Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Nageswara Rao Dunna"'
Autor:
Taruna Rajagopal, Arun Seshachalam, Krishna Kumar Rathnam, Srikanth Talluri, Sivaramakrishnan Venkatabalasubramanian, Nageswara Rao Dunna
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Background Homologous recombination repair (HRR) accurately repairs the DNA double-strand breaks (DSBs) and is crucial for genome stability. Genetic polymorphisms in crucial HRR pathway genes might affect genome stability and promote tumorigenesis. U
Externí odkaz:
https://doaj.org/article/dc1e492abef94ed5a095856a78bd7160
Autor:
Ram Sudheer Adluri, Mahesh Thirunavukkarasu, Lijun Zhan, Nageswara Rao Dunna, Yuzo Akita, Vaithinathan Selvaraju, Hajime Otani, Juan A Sanchez, Ye-Shih Ho, Nilanjana Maulik
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34790 (2012)
Oxidative stress plays a critical role in the pathophysiology of cardiac failure, including the modulation of neovascularization following myocardial infarction (MI). Redox molecules thioredoxin (Trx) and glutaredoxin (Grx) superfamilies actively mai
Externí odkaz:
https://doaj.org/article/a57dce194154469dbe00298c8d5ddedf
Autor:
Nageswara Rao Dunna, Solaipriya Solairaja, Satish Ramalingam, Sivaramakrishnan Venkatabalasubramanian
Publikováno v:
Endocrine, Metabolic & Immune Disorders - Drug Targets. 22:601-611
Progesterone receptor membrane component 1 (PGRMC1) is a trans-membrane evolutionarily conserved protein with a cytochrome b5 like heme/steroid binding domain. PGRMC1 clinical levels are strongly suggested to correlate with poor patient survival and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188333bb633321d74aba494c729382a0
https://doi.org/10.2174/1871530321666211130145542
https://doi.org/10.2174/1871530321666211130145542
Autor:
Arun Seshachalam, Nageswara Rao Dunna, Taruna Rajagopal, Swarna Viswanathan, Arunachalam Jothi, Krishna Kumar Rathnam, Srikanth Talluri
Publikováno v:
Molecular Biology Reports. 47:5081-5090
Identification of modifier genes predisposing to breast cancer (BC) phenotype remains a significant challenge and varies with ethnicity. The genetic variability observed in DNA repair genes may modulate the cell's ability to repair the damaged DNA an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df33113b9b5bb7d6182630a01a17367
https://doi.org/10.1007/s11033-020-05577-2
https://doi.org/10.1007/s11033-020-05577-2
Publikováno v:
Expert opinion on biological therapy. 22(5)
Bromelain belongs to the cysteine protease endopeptidase class of enzymes isolated from the stem and fruit tissue component ofThis paper presents the current state of knowledge about the isolation methods of bromelain, its safety, efficacy and tolera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7c3d1dd985fcb3aa3f6038387574ab
https://pubmed.ncbi.nlm.nih.gov/35176951
https://pubmed.ncbi.nlm.nih.gov/35176951
Autor:
Arun Seshachalam, Taruna Rajagopal, Krishna Kumar Rathnam, Nageswara Rao Dunna, Sivaramakrishnan Venkatabalasubramanian, Arunachalam Jothi, Srikanth Talluri
Publikováno v:
Molecular biology reports. 49(4)
The frequency of triple-negative breast cancer (TNBC) incidence varies among different populations, suggesting the involvement of genetic component towards TNBC development. Previous studies have reported that BRCA1/2 germline mutations confer a life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3123b04f6472bffa6d2dbd7476eb3cf2
https://pubmed.ncbi.nlm.nih.gov/35020120
https://pubmed.ncbi.nlm.nih.gov/35020120
Autor:
Nageswara Rao Dunna, Arunachalam Jothi, Srikanth Talluri, Krishna Kumar Rathnam, Arun Seshachalam, R.L. Akshaya, Taruna Rajagopal
Publikováno v:
Gene. 762
Until now, no study has reported the combined effect of genetic variants of HOTAIR and NME1 towards breast cancer (BC) pathogenesis. Hence, the aim of the present study is to determine the risk of breast cancer development with HOTAIR (rs920778 C T a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2413b6682aedbe0fa7b701745c0c1c
https://pubmed.ncbi.nlm.nih.gov/32781191
https://pubmed.ncbi.nlm.nih.gov/32781191
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 503
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic RNA (HOTAIR) is one of the most extensively studied lncRNAs found dysregulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cadc54a1152f4fe9bebaad216ef943fe
https://pubmed.ncbi.nlm.nih.gov/31901481
https://pubmed.ncbi.nlm.nih.gov/31901481
Publikováno v:
Exploring Pancreatic Metabolism and Malignancy ISBN: 9789813293922
A web of interconnected and flexible metabolic pathways helps in maintaining cellular homeostasis. These flexible metabolic pathways are further deregulated to ensure cell survival during clinical conditions such as diabetes and cancer. In fact, comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40b32e6b23ed97eea2d113f0f530ae28
https://doi.org/10.1007/978-981-32-9393-9_4
https://doi.org/10.1007/978-981-32-9393-9_4
Significance of ATM Gene Polymorphisms in Chronic Myeloid Leukemia - a Case Control Study from India
Autor:
Manjula Gorre, Nageswara Rao Dunna, Sailaja Kagita, Santhoshirani Nanchari, Sarika Jarjapu, Sugunakar Vuree, Phanni Bhushann Meka, Anuradha Cingeetham, Raghunadharao Digumarti, Sandhya Annamaneni, Vishnupriya Satti, Prajitha Edathara Mohandas
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 17:815-821
Background Development of chronic myeloid leukemia (CML) involves formation of double strand breaks (DSBs) which are initially sensed by the ataxia telangiectasia mutated (ATM) signal kinase to induce a DNA damage response (DDR). Mutations or single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45aad89b1508cd2e113f074f84689d4c
https://doi.org/10.7314/apjcp.2016.17.2.815
https://doi.org/10.7314/apjcp.2016.17.2.815