Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nagasurya Prakash Padala"'
Autor:
Parusharamulu Molgara, Arunkumar Manoharan, Nagasurya Prakash Padala, Gopinadh Bhyrapuneni, Veera Raghava Chowdary Palacharla, Ramakrishna Nirogi
Publikováno v:
Xenobiotica. 50:1228-1235
The use of IBH-5 decreased the kdeg values and increased the half-life of the compounds PNZ, TCP, Cpd I and Cpd II with kdeg values of 1.10 × 10−4 s− 1 (t1/2 = 115 min), 4 × 10−5 s−1 (t1/2 = 289 mi...
Autor:
Ramakrishna, Nirogi, Parusharamulu, Molgara, Gopinadh, Bhyrapuneni, Arunkumar, Manoharan, Nagasurya Prakash, Padala, Veera Raghava Chowdary, Palacharla
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 50(10)
The use of IBH-5 decreased the
Autor:
Nagasurya Prakash Padala, Gopinadh Bhyrapuneni, Prathyusha Chunduru, Jagadeesh Babu Thentu, Hanumanth Rao Pantangi, Ramakrishna Nirogi
Publikováno v:
Neurochemistry International. 145:105006
Monoamine oxidase (MAO) enzymes, type A and B metabolise the amine neurotransmitters of the body. Selective inhibition of either enzyme is an approach for treating neurodegenerative and stress-induced disorders, and inhibition of an enzyme is proport
Autor:
Rajesh Kumar Boggavarapu, Devender Reddy Ajjala, Arunkumar Manoharan, Ranjith Kumar Ponnamaneni, Venkatesham Uthukam, Raghava Choudary Palacharla, Ramakrishna Nirogi, Nagasurya Prakash Padala, Gopinadh Bhyrapuneni
Publikováno v:
European Journal of Pharmaceutical Sciences. 101:80-89
The objective of the study was to determine the effect of fatty acids on CYP enzymes and the effect of BSA on intrinsic clearance of probe substrates. The inhibitory effect of thirteen fatty acids including saturated, mono-unsaturated and polyunsatur
Autor:
Arunkumar Manoharan, Nageswara Rao Muddana, Ramkumar Subramanian, Devender Reddy Ajjala, Veera Raghava Chowdary Palacharla, Abdul Rasheed Mohammed, Anil Shinde, Gopinadh Bhyrapuneni, Ramakrishna Nirogi, Nagasurya Prakash Padala
Publikováno v:
European Journal of Pharmaceutical Sciences. 152:105425
SUVN-G3031 is a potent and selective inverse agonist of Histmine-3 (H3) receptor that is being investigated for the treatment of narcolepsy. SUVN-G3031 has high passive permeability, not a substrate for P-glycoprotein, has high plasma unbound fractio
Autor:
Abdul Rasheed Mohammed, Ramakrishna Nirogi, Gopinadh Bhyrapuneni, Jagadeesh Babu Thentu, Devender Reddy Ajjala, Nagasurya Prakash Padala, Raghupathi Aleti
Publikováno v:
Journal of receptor and signal transduction research. 38(4)
The use of liquid chromatography coupled with mass spectrometry (LC-MS/MS) is advantageous in in-vivo receptor occupancy assays at pre-clinical drug developmental stages. Relatively, its application is effective in terms of high throughput, data repr
Autor:
Rajesh Kumar Boggavarapu, Ramakrishna Nirogi, Nagasurya Prakash Padala, Praveen Kunduru, Devender Reddy Ajjala
Publikováno v:
Bioanalysis. 9(7)
Background: Incurred sample reanalysis (ISR) is an in-study validation parameter, which reinforces that the validated bioanalytical methods are reproducible. ISR of whole blood samples is complex when the test compounds can interconvert, ex vivo. Fin
Autor:
Ramakrishna Nirogi, Raghava Choudary Palacharla, Ilayaraja Kalaikadhiban, Venkatesham Uthukam, Arun Kumar Manoharan, Rajesh Kumar Boggavarapu, Nagasurya Prakash Padala
Publikováno v:
Drug Metabolism and Pharmacokinetics. 33:S47-S48
Autor:
Nagasurya Prakash Padala, Harikrishna Kalyani, Gopinadh Bhyrapuneni, Mohammed Abdul Rasheed, Ramakrishna Nirogi, Rajinikanth Dyavarashetty, Jagadeesh Babu Thentu, Rajesh Kumar Boggavarapu, Devender Reddy Ajjala
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Rajesh Kumar Boggavarapu, Devender Reddy Ajjala, Praveen Kunduru, Nagasurya Prakash Padala, Ramakrishna Nirogi, Raghava Choudary Palacharla
Publikováno v:
Drug Metabolism and Pharmacokinetics. 33:S63