Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nagaraju, Mupparapu"'
Autor:
Nagaraju Mupparapu, Shahnawaz Khan, Pankaj Bandhoria, Shunmuganarayanan Athimoolam, Qazi Naveed Ahmed
Publikováno v:
ACS Omega, Vol 3, Iss 5, Pp 5445-5452 (2018)
Externí odkaz:
https://doaj.org/article/074a38b9861943899c002f02f43783c6
Autor:
Ahmed R Aoun, Nagaraju Mupparapu, Diem N Nguyen, Tae Ho Kim, Christopher M. Nguyen, Zhengfeiyue Pan, Sherif I. Elshahawi
Publikováno v:
ChemCatChem
Indole is a significant structural moiety and functionalization of the C–H bond in indole-containing molecules expands their chemical space, and modifies their properties and/or activities. Indole prenyltransferases (IPTs) catalyze the direct regio
Autor:
Suresh Kumar, Santosh Kumar Guru, Anup Singh Pathania, Nagaraju Mupparapu, Ajay Kumar, Fayaz Malik, Sandip B. Bharate, Qazi Naveed Ahmed, Ram A. Vishwakarma, Shashi Bhushan
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 1013-1025 (2014)
Crosstalk between apoptosis and autophagy is budding as one of the novel strategies in the cancer therapeutics. The present study tinted toward the interdependence of autophagy and apoptosis induce by a novel quinazolinone derivative 2,3-dihydro-2-(q
Externí odkaz:
https://doaj.org/article/a8c0d634550a4cc49254ffe08ab72d29
Publikováno v:
Chemistry – A European Journal. 27:4176-4182
Daptomycin (DAP) is a calcium (Ca2+ )-dependent FDA-approved antibiotic drug for the treatment of Gram-positive infections. It possesses a complex pharmacophore hampering derivatization and/or synthesis of analogues. To mimic the Ca2+ -binding effect
Autor:
Sandip Bibishan Bharate, Nagaraju Mupparapu, Sudhakar Manda, Jaideep B. Bharate, Ramesh Mudududdla, Rammohan R. Yadav, Ram A. Vishwakarma
Publikováno v:
ARKIVOC, Vol 2012, Iss 8, Pp 308-318 (2012)
Externí odkaz:
https://doaj.org/article/e1738c8a228346cf8c02116e1d9ece5b
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(20)
The late-stage functionalization of indole- and tryptophan-containing compounds with reactive moieties facilitates downstream diversification and leads to changes in their biological properties. Here, the synthesis of two hydroxy-bearing allyl pyroph
Autor:
Pankaj Bandhoria, Nagaraju Mupparapu, Shunmuganarayanan Athimoolam, Shahnawaz Khan, Qazi Naveed Ahmed
Publikováno v:
ACS Omega
ACS Omega, Vol 3, Iss 5, Pp 5445-5452 (2018)
ACS Omega, Vol 3, Iss 5, Pp 5445-5452 (2018)
A novel one-pot tandem process involving Knoevenagel condensation, Michael addition, selective amidation, and Paal–Knorr cyclization to diverse functionalized 3-hydroxy-2-furanyl-acrylamides from simple 2-oxoaldehydes and aroylacetonitriles was pre
Autor:
Mubashir J. Mintoo, Nagaraju Mupparapu, Mohmmad Afzal Zargar, Asif Khurshid Qazi, Girish Mahajan, Ashok Kumar, Abid Hamid, Sandip B. Bharate, Dilip M. Mondhe, Parduman R. Sharma, Ram A. Vishwakarma, Qazi Naveed Ahmed, Shashank K. Singh, Aashiq Hussain
Publikováno v:
Molecular Carcinogenesis. 55:2135-2155
Phosphatidylinositol-3-kinase (PI3K) pathway deregulation is responsible for initiation, chemo-resistance, and poor prognosis of colorectal cancer (CRC). Therefore, PI3K pathway inhibition can provide a plausible way of attaining CRC treatment. We re
Autor:
Manoj Khushwaha, Parvinder Pal Singh, Qazi Naveed Ahmed, Nagaraju Mupparapu, Ajai Prakash Gupta
Publikováno v:
The Journal of Organic Chemistry. 80:11588-11592
An efficient metal-free method for the synthesis of α-ketothioesters is described for the first time. This reaction features the ability of pyrrolidine to fine-tune the reaction between 2-oxoaldehyde and thiols through iminium to the desired product