Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nageswaran Sivalingam"'
Publikováno v:
Apoptosis : an international journal on programmed cell death. 27(9-10)
Cancer has presented to be the most challenging disease, contributing to one in six mortalities worldwide. The current treatment regimen involves multiple rounds of chemotherapy administration, alone or in combination. The treatment has adverse effec
Autor:
Ramya Devi Kt, Nageswaran Sivalingam
Publikováno v:
Journal of Applied Biomedicine. 18:70-79
The aqueous extract of Cichorium intybus (CIE) leaves have shown the properties of protecting against pancreatic β-cell damage by streptozotocin (STZ), but the molecular mechanisms of its protection are not completely elucidated yet. Our current stu
Publikováno v:
Journal of cancer research and therapeutics. 17(6)
Consuming whole grain food has been motivated due to numerous health benefits arising from their bioactive components.This study aims to study whether the active compound extracted from Proso and Barnyard millets inhibits cell proliferation and induc
Autor:
Kaliappan Ganesan, Sruthi Sritharan, Nageswaran Sivalingam, Ab Rouf War, Sri Harsha Vedulla, Jeyan Jayarajan, Sruthy Angandoor
Publikováno v:
Molecular biology reports. 47(10)
Cancer cells require higher levels of ATP for their sustained growth, proliferation, and chemoresistance. Mitochondrial matrix protein, C1qbp is upregulated in colon cancer cell lines. It protects the mitochondria from oxidative stress, by inhibiting
Publikováno v:
Life Sciences. 278:119527
Doxorubicin or Adriamycin, is one of the most widely used chemotherapeutic drug for treating a myriad of cancers. It induces cell death through multiple intracellular targets: reactive oxygen species generation, DNA-adduct formation, topoisomerase II
Autor:
Ramamoorthi Ganesan, Jade Dhananjay Dasiram, Nageswaran Sivalingam, Venkatesan Kotteeswaran, Janani Kannan
Publikováno v:
Biomedicine & Pharmacotherapy. 86:373-380
Curcumin, a natural polyphenolic compound and it is isolated from the rhizome of Curcuma longa, have been reported to possess anticancer effect against stage I and II colon cancer. However, the effect of curcumin on colon cancer at Dukes' type C meta
Publikováno v:
Nutrition and cancer. 72(8)
In the present study, we hypothesized that the active compound extracted from Proso and Barnyard millets inhibits cell proliferation and apoptosis induction in colon cancer cell line. The bioactive compounds from these millets were purified by superc
Autor:
Ramamoorthi Ganesan, Jahnavi Bhaskaran, Samyuktha Suresh, Revanth Srinivasan, Ayushi Agarwal, Nageswaran Sivalingam, Akhila Balasubramanian, Akiladdevi Kasinathan, K B Aravind
Publikováno v:
Nutrition research (New York, N.Y.). 51
Curcumin is a natural dietary polyphenol compound that has various pharmacological activities such as antiproliferative and cancer-preventive activities on tumor cells. Indeed, the role reactive oxygen species (ROS) generated by curcumin on cell deat
Publikováno v:
Pathology oncology research : POR. 25(2)
Publikováno v:
European Journal of Pharmacology. 654:106-116
The clinical utility of nonsteroidal anti-inflammatory drugs (NSAIDs) is often limited by the adverse effects that they produce in the small intestine. Alterations in the composition and functions of the glycocalyx and brush border membranes of the r