Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Nagesh Kolishetti"'
Autor:
Adriana Yndart Arias, Kamila Vadell, Arti Vashist, Nagesh Kolishetti, Madepalli K. Lakshmana, Madhavan Nair, Juan P. Liuzzi
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundFinding new strategies to treat cognitive disorders is a challenging task. Medication must defeat the blood–brain barrier. Cannabidiol (CBD), a non-intoxicating compound of the cannabis plant, has gained recognition as a nutraceutical for
Externí odkaz:
https://doaj.org/article/c6ed513fa3034d8488e4596f37105c12
Autor:
Adriana Yndart Arias, Nagesh Kolishetti, Arti Vashist, Lakshmana Madepalli, Lorgeleys Llaguno, Madhavan Nair
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Human immunodeficiency virus (HIV) infection is associated with a chronic inflammatory stage and continuous activation of inflammasome pathway. We studied the anti-inflammatory effects of the compound cannabidiol (CBD) in comparison with Δ
Externí odkaz:
https://doaj.org/article/6a71afd8a7b5412e814ba0047b511d0a
Autor:
Sukanya Bhunia, Nagesh Kolishetti, Arti Vashist, Adriana Yndart Arias, Deborah Brooks, Madhavan Nair
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2658 (2023)
Brain cancers and neurodegenerative diseases are on the rise, treatments for central nervous system (CNS) diseases remain limited. Despite the significant advancement in drug development technology with emerging biopharmaceuticals like gene therapy o
Externí odkaz:
https://doaj.org/article/ad9790e7e99649ecb25f785c13d8fbc2
Publikováno v:
Addiction Neuroscience, Vol 4, Iss , Pp 100027- (2022)
Opioid addiction is a worldwide public health crisis stemming from the well-intentioned efforts of physicians to improve pain management in the 1990’s. The lack of knowledge behind the addictive tendencies of opioids, led to what is now known as th
Externí odkaz:
https://doaj.org/article/376c231f660e43fa92890eae485b3205
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Despite the significant advances in neurology, the cure for neurodegenerative conditions remains a formidable task to date. Among various factors arising from the complex etiology of neurodegenerative diseases, neuroinflammation and oxidative stress
Externí odkaz:
https://doaj.org/article/60a2bc61d1ef49dbb9d77acb526aa581
Autor:
Venkata Subba Rao Atluri, Sneham Tiwari, Melisa Rodriguez, Ajeet Kaushik, Adriana Yndart, Nagesh Kolishetti, Mohan Yatham, Madhavan Nair
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2020)
Alzheimer’s disease (AD) is a growing global threat to healthcare in the aging population. In the USA alone, it is estimated that one in nine persons over the age of 65 years is living with AD. The pathology is marked by the accumulation of amyloid
Externí odkaz:
https://doaj.org/article/b745ef1735b44cc895693f646bb4a5c5
Cancer cells maintain normal mitochondrial glutathione as one of the defense mechanisms to inhibit mitochondrial membrane polarization and hence apoptosis. A combinational therapeutic modality Platin-Cbl, a prodrug of FDA-approved chemotherapeutic ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a0789b45a9197074ec1d325cfdbe13
https://doi.org/10.1158/1535-7163.c.6538749.v1
https://doi.org/10.1158/1535-7163.c.6538749.v1
Supplementary Materials and Methods. Figure S1. 1H NMR of Platin-Cbl using DMSO-d6; Figure S2. 13C NMR of Platin-Cbl using DMSO-d6; Figure S3. 195Pt NMR of Platin-Cbl using DMSO-d6; Figure S4. HRMS-ESI of Platin-Cbl along with observed and calculated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafe3ccc3bedca6b9c15dd071fe20d6c
https://doi.org/10.1158/1535-7163.22507647.v1
https://doi.org/10.1158/1535-7163.22507647.v1
Publikováno v:
Acc Mater Res
Since its discovery in 1965, the inorganic drug cisplatin has become a mainstay of cancer therapies and has inspired many platinum (Pt)-based compounds to solve various issues of toxicity and limitations associated with the original cisplatin. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e807b212b3106eb3f84e6ba748f8407
https://doi.org/10.1021/accountsmr.1c00178
https://doi.org/10.1021/accountsmr.1c00178
Publikováno v:
Biomacromolecules
As the COVID-19 pandemic has continued to spread, studies have shown that hospitalized COVID-19 patients are at significant risk for developing acute kidney injury (AKI), which can cause increased morbidity, the need for dialysis treatment, chronic k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fd777875d6712e1a0e763468d10cec
https://doi.org/10.1021/acs.biomac.1c00799
https://doi.org/10.1021/acs.biomac.1c00799