Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nagabhushana Nayak"'
Publikováno v:
Journal of Fluorine Chemistry. 183:59-68
In an attempt to develop newer antitubercular and antibacterial agents against the increasing bacterial resistance, we have designed new quinoline–pyrazole analogs ( 8a – u ) following the molecular hybridization approach. The structure of one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a58d6ed6697c89fc5771bccab022dafd
https://doi.org/10.1016/j.jfluchem.2016.01.011
https://doi.org/10.1016/j.jfluchem.2016.01.011
Autor:
Perumal Yogeeswari, Nagabhushana Nayak, Dharmarajan Sriram, Udayakumar Dalimba, Jurupula Ramprasad
Publikováno v:
Chinese Chemical Letters. 27:365-369
This article demonstrates the synthesis, characterization and the study of in vitro antitubercular activities of twenty four new N -(4-(5-aryl-3-(5-methyl-1,3,4-oxadiazol-2-yl)-1 H -pyrazol-1-yl)phenyl)-4-amide derivatives ( 8a–x ). The antitubercu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e6b21a74eaa8f832e7a678e72aab691
https://doi.org/10.1016/j.cclet.2016.01.015
https://doi.org/10.1016/j.cclet.2016.01.015
Autor:
Jurupula Ramprasad, Perumal Yogeeswari, Udayakumar Dalimba, Nagabhushana Nayak, Dharmarajan Sriram
Publikováno v:
MedChemComm. 7:338-344
In this paper, we report the facile and efficient one-pot three-component synthesis of 1-((6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl)methylene)-2-(4-phenylthiazol-2-yl)hydrazine derivatives (5a–w) using an ionic liquid, namely 1-butyl-3-methylim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ee7d92281b11d61a70277e2ac02a6b
https://doi.org/10.1039/c5md00346f
https://doi.org/10.1039/c5md00346f
Publikováno v:
European Journal of Medicinal Chemistry. 106:75-84
A new library of phenothiazine and 1,3,4-thiadiazole hybrid derivatives (5a-u) was designed based on the molecular hybridization approach and the molecules were synthesized in excellent yields using a facile single-step chloro-amine coupling reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c06b0fade8e8446216d5a5435b8725c
https://doi.org/10.1016/j.ejmech.2015.10.035
https://doi.org/10.1016/j.ejmech.2015.10.035
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5540-5545
With the aim of developing promising antitubercular and antibacterial leads, we have designed and synthesized a new series of isonicotinohydrazide based pyrazole derivatives (5a-r). All new derivatives (4a-b and 5a-r) were screened for in vitro antim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39cbb7841410ca3c34e63c19084f86da
https://doi.org/10.1016/j.bmcl.2015.10.057
https://doi.org/10.1016/j.bmcl.2015.10.057
Publikováno v:
Journal of Heterocyclic Chemistry. 54:171-182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3b7ca4315e21ef779343e5623fb2e5e
https://doi.org/10.1002/jhet.2564
https://doi.org/10.1002/jhet.2564
Autor:
Dharmarajan Sriram, H. S. Santosh Kumar, S. K. Peethambar, Perumal Yogeeswari, Jurupula Ramprasad, Nagabhushana Nayak, Rajeshwara N. Achur, Udayakumar Dalimba
Publikováno v:
Research on Chemical Intermediates. 42:3721-3741
A new series of pyrazole-based 1,2,3-triazole derivatives (6a–x) were synthesized by employing click reaction using a 2:1 mixture of PEG-400 and water as green solvent. The synthesized intermediate and final compounds were characterized by 1H NMR,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ed76d83135de1f3b3da59791e76cfc8
https://doi.org/10.1007/s11164-015-2241-9
https://doi.org/10.1007/s11164-015-2241-9
Autor:
Dharmarajan Sriram, Rajeshwara N. Achur, H. S. Santosh Kumar, Nagabhushana Nayak, Jurupula Ramprasad, S. K. Peethambar, Perumal Yogeeswari, Udayakumar Dalimba
Publikováno v:
European Journal of Medicinal Chemistry. 95:49-63
In this report, we describe the synthesis and biological evaluation of a new series of 2-(imidazo[2,1-b][1,3,4]thiadiazol-5-yl)-1H-benzimidazole derivatives (5a-ac). The molecules were analyzed by 1H NMR, 13C NMR, mass spectral and elemental data. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01c6e1ae02cd1f86c2cf150271a28a5
https://doi.org/10.1016/j.ejmech.2015.03.024
https://doi.org/10.1016/j.ejmech.2015.03.024
Autor:
Perumal Yogeeswari, Jurupula Ramprasad, Nagabhushana Nayak, Dharmarajan Sriram, Udayakumar Dalimba
Publikováno v:
ChemInform. 47
A new series of triazole-imidazo[2,1-b][1,3,4]thiadiazole hybrids (6a-s, 7a) were designed by a molecular hybridisation approach and the target molecules were synthesized via one pot click chemistry protocol. All the intermediates and final molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a5e80a9c9659fe6fe18dc38217b7ee2
https://doi.org/10.1002/chin.201605027
https://doi.org/10.1002/chin.201605027
Autor:
Perumal Yogeeswari, Jurupula Ramprasad, Dharmarajan Sriram, Nagabhushana Nayak, Udayakumar Dalimba
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(19)
A new series of triazole-imidazo[2,1-b][1,3,4]thiadiazole hybrids (6a-s, 7a) were designed by a molecular hybridisation approach and the target molecules were synthesized via one pot click chemistry protocol. All the intermediates and final molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c5292fcb0514927ee7b785e6c8d764
https://pubmed.ncbi.nlm.nih.gov/26298500
https://pubmed.ncbi.nlm.nih.gov/26298500