Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nafiisha Genet"'
Autor:
Nicholas W. Chavkin, Gael Genet, Mathilde Poulet, Erin D. Jeffery, Corina Marziano, Nafiisha Genet, Hema Vasavada, Elizabeth A. Nelson, Bipul R. Acharya, Anupreet Kour, Jordon Aragon, Stephanie P. McDonnell, Mahalia Huba, Gloria M. Sheynkman, Kenneth Walsh, Karen K. Hirschi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
During blood vessel development, endothelial cells become specified toward arterial or venous fates. Chavkin et al find that distinct endothelial cell cycle states provide windows of opportunity for the molecular induction of arterial or venous fate.
Externí odkaz:
https://doaj.org/article/dd49956f70db4db48d1cedcdc042f6bb
Autor:
Nafiisha Genet, Gael Genet, Nicholas W. Chavkin, Umadevi Paila, Jennifer S. Fang, Hema H. Vasavada, Joshua S. Goldberg, Bipul R. Acharya, Neha S. Bhatt, Kasey Baker, Stephanie P. McDonnell, Mahalia Huba, Danya Sankaranarayanan, Gerry Z.M. Ma, Anne Eichmann, Jean-Leon Thomas, Charles ffrench-Constant, Karen K. Hirschi
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112371- (2023)
Summary: The subventricular zone (SVZ) is the largest neural stem cell (NSC) niche in the adult brain; herein, the blood-brain barrier is leaky, allowing direct interactions between NSCs and endothelial cells (ECs). Mechanisms by which direct NSC-EC
Externí odkaz:
https://doaj.org/article/b6ab1a4c86c8452cbbc5037eef29bb4a
Autor:
Gael Genet, Kevin Boyé, Thomas Mathivet, Roxana Ola, Feng Zhang, Alexandre Dubrac, Jinyu Li, Nafiisha Genet, Luiz Henrique Geraldo, Lorena Benedetti, Steffen Künzel, Laurence Pibouin-Fragner, Jean-Leon Thomas, Anne Eichmann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
VEGF-A/VEGFR2 signaling is a key driver of endothelial cell migration during sprouting angiogenesis. Here Genet et al. show that endophilin A2 regulates these processes by mediating clathrin-independent VEGFR2 internalization.
Externí odkaz:
https://doaj.org/article/a65242a5aee94d9999a57269b93f9bd4
Autor:
Nafiisha Genet, Karen K. Hirschi
Publikováno v:
Regenerative Medicine
The use of neural stem cell (NSC) therapy for the treatment of stroke patients is successfully paving its way into advanced phases of large-scale clinical trials. To understand how to optimize NSC therapeutic approaches, it is fundamental to decipher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022f096cd7db7a575aab9f4ecc1721cf
https://doi.org/10.2217/rme-2021-0022
https://doi.org/10.2217/rme-2021-0022
Autor:
Nafiisha Genet, Gael Genet, Jennifer S. Fang, Nicholas W. Chavkin, Hema H. Vasavada, Joshua S. Goldberg, Bipul R. Acharya, Neha Bhatt, Kasey Baker, Stephanie McDonnell, Mahalia R. Huba, Gerry Ma, Anne Eichmann, Jean Leon Thomas, Charles ffrench-Constant, Karen K. Hirschi
The subventricular zone (SVZ) is the largest neural stem cell (NSC) niche in the adult brain; herein, the blood-brain barrier is leaky, allowing direct interactions between NSCs and endothelial cells (ECs). Mechanisms by which direct NSC-EC interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da731c219f3fa2e0a8e6fd06e0d2c8d2
https://doi.org/10.1101/2022.02.28.482353
https://doi.org/10.1101/2022.02.28.482353
Autor:
Karen K. Hirschi, Seyoung Lee, Anjelica L. Gonzalez, Rita Matta, Nafiisha Genet, Jean-Leon Thomas
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports, 2019, 9 (1), pp.17798. ⟨10.1038/s41598-019-54167-1⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.17798. ⟨10.1038/s41598-019-54167-1⟩
Scientific Reports
Scientific Reports, 2019, 9 (1), pp.17798. ⟨10.1038/s41598-019-54167-1⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.17798. ⟨10.1038/s41598-019-54167-1⟩
Stem cell therapies demonstrate promising results as treatment for neurological disease and injury, owing to their innate ability to enhance endogenous neural tissue repair and promote functional recovery. However, delivery of undifferentiated and vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5022c81858050055317ba923231a3e0
http://link.springer.com/article/10.1038/s41598-019-54167-1
http://link.springer.com/article/10.1038/s41598-019-54167-1
Autor:
Karen K. Hirschi, Nafiisha Genet, Kenneth Walsh, Nicholas W. Chavkin, Elizabeth A. Nelson, Stephanie P. McDonnell, Hema Vasavada, Gael Genet, Mathilde Poulet, Mahalia Huba, Corina Marziano, Anupreet Kour
SummaryFormation and maturation of a functional blood vascular system is required for the development and maintenance of all tissues in the body. During the process of blood vessel development, primordial endothelial cells are formed and become speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6e3d98e6f8fedee936b18ae0568cbce
https://doi.org/10.1101/2020.08.12.246512
https://doi.org/10.1101/2020.08.12.246512
Autor:
Paul Robillard, Raphaël Thuillet, Christophe Guignabert, Elise Maurat, Véronique Freund-Michel, Raffaella Soleti, Frederic Delcambre, Baptiste Rode, Ly Tu, Eric Dumas De La Roque, Patrick Berger, Carole Phan, Nafiisha Genet, Claire Bouvard, Roger Marthan, Marilyne Campagnac, Thibaud Parpaite, Christelle Guibert, Laurent Cronier, Jean-Pierre Savineau
Publikováno v:
European Respiratory Journal
European Respiratory Journal, European Respiratory Society, In press, pp.1900169. ⟨10.1183/13993003.00169-2019⟩
European Respiratory Journal, European Respiratory Society, 2020, 55 (3), pp.1900169. ⟨10.1183/13993003.00169-2019⟩
European Respiratory Journal, European Respiratory Society, In press, pp.1900169. ⟨10.1183/13993003.00169-2019⟩
European Respiratory Journal, European Respiratory Society, 2020, 55 (3), pp.1900169. ⟨10.1183/13993003.00169-2019⟩
The mechanisms underlying pulmonary hypertension (PH) are complex and multifactorial, and involve different cell types that are interconnected through gap junctional channels. Although connexin (Cx)-43 is the most abundant gap junction protein in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9348d9c5a1e2048f32415f1285b0a237
https://hal.univ-angers.fr/hal-02430904
https://hal.univ-angers.fr/hal-02430904
Publikováno v:
Current Stem Cell Reports
Purpose of Review Considerable progress has been made in the field of stem cell research; nonetheless, the use of stem cells for regenerative medicine therapies, for either endogenous tissue repair or cellular grafts post injury, remains a challenge.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4557042a1000ae4ff77770b62a7fcfce
https://pubmed.ncbi.nlm.nih.gov/29600160
https://pubmed.ncbi.nlm.nih.gov/29600160
Autor:
Mathilde Dubois, Marie Billaud, Roger Marthan, Jennifer Gillibert-Duplantier, Nafiisha Genet, Rodrigue Rossignol, Jean-Pierre Savineau, Christelle Guibert, Brant E. Isakson
Publikováno v:
Frontiers in Physiology
Serotonin (5-HT) is a potent vasoconstrictor agonist and contributes to several vascular diseases including systemic or pulmonary hypertension and atherosclerosis. Although superoxide anion (O2•) is commonly associated to cellular damages due to O2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c522b646d6eba7e8b48f98f8d9bc737c
https://doi.org/10.3389/fphys.2017.00076
https://doi.org/10.3389/fphys.2017.00076