4
https://doi.org/10.1093/neuonc/noac209.890
https://doi.org/10.1093/neuonc/noac209.890
Autor:
Hector Mendez-Gomez, Anna DeVries, Brian Stover, Dingpeng Zhang, Adam Grippin, Christina Von Roemeling, Frances Weidert, Aida Karachi, Sadeem Qdaisat, Nagheme Thomas, James McGuiness, Paul Castillo, Jianping Huang, John Ligon, Natalie Silver, Patrick Kellish, Andria Doty, Sheila Carrera-Justiz, Michael Prados, Sabine Mueller, Maryam Rahman, Ashley Ghiaseddin, Duane Mitchell, Elias Sayour
Publikováno v:
Neuro-Oncology. 24:vii66-vii67
BACKGROUND Although mRNA vaccines have been deployed with great success against COVID-19, unlocking this technology against glioblastoma will necessitate new lipid-nanoparticle formulations that overcome cancer tolerance and immunosuppression. OBJECT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a81bcb22d5bfdb25ef7ac564da69419
https://doi.org/10.1093/neuonc/noac209.260
https://doi.org/10.1093/neuonc/noac209.260
Autor:
Farhad Dastmalchi, Nagheme Thomas, Matt Frain, Ghaidaa Ebrahim, Ginger Moore, Macaulay Tomdio, Hector Mendez-Gomez, Elias Sayour, Vignesh Subramaniam, Thomas Angelini, Duane Mitchell, Maryam Rahman
Publikováno v:
Neuro-Oncology. 24:vii138-vii138
INTRODUCTION Our group has developed a patented vaccine platform that combines an mRNA-nanoparticle with CXCL9 loaded polyethylene glycol (PEG) hydrogel. The HCM vaccine is given SQ and recruits a diverse immune cell population to deliver a large pay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947120a22fbc85e9670751633ad4082d
https://doi.org/10.1093/neuonc/noac209.530
https://doi.org/10.1093/neuonc/noac209.530
Autor:
Farhad Dastmalchi, Nagheme Thomas, Ghaidaa Ebrahim, Matt Frain, Ginger Moore, Hector Mendez-Gomez, Elias Sayour, Macaulay Tomdio, Vignesh Subramaniam, Thomas Angelini, Duane Mitchell, Maryam Rahman
Publikováno v:
Neuro-Oncology. 24:vii105-vii105
INTRODUCTION: Immunotherapy for GBM has resulted in limited benefits to overall survival due to the targeting of limited antigens and the hostile TME. Our group has developed a patented vaccine platform that combines an mRNA-nanoparticle with CXCL9 l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25bd1bd44589edaad510a2338b8a5dbb
https://doi.org/10.1093/neuonc/noac209.394
https://doi.org/10.1093/neuonc/noac209.394
Autor:
Matthew Frain, Ghaidaa Ebrahim, Macaulay Tomdio, Hector Mendez-Gomez, Nagheme Thomas, Aida Karachi, Farhad Dastmalchi, Catherine Flores, Duane Mitchell, Frank Bova, Maryam Rahman
Publikováno v:
Neuro-Oncology. 24:vii251-vii251
The objective of this study was to develop and test a murine system for delivery of laser interstitial thermotherapy (LITT). A system was built that allows for stereotactic placement of the laser into a mouse brain and real-time thermometry with a cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b411853f3550181f3709956232ef885
https://doi.org/10.1093/neuonc/noac209.967
https://doi.org/10.1093/neuonc/noac209.967
Autor:
James McGuiness, Frances Weidert, Dingpeng Zhang, Adam Grippin, Aida Karachi, Sadeem Qdaisat, Nagheme Thomas, Paul Castillo, Jianping Huang, John Ligon, Natalie Silver, Maryam Rahman, Eugene Hwang, Duane Mitchell, Hector Mendez-Gomez, Elias Sayour
Publikováno v:
Neuro-Oncology. 24:vii219-vii219
BACKGROUND Diffuse Intrinsic Pontine Glioma (DIPG) is uniformly fatal. Upon diagnosis, DIPG cannot be safely debulked and systemic therapies have unproven benefit. Immunotherapy can overcome these obstacles, but objective responses are rare; and canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9763876ac137fa69ea00c9085f5b48
https://doi.org/10.1093/neuonc/noac209.844
https://doi.org/10.1093/neuonc/noac209.844
Autor:
Nagheme Thomas, Son Le, Mathew Sebastian, Dan Jin, David Tran, Changwang Deng, Dongjiang Chen
Publikováno v:
Neuro Oncol
Glioblastoma (GBM) is the most common and lethal malignant brain cancer in adults. Immunotherapy has emerged as a potentially powerful approach to achieve long-term survival in patients with GBM. Antigen presenting cells (APCs) play a central role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ecd4c0c58a3d9e2aa6b5929ba3f12ca
https://europepmc.org/articles/PMC7650867/
https://europepmc.org/articles/PMC7650867/
