Zobrazeno 1 - 10
of 685
pro vyhledávání: '"Naga Chalasani"'
Autor:
Archita P. Desai, Swetha Parvataneni, Shannon M. Knapp, Lauren D. Nephew, Naga Chalasani, Marwan S. Ghabril, Eric S. Orman
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100955- (2024)
Background & Aims: The hospital frailty risk score (HFRS) identifies older patients at risk of poor outcomes and may have value in cirrhosis. We compared the Charlson (CCI), Elixhauser (ECI), and cirrhosis (CirCom) comorbidity indices with the HFRS i
Externí odkaz:
https://doaj.org/article/53a52c36d61b4b5c9c21af9047529b0c
Autor:
Nicholas R. Powell, Tiebing Liang, Joseph Ipe, Sha Cao, Todd C. Skaar, Zeruesenay Desta, Hui-Rong Qian, Philip J. Ebert, Yu Chen, Melissa K. Thomas, Naga Chalasani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
This study characterizes expression of pharmacogenes across the histological NAFLD severity spectrum. Here, the authors show the downregulation of CYP2C19 in NAFLD which supports developing personalized medicine approaches for drugs sensitive to meta
Externí odkaz:
https://doaj.org/article/a90be45cc8cb455db34c7afe0b5d1181
Autor:
Raj Vuppalanchi, Vijay Are, Alison Telford, Liam Young, Sofia Mouchti, Carlos Ferreira, Carla Kettler, Mark Gromski, Fatih Akisik, Naga Chalasani
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100834- (2023)
Background & Aims: Magnetic resonance cholangiopancreatography (MRCP) for evaluation of biliary disease currently relies on subjective assessment with limited prognostic value because of the lack of quantitative metrics. Artificial intelligence-enabl
Externí odkaz:
https://doaj.org/article/9905a40d1eaa4903b1a7b8610d5f64dd
Autor:
Shengmin Yan, Jun Zhou, Hao Zhang, Zhen Lin, Bilon Khambu, Gang Liu, Michelle Ma, Xiaoyun Chen, Naga Chalasani, Xiao‐Ming Yin
Publikováno v:
Hepatology Communications, Vol 6, Iss 12, Pp 3349-3362 (2022)
Abstract A growing body of evidence has indicated an expanding functional network of B‐cell lymphoma 2 (BCL‐2) family proteins beyond regulation of cell death and survival. Here, we examined the role and mechanisms of BH3 interacting‐domain dea
Externí odkaz:
https://doaj.org/article/0e5360b219444b849366cce026cd33b9
Autor:
Yan Wang, Matthew Hamang, Alexander Culver, Huaizhou Jiang, Jennifer Yanum, Veronica Garcia, Joonyong Lee, Emily White, Praveen Kusumanchi, Naga Chalasani, Suthat Liangpunsakul, Benjamin C. Yaden, Guoli Dai
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2812-2826 (2022)
Abstract The role of activin B, a transforming growth factor β (TGFβ) superfamily cytokine, in liver health and disease is largely unknown. We aimed to investigate whether activin B modulates liver fibrogenesis. Liver and serum activin B, along wit
Externí odkaz:
https://doaj.org/article/1c9c2fe02fc048d98c59f9dc5a348679
Autor:
Mark D. Muthiah, Ekaterina Smirnova, Puneet Puri, Naga Chalasani, Vijay H. Shah, Calvin Kiani, Stephanie Taylor, Faridoddin Mirshahi, Arun J. Sanyal
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1073-1089 (2022)
The perturbations in bile acids (BAs) in alcohol‐associated hepatitis (AH) and its relationship to disease severity is not well defined. The aims of this study were to define (1) the effects of heavy alcohol consumption on BAs and related microbiom
Externí odkaz:
https://doaj.org/article/5ba72c522fbc46c18e6bf22c0522b8cf
Autor:
Kavish R. Patidar, Jennifer L. Peng, Harleen Kaur, Astin Worden, Carla D. Kettler, Francis Pike, Caitriona A. Buckley, Eric S. Orman, Archita P Desai, Lauren D. Nephew, Chandrashekhar A. Kubal, Samer Gawrieh, Naga Chalasani, Marwan S. Ghabril
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1090-1099 (2022)
Differences in mortality between critically ill patients with severe alcohol‐associated hepatitis (sAH) and acute‐on‐chronic liver failure (ACLF) and non‐sAH ACLF (i.e., ACLF not precipitated by sAH) are unknown. Such differences are importan
Externí odkaz:
https://doaj.org/article/29e4697b69064a9a970ee66ddcf06464
Autor:
Lauren D. Nephew, Dipika Gupta, Allie Carter, Archita P. Desai, Marwan Ghabril, Kavish R. Patidar, Eric Orman, Alisha Dziarski, Naga Chalasani
Publikováno v:
Hepatology Communications, Vol 7, Iss 3, Pp e0058-e0058 (2023)
Background and Aims:. The social determinants of health can pose barriers to accessing cancer screening and treatment and have been associated with cancer mortality. However, it is not clear whether area deprivation is independently associated with m
Externí odkaz:
https://doaj.org/article/9d8294e0ccc44a34a00f0b71321ca78c
Autor:
Tiebing Liang, Janaiah Kota, Kent E. Williams, Romil Saxena, Samer Gawrieh, Xiaoling Zhong, Teresa A. Zimmers, Naga Chalasani
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14564 (2023)
MicroRNA-29a (miR-29a) is a well characterized fibro-inflammatory molecule and its aberrant expression is linked to a variety of pathological liver conditions. The long-term effects of a high-fat diet (HFD) in combination with different levels of EtO
Externí odkaz:
https://doaj.org/article/5beccac89bf04bf9a09f941c5b4ea189
Autor:
Samer Gawrieh, Kathleen E Corey, Jordan E Lake, Niharika Samala, Archita P Desai, Paula Debroy, Julia A Sjoquist, Montreca Robison, Mark Tann, Fatih Akisik, Surya S Bhamidipalli, Chandan K Saha, Kimon Zachary, Gregory K Robbins, Samir K Gupta, Raymond T Chung, Naga Chalasani
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0279685 (2023)
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in persons with HIV (PWH) (HIV-NAFLD). It is unknown if HIV-NAFLD is associated with impairment in health-related quality of life (HRQOL). We examined HRQOL in PWH with and wi
Externí odkaz:
https://doaj.org/article/50cb0378014b48f99390ce45308ec5c7