Zobrazeno 1 - 10
of 646
pro vyhledávání: '"Naftali Kaminski"'
Autor:
Yunqing Liu, Ningshan Li, Ji Qi, Gang Xu, Jiayi Zhao, Nating Wang, Xiayuan Huang, Wenhao Jiang, Huanhuan Wei, Aurélien Justet, Taylor S. Adams, Robert Homer, Amei Amei, Ivan O. Rosas, Naftali Kaminski, Zuoheng Wang, Xiting Yan
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract Spatial barcoding-based transcriptomic (ST) data require deconvolution for cellular-level downstream analysis. Here we present SDePER, a hybrid machine learning and regression method to deconvolve ST data using reference single-cell RNA sequ
Externí odkaz:
https://doaj.org/article/9cde57efd6d548c2993a333c6044cee4
Autor:
Joseph A. Bell, Elizabeth R. Davies, Christopher J. Brereton, Milica Vukmirovic, James J.W. Roberts, Kerry Lunn, Leanne Wickens, Franco Conforti, Robert A. Ridley, Jessica Ceccato, Lucy N. Sayer, David A. Johnston, Andres F. Vallejo, Aiman Alzetani, Sanjay Jogai, Ben G. Marshall, Aurelie Fabre, Luca Richeldi, Phillip D. Monk, Paul Skipp, Naftali Kaminski, Emily Offer, Yihua Wang, Donna E. Davies, Mark G. Jones
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101695- (2024)
Summary: Matrix stiffening by lysyl oxidase-like 2 (LOXL2)-mediated collagen cross-linking is proposed as a core feedforward mechanism that promotes fibrogenesis. Failure in clinical trials of simtuzumab (the humanized version of AB0023, a monoclonal
Externí odkaz:
https://doaj.org/article/28bf070de21f4af1b6319da757012509
Autor:
Sally Singh, Mark Jones, Michael Kreuter, Maria Molina-Molina, Imre Noth, Andrew Wilson, Martin Brutsche, Naftali Kaminski, Gary M Hunninghake, Michael Keane, Nazia Chaudhuri, Ian Forrest, Bruno Crestani, Fernando J Martinez, Mohsen Sadatsafavi, Luca Richeldi, Antje Prasse, Fasihul Khan, Iain Stewart, Steve Jones, Gisli Jenkins, Gauri Saini, David Turner, Killian Hurley, Lucilla Piccari, Andrew Palmer, Joseph A Lasky, Simon Hart, Joyce Lee, Anthony Gordon, John Blaikley, Kirsty Hett, Helmut Prosch, Elisabeth Bendstrup, Christopher Huntley, Helen Parfrey, Huzaifa Adamali, Paul Beirne, Stephen Bianchi, George Chalmers, Sophie Fletcher, Peter George, Michael Gibbons, Mark Spears, Laura Fabbri, Felix Chua, Michael Henry, Cormac McCarthy, Sabrina Paganoni, Joseph Jacob, Mark Toshner, Bibek Gooptu, Andrew Briggs, Philip L Molyneaux, Athol Wells, Charlotte Summers, Leticia Kawano-Dourado, Ian Glaspole, Melanie Quintana, Christopher J Ryerson, Paolo Spagnolo, Francesco Bonella, Carisi Anne Polanczyk, Anjali Crawshaw, Laurence Pearmain, Avinash Anil Nair, Raphaël Borie, Alexandre Biasi Cavalcanti, Emanuela Falaschetti, Jonathan Chung, James Eaden, Kate Johnson, Shaney Barratt, Chris Ryerson, Juergen Behr, Andreas Guenther, Nik Hirani, Karin Storrer, Deepak Talwar, Claudia Ravaglia, Katerina Antoniou, Sara Freitas, Carlo Vancheri, Laura Price, Amanda Goodwin, Daniel Chambers, Gunnar Gudmundsson, Roger Lewis, Ingrid Cox, Anne Holland, Erica Farrand, Argyrios Tzouvelekis, Rui Rolo, Duncan Richards, Larissa Schwarzkopf, Sabina Guler, Devesh Dhasmana, Claudia Valenzuela, John S Kim, Louise Crowley, Lisa Watson, Amanda Bravery, Elisabetta Balestro, Wendy Adams, Francesco Lombardi, Ali Mojibian, Ana Etges, Ana Sousa Marcelino Boshoff, Anne Bergeron Anna-MariaHoffmann-Vold, Athina Trachalaki, Barbara Wendelberger, Bhavika Kaul Ben Hope-Gill, Bruno Baldi, Carlos Robalo, Chris Grainge, Christophe von Garnier, Conal Hayton, Dapeng Wang, Daphne Bablis, David Thicket, Deji Adegunsoye, Devaraj Anand, Dhruv Parek, Diane Griffiths, Eliana Santucci, Eliza Tsitoura, Emma Karlsen, Ena Gupta, Harold Collard, Hernan Fainberg, Iazsmin Bauer-Ventura, Irina Strambu, Jacobo Sellares, Janet Johnston, Jeff Swigris, Karina Negrelli, Katarzyna Lewandowska, Katrin Hostettler, Kerri Johannson, Liam Galvin, Lisa G. Spencer, Manuela Funke Chambour, Marlies Wijsenbeek-Lourens, Martina Vasakova, Milena Man Iuliu Hatieganu, Nick Weatherley, Ovidiu Fira Mladinescu Victor Babes, Peter Bryce, Pilar Rivera Ortega, Radu Crisan-Dabija, Rahul Maida, Sara Piciucchi, Shama Malik, Simone Dal Corso, Stefan Stanel
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Objectives Mycophenolate mofetil (MMF) and azathioprine (AZA) are immunomodulatory treatments in interstitial lung disease (ILD). This systematic review aimed to evaluate the efficacy of MMF or AZA on pulmonary function in ILD.Design Population inclu
Externí odkaz:
https://doaj.org/article/2ac47dada7d648a4a2a2a9b8b2f6ab10
Autor:
Tobias Heigl, Janne Kaes, Celine Aelbrecht, Jef Serré, Yoshito Yamada, Vincent Geudens, Anke Van Herck, Arno Vanstapel, Annelore Sacreas, Sofie Ordies, Anna Frick, Berta Saez Gimenez, Jan Van Slambrouck, Hanne Beeckmans, Nilüfer A. Acet Oztürk, Michaela Orlitova, Annemie Vaneylen, Sandra Claes, Dominique Schols, Greetje Vande Velde, Jonas Schupp, Naftali Kaminski, Markus Boesch, Hannelie Korf, Schalk van der Merwe, Lieven Dupont, Jeroen Vanoirbeek, Laurent Godinas, Dirk E. Van Raemdonck, Wim Janssens, Ghislaine Gayan-Ramirez, Laurens J. Ceulemans, John E. McDonough, Erik K. Verbeken, Robin Vos, Bart M. Vanaudenaerde
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionChronic rejection is a major complication post-transplantation. Within lung transplantation, chronic rejection was considered as airway centred. Chronic Lung Allograft Dysfunction (CLAD), defined to cover all late chronic complications, m
Externí odkaz:
https://doaj.org/article/523cb3938ed14de6b83dbb256d799395
Autor:
Rachana R. Chandran, Taylor S. Adams, Inamul Kabir, Eunate Gallardo-Vara, Naftali Kaminski, Brigitte N. Gomperts, Daniel M. Greif
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Alveolarization ensures sufficient lung surface area for gas exchange, and during bulk alveolarization in mice (postnatal day [P] 4.5–14.5), alpha-smooth muscle actin (SMA)+ myofibroblasts accumulate, secrete elastin, and lay down alveolar septum.
Externí odkaz:
https://doaj.org/article/b942c13124314f1096ff19c7c8478d5e
Autor:
Ilianna Barbayianni, Paraskevi Kanellopoulou, Dionysios Fanidis, Dimitris Nastos, Eleftheria-Dimitra Ntouskou, Apostolos Galaris, Vaggelis Harokopos, Pantelis Hatzis, Eliza Tsitoura, Robert Homer, Naftali Kaminski, Katerina M. Antoniou, Bruno Crestani, Argyrios Tzouvelekis, Vassilis Aidinis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The activation and accumulation of lung fibroblasts resulting in aberrant deposition of extracellular matrix components, is a pathogenic hallmark of Idiopathic Pulmonary Fibrosis, a lethal and incurable disease. In this report, increased exp
Externí odkaz:
https://doaj.org/article/8ef8129fe42e4791815698944372c750
Autor:
Georgia Charkoftaki, Reza Aalizadeh, Alvaro Santos-Neto, Wan Ying Tan, Emily A. Davidson, Varvara Nikolopoulou, Yewei Wang, Brian Thompson, Tristan Furnary, Ying Chen, Elsio A. Wunder, Andreas Coppi, Wade Schulz, Akiko Iwasaki, Richard W. Pierce, Charles S. Dela Cruz, Gary V. Desir, Naftali Kaminski, Shelli Farhadian, Kirill Veselkov, Rupak Datta, Melissa Campbell, Nikolaos S. Thomaidis, Albert I. Ko, Yale IMPACT Study Team, David C. Thompson, Vasilis Vasiliou
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-17 (2023)
Abstract Over the last century, outbreaks and pandemics have occurred with disturbing regularity, necessitating advance preparation and large-scale, coordinated response. Here, we developed a machine learning predictive model of disease severity and
Externí odkaz:
https://doaj.org/article/2f4a257343224b1581834ef8402d7d6e
iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects
Autor:
Yunqing Liu, Jiayi Zhao, Taylor S. Adams, Ningya Wang, Jonas C. Schupp, Weimiao Wu, John E. McDonough, Geoffrey L. Chupp, Naftali Kaminski, Zuoheng Wang, Xiting Yan
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background Single-cell RNA sequencing (scRNA-seq) technology has enabled assessment of transcriptome-wide changes at single-cell resolution. Due to the heterogeneity in environmental exposure and genetic background across subjects, subject e
Externí odkaz:
https://doaj.org/article/98bb000233a34cca8225fba23b3cf131
Autor:
Ana B. Pavel, Carly Garrison, Lingqi Luo, Gang Liu, Daniel Taub, Ji Xiao, Brenda Juan-Guardela, John Tedrow, Yuriy O. Alekseyev, Ivana V. Yang, Mark W. Geraci, Frank Sciurba, David A. Schwartz, Naftali Kaminski, Jennifer Beane, Avrum Spira, Marc E. Lenburg, Joshua D. Campbell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) are clinically and molecularly heterogeneous diseases. We utilized clustering and integrative network analyses to elucidate roles for microRNAs (miRNAs) and miR
Externí odkaz:
https://doaj.org/article/3ab462eb96c1423b8efb64bcedd52c26
Autor:
Michela Biancolella, Vito Luigi Colona, Lucio Luzzatto, Jessica Lee Watt, Giorgio Mattiuz, Silvestro G. Conticello, Naftali Kaminski, Ruty Mehrian-Shai, Albert I. Ko, Gregg S. Gonsalves, Vasilis Vasiliou, Giuseppe Novelli, Juergen K. V. Reichardt
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-14 (2023)
Abstract Three and a half years after the pandemic outbreak, now that WHO has formally declared that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on recent developments in genetic and genomic research on COVID-1
Externí odkaz:
https://doaj.org/article/4736bcccfd6844fc8b094ab42958a024