Germline biomarkers predict toxicity to anti-PD1/PDL1 checkpoint therapy

Autor: Santosh Kesari, Jose Carrillo, Alexandra Drakaki, Joanne Weidhaas, Mark Scholz, Nicholas Marco, Aaron W Scheffler, Anusha Kalbasi, Kirk Wilenius, Emily Rietdorf, Jaya Gill, Mara Heilig, Caroline Desler, Robert K Chin, Tania Kaprealian, Susan McCloskey, Ann Raldow, Naga P Raja, Donatello Telesca

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)

Background There is great interest in finding ways to identify patients who will develop toxicity to cancer therapies. This has become especially pressing in the era of immune therapy, where toxicity can be long-lasting and life-altering, and primari

Externí odkaz: https://doaj.org/article/e2019815fc4c4bd1be2b11529a99a478

Germline biomarkers predict toxicity to anti-PD1/PDL1 checkpoint therapy

Autor: Joanne Weidhaas, Nicholas Marco, Aaron W Scheffler, Anusha Kalbasi, Kirk Wilenius, Emily Rietdorf, Jaya Gill, Mara Heilig, Caroline Desler, Robert K Chin, Tania Kaprealian, Susan McCloskey, Ann Raldow, Naga P Raja, Santosh Kesari, Jose Carrillo, Alexandra Drakaki, Mark Scholz, Donatello Telesca

Publikováno v: Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Journal for immunotherapy of cancer, vol 10, iss 2

BackgroundThere is great interest in finding ways to identify patients who will develop toxicity to cancer therapies. This has become especially pressing in the era of immune therapy, where toxicity can be long-lasting and life-altering, and primaril

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057217867d2e1f09df31d2eaff05f0aa
https://doi.org/10.1136/jitc-2021-003625