Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nagender, Ledala"'
Autor:
Spencer Coleman, Katrin Unterhauser, Karim Rezaul, Nagender Ledala, Stephanie Lesmes, Melissa J. Caimano, Yanjiao Zhou, Eric Jackson, Dawn Gratalo, Mark D. Driscoll, Adam P. Matson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Intestinal colonization with Klebsiella has been linked to necrotizing enterocolitis (NEC), but methods of analysis usually failed to discriminate Klebsiella species or strains. A novel ~ 2500-base amplicon (StrainID) that spans the 16S and
Externí odkaz:
https://doaj.org/article/7e2526d148b143d7959f30703288e165
Autor:
Sara Paveglio, Nagender Ledala, Karim Rezaul, Qingqi Lin, Yanjiao Zhou, Anthony A. Provatas, Erin Bennett, Tristan Lindberg, Melissa Caimano, Adam P. Matson
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1321-1329 (2020)
ABSTRACTNecrotizing enterocolitis (NEC) is a devastating intestinal inflammatory disease of premature infants associated with gut bacterial dysbiosis. Using 16S rRNA-based methods, our laboratory identified an unclassified Enterobacteriaceae sequence
Externí odkaz:
https://doaj.org/article/ba2f0102f5df48a4b4afd679be31eea8
Autor:
Nagender Ledala, Mishika Malik, Karim Rezaul, Sara Paveglio, Anthony Provatas, Aaron Kiel, Melissa Caimano, Yanjiao Zhou, Jonathan Lindgren, Kristyna Krasulova, Peter Illes, Zdeněk Dvořák, Sandhya Kortagere, Sabine Kienesberger, Amar Cosic, Lisa Pöltl, Ellen L. Zechner, Subho Ghosh, Sridhar Mani, Justin D. Radolf, Adam P. Matson
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Gastrointestinal microbes respond to biochemical metabolites that coordinate their behaviors. Here, we demonstrate that bacterial indole functions as a multifactorial mitigator of Klebsiella grimontii and Klebsiella oxytoca pathogenicity. Th
Externí odkaz:
https://doaj.org/article/fe63cc8ff8ca415a9500fb87f0e2d592
Autor:
Sara, Paveglio, Nagender, Ledala, Karim, Rezaul, Qingqi, Lin, Yanjiao, Zhou, Anthony A, Provatas, Erin, Bennett, Tristan, Lindberg, Melissa, Caimano, Adam P, Matson
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Necrotizing enterocolitis (NEC) is a devastating intestinal inflammatory disease of premature infants associated with gut bacterial dysbiosis. Using 16S rRNA-based methods, our laboratory identified an unclassified Enterobacteriaceae sequence (NEC_un
Autor:
Qingqi Lin, Erin Bennett, Melissa J. Caimano, Adam P. Matson, Tristan P. Lindberg, Anthony A. Provatas, Yanjiao Zhou, Nagender Ledala, Sara A. Paveglio, Karim Rezaul
Necrotizing enterocolitis (NEC) is a devastating intestinal inflammatory disease of premature infants associated with gut bacterial dysbiosis. Using 16S rRNA-based methods, our laboratory identified an unclassified Enterobacteriaceae sequence (NEC_un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42dca820369ccf2b7d813233ba80357d
Autor:
Julie A. Morrissey, Brian J. Wilkinson, Arunachalam Muthaiyan, Emma Tarrant, Mrittika Sengupta, Joanne Purves, Robert Stephenson, Nagender Ledala, Alan Cockayne, Miranda Johnson, Peter H. Williams, Radheshyam K. Jayaswal
Publikováno v:
International Journal of Medical Microbiology. 301:44-52
Our previous studies showed that both Sae and Fur are required for the induction of eap and emp expression in low iron. In this study, we show that expression of sae is also iron-regulated, as sae expression is activated by Fur in low iron. We also d
Publikováno v:
Microbiology. 153:1103-1111
Iron is essential for the survival of almost all organisms, although excess iron can result in the generation of free radicals which are toxic to cells. To avoid the toxic effects of free radicals, the concentration of intracellular iron is generally
Publikováno v:
International Journal of Antimicrobial Agents. 27:518-524
Autolysins are peptidoglycan hydrolases involved in cell growth and cell lysis. Atl is an important autolysin of Staphylococcus aureus and is essential for penicillin-induced autolysis. The objective of our study was to examine the effect of oxacilli
Publikováno v:
Journal of bacteriology. 196(12)
Staphylococcus aureus is a prominent nosocomial pathogen and a major cause of biomaterial-associated infections. The success of S. aureus as a pathogen is due in part to its ability to adapt to stressful environments. As an example, the transition fr
Autor:
Sutthirat Sitthisak, Brian J. Wilkinson, Rebecca J. Steidl, Robert Stephenson, Stacy L. Pearson, Radheshyam K. Jayaswal, Nagender Ledala
Publikováno v:
Antimicrobial Agents and Chemotherapy. 52:2923-2925
lacZ fusion strains were constructed using the promoters of five cell wall stress stimulon genes: pbp2 , tcaA , vraSR , sgtB , and lytR . All fusion strains were induced only in the presence of cell wall-active antibiotics, suggesting the potential o