Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nagaraj D. Halemani"'
Autor:
Dionne Tannetta, Michiya Matsusaki, Paul Verkade, Simon Grant, John D. Aplin, Gavin Collett, Jon Hanley, Aman Sood, Fiona Day, Nagaraj D. Halemani, Catherine Murdoch-Davis, Akihiro Nishiguchi, Jennifer McGarvey, Ian L. Sargent, Helena Kemp, Mitsuru Akashi, Catherine E. Gilmore, C. Patrick Case
Publikováno v:
Biomaterials. 192:140-148
Fetal development may be compromised by adverse events at the placental interface between mother and fetus. However, it is still unclear how the communication between mother and fetus occurs through the placenta. In vitro - models of the human placen
Autor:
Robert Keehan, Roberta Goodall, Oliver Beaumont, Akihiro Nishiguchi, Lizeth Lacharme-Lora, Michele Giugliano, Michiya Matsusaki, Christopher Coyle, Hiroyoshi Y. Tanaka, Tracey Masters, Nicki Cohen, Jon Hanley, Veronica H.L. Leinster, C. Patrick Case, Andrew D. Randall, Kristian Aquilina, Ian L. Sargent, Katja Simon, Nagaraj D. Halemani, Jennifer McGarvey, William Ind, Helena Kemp, Simon Grant, Emma Scull-Brown, Sharan Athwal, Aman Sood, Daniel J Curtis, Mitsuru Akashi, Rocco A Barone, Jon D. Lane, Thomas E. Phillips, Gavin Collett, Mitsunobu R. Kano, Leila Cornes, Xun Liu, Marianne Thoresen, Dionne Tannetta
Publikováno v:
Experimental neurology
Some psychiatric diseases in children and young adults are thought to originate from adverse exposures during fetal life, including hypoxia and hypoxia/reoxygenation. The mechanism is not understood. Several authors have emphasised that the placenta
Autor:
Jonathan G. Hanley, Marcio Baptista, Alexei M. Bygrave, Christine M Rostosky, Ira Milosevic, Gabrielle T. Parkinson, Maria Fiuza, Nagaraj D. Halemani
Publikováno v:
The Journal of Cell Biology
Fiuza, M, Rostosky, C, Parkinson, G, Bygrave, A, Halemani, N, Baptista, M, Milosevic, I & Hanley, J 2017, ' PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin ', Journal of Cell Biology, vol. 216, no. 10, pp. 3323-3338 . https://doi.org/10.1083/jcb.201701034
Fiuza, M, Rostosky, C, Parkinson, G, Bygrave, A, Halemani, N, Baptista, M, Milosevic, I & Hanley, J 2017, ' PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin ', Journal of Cell Biology, vol. 216, no. 10, pp. 3323-3338 . https://doi.org/10.1083/jcb.201701034
Fiuza et al. report that PICK1 localizes to clathrin-coated pits and makes direct, functional interactions with the endocytic adapter complex AP2 and dynamin. The PICK1–AP2 interaction is required for clustering AMPA receptors at endocytic sites an
Autor:
Nagaraj D. Halemani, Arne Schreiber, Reinhard Jahn, Thorsten Lang, Felipe E. Zilly, Luis Spitta, David Walrafen
Publikováno v:
The EMBO Journal. 30:1209-1220
Membrane proteins and membrane lipids are frequently organized in submicron-sized domains within cellular membranes. Factors thought to be responsible for domain formation include lipid–lipid interactions, lipid–protein interactions and protein
Autor:
Rory R. Duncan, Silvio O. Rizzoli, Ondřej Mandula, David Moulton, Colin Rickman, Nagaraj D. Halemani, Claire N. Medine, Luke H. Chamberlain, Alison R. Dun
Publikováno v:
The Journal of Biological Chemistry
Rickman, C, Medine, C N, Dun, A R, Moulton, D J, Mandula, O, Halemani, N D, Rizzoli, S O, Chamberlain, L H & Duncan, R R 2010, ' t-SNARE Protein Conformations Patterned by the Lipid Microenvironment ', Journal of Biological Chemistry, vol. 285, no. 18, pp. 13535-13541 . https://doi.org/10.1074/jbc.M109.091058
Rickman, C, Medine, C N, Dun, A R, Moulton, D J, Mandula, O, Halemani, N D, Rizzoli, S O, Chamberlain, L H & Duncan, R R 2010, ' t-SNARE Protein Conformations Patterned by the Lipid Microenvironment ', Journal of Biological Chemistry, vol. 285, no. 18, pp. 13535-13541 . https://doi.org/10.1074/jbc.M109.091058
The spatial distribution of the target (t-) SNARE proteins (syntaxin and SNAP-25) on the plasma membrane has been extensively characterized. However, the protein conformations and interactions of the two t-SNAREs in situ remain poorly defined. By usi
Publikováno v:
Progress in Lipid Research. 47:461-469
For membrane fusion to occur, opposed lipid bilayers initially establish a fusion pore, often followed by complete mixing of the fusing membranes. Contemporary views suggest that during fusion lipid bilayers are continuous passive platforms that are
Autor:
Nagaraj D, Halemani
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 29(14)
Autor:
Felipe E, Zilly, Nagaraj D, Halemani, David, Walrafen, Luis, Spitta, Arne, Schreiber, Reinhard, Jahn, Thorsten, Lang
Publikováno v:
The EMBO journal. 30(7)
Membrane proteins and membrane lipids are frequently organized in submicron-sized domains within cellular membranes. Factors thought to be responsible for domain formation include lipid-lipid interactions, lipid-protein interactions and protein-prote
Publikováno v:
Traffic (Copenhagen, Denmark). 11(3)
SNAREs are clustered membrane proteins essential for intracellular fusion steps. During fusion, three to four SNAREs with a Q(a)-, Q(b)-, Q(c)- and R-SNARE-motif form a complex. The core complex represents a Q(a)Q(b)Q(c)R-SNARE-motif bundle, most cer
Autor:
Nagaraj D. Halemani
Publikováno v:
Movement Disorders. 29:1757-1757