Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Nagendran Tharmalingam"'
Autor:
Manimozhi Dhivya, Govindasamy Senthilraja, Nagendran Tharmalingam, Sankarasubramanian Harish, Kalaiselvan Saravanakumari, Theerthagiri Anand, Sundararajan Thiruvudainambi
Publikováno v:
PeerJ, Vol 11, p e16258 (2023)
Foxtail millet blast caused by Magnaporthe grisea is becoming a severe problem in foxtail millet growing regions of India. The genetic diversity and population structure of foxtail millet infecting M. grisea is crucial for developing effective manage
Externí odkaz:
https://doaj.org/article/b091c73e67d34bba83d470f4c6aafd8e
Autor:
Nagendran Tharmalingam, Shi Xu, Lewis Oscar Felix, Biswajit Roy, Ming Xian, Eleftherios Mylonakis, Beth Burgwyn Fuchs
Publikováno v:
Frontiers in Antibiotics, Vol 2 (2023)
IntroductionThere is a significant need for new antimicrobial compounds that are effective against drug-resistant microbes. Thioredoxin reductase (TrxR) is critical in redox homeostasis and was identified as a potential drug target and confirmed thro
Externí odkaz:
https://doaj.org/article/5f8c6316040741448ba02e55f99dcb81
Autor:
LewisOscar Felix, Cutler Whitely, Nagendran Tharmalingam, Biswajit Mishra, Noel Vera-Gonzalez, Eleftherios Mylonakis, Anita Shukla, Beth Burgwyn Fuchs
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Microbe entry through catheter ports can lead to biofilm accumulation and complications from catheter-related bloodstream infection and ultimately require antimicrobial treatment and catheter replacement. Although strides have been made with microbia
Externí odkaz:
https://doaj.org/article/34629ca83fbb4c729ccb199222a79b14
Publikováno v:
Journal of Infection and Public Health, Vol 13, Iss 10, Pp 1501-1507 (2020)
Background: Staphylococcus aureus (S. aureus) is one of the leading causes of community and hospital acquired infections globally. The objective of the study was to assess the prevalence, study the carriage of antibiotic resistance genes and evaluate
Externí odkaz:
https://doaj.org/article/403b1820e09a4e578f8aacc501789276
Autor:
Arulsamy Kulandaisamy, Murugesan Panneerselvam, Rajadurai Vijay Solomon, Madhavan Jaccob, Jaganathan Ramakrishnan, Kumaradhas Poomani, Muralikannan Maruthamuthu, Nagendran Tharmalingam
Publikováno v:
Molecules, Vol 27, Iss 12, p 3962 (2022)
The high expression of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) mRNA has been found in breast cancer tissues and endometriosis. The current research focuses on preparing a range of organic molecules as 17β-HSD1 inhibitors. Among them, th
Externí odkaz:
https://doaj.org/article/5d54b635354a4d46974c92f1eac833b2
Autor:
Fernanda Cristina Possamai Rossatto, Nagendran Tharmalingam, Iliana E. Escobar, Pedro Alves d’Azevedo, Karine Rigon Zimmer, Eleftherios Mylonakis
Publikováno v:
Journal of Fungi, Vol 7, Iss 9, p 763 (2021)
Candida auris is an emerging healthcare-associated fungal pathogen that has become a serious global health threat. Current treatment options are limited due to drug resistance. New therapeutic strategies are required to target this organism and its p
Externí odkaz:
https://doaj.org/article/56dd1220679449c29e8cc6af7ef76463
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Antimicrobial drug discovery against drug-resistant bacteria is an urgent need. Beyond agents with direct antibacterial activity, anti-virulent molecules may also be viable compounds to defend against bacterial pathogenesis. Using a high throughput s
Externí odkaz:
https://doaj.org/article/5addca3b8d654b589f253e9a6b962651
Autor:
Hanyang Liu, Shashank Shukla, Noel Vera-González, Nagendran Tharmalingam, Eleftherios Mylonakis, Beth Burgwyn Fuchs, Anita Shukla
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Intravascular catheter related bloodstream infections (CRBSIs) are a leading cause of hospital-acquired infections worldwide, resulting not only in the burden of cost and morbidity for patients but also in the over-consumption of medical resources fo
Externí odkaz:
https://doaj.org/article/d7afcaf729f74ac180e7ec7e96bb82fb
Autor:
Rajamohammed Khader, Nagendran Tharmalingam, Biswajit Mishra, LewisOscar Felix, Frederick M. Ausubel, Michael J. Kelso, Eleftherios Mylonakis
Publikováno v:
Antibiotics, Vol 9, Iss 8, p 449 (2020)
There is a significant need to combat the growing challenge of antibacterial drug resistance. We have previously developed a whole-animal dual-screening platform that first used the nematode Caenorhabditis elegans, to identify low-toxicity antibacter
Externí odkaz:
https://doaj.org/article/221f0128c81d4ef1ab38bea2d3818438
Autor:
Lana Ivone Barreto Cruz, Larissa Ferreira Finamore Lopes, Felipe de Camargo Ribeiro, Nívea Pereira de Sá, Cleudiomar Inácio Lino, Nagendran Tharmalingam, Renata Barbosa de Oliveira, Carlos Augusto Rosa, Eleftherios Mylonakis, Beth Burgwyn Fuchs, Susana Johann
Publikováno v:
Journal of Fungi, Vol 4, Iss 4, p 134 (2018)
Candidiasis is an opportunistic fungal infection with Candida albicans being the most frequently isolated species. Treatment of these infections is challenging due to resistance that can develop during therapy, and the limited number of available ant
Externí odkaz:
https://doaj.org/article/f40af27effc346159b46797267611c06