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pro vyhledávání: '"Nagesha G. Kondegowda"'
Autor:
Joanna Filipowska, Nagesha G. Kondegowda, Nancy Leon-Rivera, Sangeeta Dhawan, Rupangi C. Vasavada
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4/GPR48), a member of the GPCR (G protein-coupled receptors) superfamily, subfamily B, is a common intestinal crypt stem cell marker. It binds R-spondins/Norrin as classical ligands and
Externí odkaz:
https://doaj.org/article/be94f9f3296b45a694f8968b47c9bfc6
Publikováno v:
Journal of the Endocrine Society
Our lab has shown that RANK (Receptor activator of the NF-κB) by interacting with its ligand, RANKL, inhibits ß-cell proliferation and survival; which can be reversed by Osteoprotegerin (OPG). Recently, the G protein-coupled receptor LGR4 (leucine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d2e99bbe34f116bad241b78e92f316
http://europepmc.org/articles/PMC8089736
http://europepmc.org/articles/PMC8089736